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Exam 1 Drugs
Important Themes
11
Pharmacology
Graduate
10/08/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

 

 

 

 

Work only on Gm - bacteria

Definition

 

 

 

Monobactum

Polymixin

Nalidixic Acid

Lincosamides (lincomycin and clindamycin)

Term

 

 

 

 

Work only on Gm + bacteria

Definition

 

 

 

Vancomycin 

Rifamycin 

Ciprofloxacin

Linezolid (gram + cocci and drug resistant enterococci)

Term

 

 

 

 

Isoniazid

Definition

 

 

Narrow Spectrum-

work only on mycobacteria by inhibiting synthesis of mycolic acid 

 

Term

 

 

 

Work only on anaerobic bacteria

Definition

 

 

 

Metronidazole 

Lincosamides (Lincomycin and clindamycin- gram negative anaerobes)

Term

 

 

 

 

Work only aerobic bacteria 

Definition

 

 

 

Aminoglycosides

Term

 

 

 

 

Synergistic Pairs 

Definition

 

 

 

aminoglycosides and B- lactams

streptogramins- streptogramin A and B

Sulfonamides and Trimethoprims- work in different steps of folate synthesis

Term

 

 

 

Bind to 23 S RNA

Definition

 

 

 

Macrolides and Lincosamides (clindamycine and lincomycin)

-> both will have resistance

Term

 

 

 

Broad Spectrum

Definition

 

 

 

Carbapenem

Tetracyclin

Macrolides (Clarithromycin, Erythromycin, Azithromycin)

Term

 

 

 

Narrow Spectrum

Definition

 

 

 

Monobactum (Gm -)

Isoniazid (mycobacteria)

Linezolid (gram + cocci) 

Lincosamides (anaerobic gram - rods) 

Term

 

 

 

 

Bacteriacidal 

Definition

 

 

 

B- lactams (bacteria surface pathogenicity)

 

Drugs that affect nucleic acid synthesis (Quniolones [Nixidic Acid, Cipro], Metronidazole, Rifampin)

 

Aminoglycosides (bind irreversibly to 30 S subunit) 

Term

 

 

 

 

BacteriSTATIC 

Definition

 

 

 

Chloramphenicol (reversibly binds to 50 S subunit)

Sulfonamides and Trimethoprim (inhibit folate synthesis)

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