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Equine Disease & Injury
Signs of Health and Disease
26
Other
Undergraduate 3
09/21/2010

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Term
NATURAL INNATE IMMUNITY
Definition
present at birth
relatively non-specific
natural barriers of animal (ex. skin)
mucous membrane
cellular actions
antibody production
Term
ACQUIRED IMMUNITY
Definition
specific immunity against a foreign agent
Term
ACTIVELY ACQUIRED
Definition
the animal has gotten a specific immunity against an agent for a specific infection
Natural-naturally actually infected
Artificial-vaccines/shots
Term
B LYMPHOCYTES
Definition
actually produce antibodies
Term
T LYMPHOCYTES
Definition
do not produce antibodies, but are turn on for B-cells
Term
PHAGOCYTIC CELLS
Definition
monocytes - kick started by T-cells
Term
PASSIVELY ACQUIRED
Definition
not making it ourselves
given to animal somehow
ex. mare's milk
Term
MATERNAL ANTIBODIES
Definition
colostrum
Term
ARTIFICIAL
Definition
injections of hyper-immune serum
Term
DEFENSIVE MECHANISMS: PRIMARY
Definition
skin & mucous membranes
body secretions on the skin (ex. sweat)
pH of secretions help prevent MOs
respiratory secretions & functions
lymphatic system
tissue fluids
inflammation
fever
Term
DEFENSE MECHANISMS: SECONDARY
Definition
phagocytosis: ingesting and destroying foreign particles
WBC: granulocytes, monocytes
Term
STEPS OF PHAGOCYTOSIS
Definition
inflammation: mobilization of WBC due to chemical release
ingestion of bacteria
destroying of bacteria
Term
MACROPHAGES
Definition
neutrophils: 1st response attract other cells
eosinophils: very attracted to histamine, allergic reaction
monocytes: really big killer cells
Term
DEFENSE MECHANISMS: TERTIARY
Definition
B lymphocytes: produce antibodies
T lymphocytes: turn on reaction, activate B cells and other phagocytic cells
Term
PLASMA: FIBINOGEN
Definition
clotting, inflammatory proteins
Term
PLASMA: SERUM
Definition
plasma-clotting factors, organ secretion, minerals, enzymes
Term
WHITE BLOOD CELLS
Definition
leukocytes: comes from bone marrow
Term
NEUTROPHILS
Definition
killer cells
bacterial infections
"segs" mature
"bands" immature
Term
BASOPHILS
Definition
allergies
hypersensitivity
inflammatory
Term
EOSINOPHILS
Definition
histamine
allergic reaction, injury sites, GI tract, skin and lungs
Term
LYMPHOCYTES
Definition
(S)CID foals do not have these "smart bombs"
B-cells/t-cells can live for weeks/years
Term
MONOCYTES
Definition
largest cells
last to show up
a lot present during long term illness
"killer cells"
Term
COMPLETE BLOOD COUNT (CBC)
Definition
red blood cells(RBC)- 7-12 million/cc
packed cell volume(PCV)- cells (34-50%) vs plasma(remaining)
Hemoglobing- 11-19g/100 ml of blood
white blood cells (WBC)- 8,000-11,000 cells/cc
Term
ANTIBODIES
Definition
produced by B-cells-immunoglobulins
IgG-70% of all antibodies
IgM-10% of all antibodies, 1st Ig produced in an immune response then IgGs take over
IgA-15-20% of serum antibodies
IgD-less than 1% of antibodies, in membranes of lymphocytes to help differentiation
IgE- less than 1% of antibodies, functions in immune response to parasites, on surface of basophils
IgE- functions in immune response to parasites
Term
LIVE VACCINES
Definition
adjuvant: help preserve the vaccine along w/ refrigeration, carrying solution, modified organism is weaker, trigger response in animal to make antibodies
Term
KILLED VACCINES
Definition
organism is dead but response to it will still create antibodies against organisms
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