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Epidemiology
Sultana Quiz 2
27
Science
Post-Graduate
10/28/2011

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Term
Epidemiology study design
Definition
1. Experimental studies
or Clinical trial

2. Observational study
Term
. Experimental
Definition
study factor is manipulated by the investigator.
Term
Observational -
Definition
no manipulation of study factor by the investigator
1. Descriptive versus Analytic
2. Retrospective versus Prospective
Term
Epidemiologic study designs (Observational study)
Definition
1. Prospective or Cohort study

2. Retrospective or Case control study

3. Cross sectional or Prevalence study
Term
Observational study
Definition
1. DESCRIPTIVE EPIDEMIOLOGY


2. ANALYTIC EPIDEMIOLOGY
Term
Descriptive epidemiology
Definition
seeks to measure the frequency in which diseases occur or collect descriptive data on possible causal factors.
Term
Analytic epidemiology:
Definition
attempts to specify in more detail the causes of a particular disease”
Term
- Descriptive: Most basic demographic studies
Definition
a. * cross-sectional
                   (a snapshot;)
Term
Analytical: Comparative studies testing an hypothesis.
Definition
A. * cohort
                   (prospective; cause-and-effect relationship can be inferred)
                B.* case-control
                   (retrospective; cause-and-effect relationship can be inferred)
Term
* Cohort (prospective
Definition
Begins with an exposure (smokers and non-smokers)
Term
Case-control (retrospective )
Definition
Begins with outcome (cancer cases and healthy controls)
Term
DESCRIPTIVE EPIDEMIOLOGY
Definition
Examining the distribution of a disease in a population, and observing the basic features of its distribution in terms of time, place, and person.
Term
Typical study design:DESCRIPTIVE EPIDEMIOLOGY
Definition
community health survey (approximate synonyms - cross-sectional study, descriptive study)
Term
ANALYTIC EPIDEMIOLOGY
Definition
Testing a specific hypothesis about the relationship of a disease to a putative cause, by conducting an epidemiologic study that relates the exposure of interest to the disease of interest.
Term
ANALYTIC EPIDEMIOLOGY
Typical study designs:
Definition
cohort, case-control
Term
THE THREE ESSENTIAL CHARACTERISTICS OF DISEASE WE LOOK FOR IN DESCRIPTIVE EPIDEMIOLOGY:
Definition
TIME
PLACE
PERSON
Term
Time
Definition
Changing or stable?
Seasonal variation.
Clustered (epidemic) or evenly distributed (endemic)?
Point source or propagated.
Term
Place
Definition
Geographically restricted or widespread (pandemic)?  
Relation to water or food supply.  
Multiple clusters or one?
Term
Person
Definition
Age
Socio-economic status
Gender
Ethnicity/Race
Behavior
Term
To undertake an analytic epidemiologic study you must first:
Definition
Know where to look
Know what to control for
Be able to formulate hypotheses compatible with laboratory evidence
Term
THE THREE PHENOMENA ASSESSED IN ANALYTIC EPIDEMIOLOGY ARE:
Definition
HOST
AGENT
ENVIRONMENT
Term
Agents
Definition
Nutrients
Poisons
Allergens
Radiation
Physical trauma
Microbes
Psychological experiences
Term
Host Factors
Definition
Genetic endowment
Immunologic state
Age
Personal behavior
Term
Environment
Definition
Crowding
Atmosphere
Modes of communication
Term
Modes of communication
Definition
phenomena in the environment that bring host and agent together, such as:
Vector
Vehicle
Reservoir
Term
Cohort study/ Incidence study
Definition
This study is also known as a longitudinal or incidence study design.
Term
A cohort is
Definition
group of people who are either of the same age or share some other common characteristics
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