Term
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Definition
GM-
peritrichous flagella
lactose fermentation
faculatatively anaerobic
normal flora and pathogenic mutants |
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Term
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Definition
entertoxigenic (etec)
enterhemorrhagic (ehec)
enterinvasive (eiec) |
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Term
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Definition
| watery diarrhea produced by choler-like entertoxin |
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Term
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Definition
bloody diarrhea produced by verotoxin (cytotoxin)
HUS complications |
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Term
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Definition
bloody diarrhea
enters cells and causes tissue disruption and inflammation |
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Term
| E. coli O157:H7 differences |
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Definition
antigenic - O157 on LPS and H7 on flagella
growth - does not ferment sorbitol |
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Term
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Definition
| agar, peptone, lactose, bile salts, neutral red |
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Term
| red dots on MacConkey agar mean... |
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Definition
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Term
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Definition
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Term
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Definition
| common vehicle - fecal contaminated undercooked beef (hamburger) |
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Term
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Definition
| modified MacConkey agar (SMAC) |
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Term
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Definition
sorbitol rather than lactose
cefixime and K tellurite - suppress other sorbitol fermenters |
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Term
| white dots on SMAC agar mean... |
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Definition
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Term
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Definition
3-5 day incubation period
stomach cramps, bloody diarrhea, vomiting, maybe fever |
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Term
| Hemolytic uremic syndrome |
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Definition
(HUS) develops in 5-10% of patients
develops as disease subsides
less urination, tired, loosing pick color |
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Term
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Definition
| oral fecal route from contaminated beef |
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Term
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Definition
| adhesins on fimbriae attach to large intestine epithelium |
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Term
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Definition
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Term
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Definition
shiga-like cytotoxin kills cells
vascular damage allow inflammation mediators into bloodstream which can lead to HUS
endotoxin - interlukin and TNF |
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Term
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Definition
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Term
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Definition
fluids
no antibiotics or antidiarrheals
hospitalization with HUS |
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Term
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Definition
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