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Equations
Pharm Equations
8
Pharmacology
Professional
01/19/2012

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Term
Half Life = 0.7 x Vd/Clearance
Definition
Half life equation
Term
Loading Dose = Vd x Target Concentration
Definition
Loading Dose equation
Term
Dose of new form = dose x F current form/F of new dosage form
Definition
Calculate New Dose
Term
Vd = dose/plasma concentration
Definition
Volume of distribution
(note that the larger the Vd the longer it takes to be excreted, thus a larger half life)
Term
Amount of Drug Reaching Systemic Circulation = F x Dose Given
Definition
Amount of Drug Reaching Systemic Circulation
Term
Clearance = Rate of elimination/Concentration
Definition
Clearance
Term
Dosing Rate = Clearance X Target Concentration
Definition
Dosing Rate
Term
Maintenance Dosing = (Dosing Rate x Dosing Interval)/F
Definition
Maintenance Dosing
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