Term
| What are the 5 tissue types? |
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Definition
| Epithelium, Muscle, Connective Tissue, Nerve, Lymphatics |
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Term
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Definition
| Protection (Skin), Secretion (Exocrine, Endocrine), Sensation (Olfactory), Contractility (Myoepithelial), Absorption (Intestines) |
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Term
| Characteristics of Epithelium |
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Definition
| Cells are in close together, Derived from endoderm, Mesoderm, and ectoderm, Produce thin extracellular matrix (Basal Lamina), Some types can regenerate, some types are innervated |
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Term
| What epithelia is avascular? |
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Definition
| Linings of organs and skin |
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Term
| What epithelia is vascular? |
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Definition
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Term
| Two morphological subdividsions of basal lamina? |
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Definition
| Lamina Densa & Lamina Lucida |
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Term
| What distinguishes the lamina densa? |
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Definition
| Beneath epithelial cells and lamina lucida and comprised of laminin, Type 4 Collagen, Fibronectin, Proteoglycans, and Glycosaminoglycans. |
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Term
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Definition
| Projections of transmembrane proteins that shows as clear area |
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Term
| What is a basement membrane? |
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Definition
| Two adjascent basal lamina fused together. |
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Term
| How to epithelial cells attach to basal lamina? |
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Definition
| Via integrins (Proteins) that are attach to laminin molecules in basal lamina.. |
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Term
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Definition
| The spread of malignant cells through the basal lamina and into the tissues below.. (BL should normally not allow this) |
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Term
| 3 Types of Exocrine Cells? |
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Definition
| Merocrine (Merely the secretion), Apocrine (Part of cell), Holocrine (Whole cell) |
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Term
| What is a single cell exocrine cell? |
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Definition
| Goblet cell which is clear staining and secretes mucus into digestive/respiratory tracts. (Merocrine) |
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Term
| What ligands to Goblet cells recognize? |
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Definition
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Term
| What is most likely malignant in mammary glands? |
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Definition
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Term
| What is most likely malignant in prostate glands? |
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Definition
| Acinar cells (Not the duct) |
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Term
| What color do mucus vs. serous acini stain? |
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Definition
| Mucous stain light and serous stain dark. |
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Term
| What are serous demilunes? |
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Definition
| Serous cells that get into mucous acini and are forced to the outside. |
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Term
| List common multicellular endocrine glands |
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Definition
| Adrenal, Gonads, Thyroid, Parathyroid, and Pituitary |
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Term
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Definition
| Secrete product into intercellular space to influence neighboring cells. (Gastrin secreted to stimulate parietal cells to secrete HCL) |
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Term
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Definition
| Change in structure and fxn to adapt to a changing local environment |
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Term
| What is diffuse neuroendocrine system (DNES) |
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Definition
| secrete peptide hormones/biogenic amines and act on cells in local area and found in variety of locations.. (Commonly liked with epithelial tissues) |
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Term
| What are myoepithelial cells? |
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Definition
| Stellate/Spindle shaped cells surround acini of multicellular glands to expel products.. between basal lamina and acini and rarely found in malignant cells. (If found, you can assume not malignant) |
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Term
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Definition
| Cancers of epithelial origins |
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Term
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Definition
| Cancer derived from glandular epithelium |
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Term
| Can epithelial tumors be identified? |
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Definition
| Via presence of cytokeratins |
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Term
| What is most common type of cancer? |
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Definition
| In adults, of epithelial origin (90%) and in children it's the opposite. |
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