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Epithelium
Some cards on the histological features of epithelium
28
Histology
Graduate
01/30/2015

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Cards

Term
True or false: Epithelium is highly vascular tissue
Definition
False. It is avascular.
Term
Name the three typical "shapes" for epithelial tissue
Definition
Squamous = Flat
Cuboidal = mostly square
Columnar = Taller than it is wide
Term
What type of epithelia does not have an apical free surface, and what types of tissues can it be found?
Definition
Epithelioid tissue

IT can be found in endocrine glands like the adrenal gland, anterior pituitary, or in islets of Langerhands

They are found in Epitheloreticular cells of thymus,

and epithelium derived from epithelial tumors (ex: epithelial ovarian carcinoma)
Term
What types of cells line the kidney tubules?
Definition
Simple Cuboidal Epithelium
Term
What types of cells line small ducts of exocrine glands like the pancreas?
Definition
Simple Cuboidal epithelium
Term
What types of cells do you find lining large ducts in exocrine glands?
Definition
Stratified cuboidal epithelium.
Term
Describe the function of simple columnar epithelium found in the cornea of the eye
Definition
It serves a sensory function
Term
True or false: in pseudostratified columnar epithelium, all cells reach the apical lumen
Definition
False. But all cells DO reach the basement membrane.
Term
What is the primary protein that makes up microvilli?
Definition
Actin
Term
Regarding movement, which epithelial modifications are motile, and which ones are not?
Definition
Non-motile: microvilli and Stereocilia

Motile: Cilia
Term
What is the primary component of cilia and describe the arrangement
Definition
They are made of microtubules arranged in pairs in a clockwise 9+2 configuration.
Term
What molecular motors move along microtubules?
Definition
Kinesis and dyneins
Term
What molecular motors move alone actin filaments?
Definition
Myosin
Term
What is the Zonula occuldens?
Definition
They are made up of tight junctions to neighboring cells prevent leakage between them.
Term
What is the zonula adherens?
Definition
These have actin bundles that attach one cell to another
Term
What is the macula adherens?
Definition
This is where desmosomes are found. They join the intermediate filaments of one cell to those of their neighbor
Term
What is a hemidesmosome?
Definition
It anchors epithelia to the basal lamina
Term
What is a gap junction?
Definition
This allows the passage of small water-soluble ions and molecules.
Term
What makes up a desmosome?
Definition
They are made up of tonofilaments
Term
In the Zonula occludens, what proteins are you likely to find?
Definition
occludin, claudins, junctional adhesion molecules (JAM)
Term
What protiens are you likely to find in the Zonula adherens?
Definition
Cel adhesion molecules (CAM) Cadherins, integrins, selectins, and immunoglubulin superfamily
Term
How does clostrium perfringens attack epithelial cells?
Definition
They bind to claudin in the zonulua occludens
Term
How does Helicobacter pylori attack epithelial cels?
Definition
They bind to zonula occludens molecules which causes damage to the protective layer of the stomach.
Term
Describe Merocine secretion
Definition
Membrane bound vesicles
Term
Describe Apocrine secretion
Definition
The secreted material is surrounded by cytoplasm and a plasma membrane. Ex: apocrine sweat glands
Term
Describe holocrine secretion
Definition
The whole cell is extruded. Example: sebacious glands
Term
Describe the three types of secrtions
Definition
Mucous: viscous and slimy. water soluble. Lost during tissue preparation

Serous: Watery, but secretory granules are well preserved

Mixed: Contain both types of secretory cells
Term
What is found in the basal domain of epithelial cells?
Definition
Hemidesmosomes and focal adhesions
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