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Exam 1
Exam 1
67
Pharmacology
Graduate
01/29/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

zolpidem

 

Definition
BDZ related drug
Term
Zaleplon
Definition
BDZ-related drug
Term
eszopiclone
Definition
BDZ related drug
Term
Gonadorelin
Definition
GnRH human synthetic
Term
Buserelin
Definition
GnRH agonist
Term
Leuprolide
Definition
GnRH agonist
Term
Histrelin
Definition
GnRH agonist
Term
Nafarelin
Definition
GnRH agonist
Term
Triptorelin
Definition
GnRH agonit
Term
Ganirelix
Definition
GnRH antagonist
Term
Cetrolix
Definition
GnRH antagonist
Term
Abarelix
Definition
GnRH antagonist
Term
Degarelix
Definition
GnRH antagonist
Term
Menotropin
Definition
puried from postmenopausal women, mixture of FSH and LH
Term
urofollitropin
Definition
purified human follicle stimulating hormone
Term
folitropin alfa/beta
Definition
recombinant FSH
Term
Leutropin alfa
Definition
recombinant LH
Term
estrogen
Definition
SHBG, alpha and beta receptors. Bind to EREs
Term
Projesterone
Definition
natural progesterone
Term
hydroxyprogesterone
Definition
progesterone; bind to nuclear receptors (transcription factors) and regular gene expression; carbohydrate metabolism
Term
medroxyprogesterone
Definition
progesterone; bind to nuclear receptors (transcription factors) and regular gene expression; carbohydrate metabolism
Term
dimethisterone
Definition
progesterone; bind to nuclear receptors (transcription factors) and regular gene expression; carbohydrate metabolism
Term
dimethisterone
Definition
progesterone; bind to nuclear receptors (transcription factors) and regular gene expression; carbohydrate metabolism
Term
norethindrone
Definition
progesterone; bind to nuclear receptors (transcription factors) and regular gene expression; carbohydrate metabolism
Term
desogestrel
Definition
progesterone; bind to nuclear receptors (transcription factors) and regular gene expression; carbohydrate metabolism
Term
dorgestrel
Definition
progesterone; bind to nuclear receptors (transcription factors) and regular gene expression; carbohydrate metabolism
Term
ethynodiol
Definition
progesterone; bind to nuclear receptors (transcription factors) and regular gene expression; carbohydrate metabolism
Term
Tamoxifen
Definition
SERM; for breast cancer
Term
Raloxifene
Definition
SERM; for osteoporosis
Term
Toremifene
Definition
SERM
Term
Toremifene
Definition
SERM; similar to Tamoxifen
Term
Clomiphene
Definition
SERM; inhibits estrogen neg. feedback inhibition of FSH and LH release; may exhibit anti estrogen effects on uterus and cervix
Term
Fluvestrant
Definition
estrogen antagonist; treatment of breast cancer
Term
Anastrazole
Definition
aromatase inhibitors (AI); used in adjunct treatment in ER positive breast cancer
Term
Letrozole
Definition
aromatase inhibitors (AI); used in adjunct treatment in ER positive breast cancer
Term
exmestane
Definition
aromatase inhibitors (AI); used in adjunct treatment in ER positive breast cancer
Term
Mifepristone
Definition
anti-progesterone; inhibits progesterone; early termination of pregnancy
Term
Danazol
Definition
inhbits FSH and LH; used for endometriosis, and fibrocyctic breast disease
Term
testosterone
Definition
androgen; anabolic agent that is converted via 5- alpha rectase
Term
methyltestosterone
Definition
androgen replacement therapy
Term
fluoxymesterone
Definition
anabolic steroid for anemia, bone pain in osteoporsis, and increasing weight (androgen receptor agonits)
Term
Oxandrolone
Definition
anabolic steroid for anemia, bone pain in osteoporsis, and increasing weight (androgen receptor agonits)
Term
oxymetholone
Definition
anabolic steroid for anemia, bone pain in osteoporsis, and increasing weight (androgen receptor agonits)
Term
nandrolone
Definition
anabolic steroid for anemia, bone pain in osteoporsis, and increasing weight (androgen receptor agonits)
Term
ketoconazole
Definition
antifungal; inhibit steroid synthesis (anti-androgen)
Term
Finasteride
Definition
5-alpha reductase inhibitor; male pattern baldness; type II
Term
Dutasteride
Definition
5-alpha reductase inhibitor; equal for type I and II
Term
flutamide
Definition
androgen receptor blocker; blockers androgen receptors in prostate to reduce growth and treat metastatic prostate cancer
Term
Bicalutamide
Definition
androgen receptor blocker; blockers androgen receptors in prostate to reduce growth and treat metastatic prostate cancer
Term
Nilutamide
Definition
androgen receptor blocker; blockers androgen receptors in prostate to reduce growth and treat metastatic prostate cancer
Term
Cyporterone
Definition
steroid androgen receptor antagonist
Term
cyclophosphamide
Definition
alkylating agent; widest spectrum of nitrogen mustards; activated by CYP450 to active metbolite--bladder toxcity
Term
ifosfamide
Definition
alkylating agent
Term
Mesna
Definition
inactivates acrolein
Term
Doxorubicin
Definition
antracycline antiobiotics; inhibits topoisomerase leading to DNA beaks and release of free radicals
Term
Daunurubicin
Definition
antracycline antiobiotics; inhibits topoisomerase leading to DNA beaks and release of free radicals
Term
epirubicin
Definition
antracycline antiobiotics; inhibits topoisomerase leading to DNA beaks and release of free radicals
Term
idarubicin
Definition
antracycline antiobiotics; inhibits topoisomerase leading to DNA beaks and release of free radicals
Term
DMSO
Definition
antedote for anthracycline toxicity
Term
dexrazoxane
Definition
antidote for anthracycline induced cardiomyopathy; iron chelator
Term
cisplatin
Definition
platinum compounds
Term
carboplatin
Definition
platinum compounds
Term
oxaliplatin
Definition
platinum compounds
Term
Vincristine
Definition
Vinca alkaloids
Term
vinblastine
Definition
Vinca alkaloids
Term
vinorelbine
Definition
Vinca alkaloids
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