| Term 
 
        |         Work only on Gm - bacteria |  | Definition 
 
        |       Monobactum Polymixin Nalidixic Acid Lincosamides (lincomycin and clindamycin) |  | 
        |  | 
        
        | Term 
 
        |         Work only on Gm + bacteria |  | Definition 
 
        |       Vancomycin  Rifamycin  Ciprofloxacin Linezolid (gram + cocci and drug resistant enterococci) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |     Narrow Spectrum- work only on mycobacteria by inhibiting synthesis of mycolic acid    |  | 
        |  | 
        
        | Term 
 
        |       Work only on anaerobic bacteria |  | Definition 
 
        |       Metronidazole  Lincosamides (Lincomycin and clindamycin- gram negative anaerobes) |  | 
        |  | 
        
        | Term 
 
        |         Work only aerobic bacteria  |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        |       aminoglycosides and B- lactams streptogramins- streptogramin A and B Sulfonamides and Trimethoprims- work in different steps of folate synthesis |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |       Macrolides and Lincosamides (clindamycine and lincomycin) -> both will have resistance |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |       Carbapenem Tetracyclin Macrolides (Clarithromycin, Erythromycin, Azithromycin) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |       Monobactum (Gm -) Isoniazid (mycobacteria) Linezolid (gram + cocci)  Lincosamides (anaerobic gram - rods)  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |       B- lactams (bacteria surface pathogenicity)   Drugs that affect nucleic acid synthesis (Quniolones [Nixidic Acid, Cipro], Metronidazole, Rifampin)   Aminoglycosides (bind irreversibly to 30 S subunit)  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |       Chloramphenicol (reversibly binds to 50 S subunit) Sulfonamides and Trimethoprim (inhibit folate synthesis) |  | 
        |  |