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Endocrinology- 3. Homeostasis
Basic principles of body equiligbrium
5
Medical
Undergraduate 4
02/17/2010

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Term
Homeostasis
Definition
state of equilibrium in the body with respect to various functions and to
the chemical composition of fluids and tissues
Term
Regulatory System
Definition
1. detector (of an imbalance)
2. coupling mechanism (activates secretory apparatus)
3. hormone secretory apparatus
4. hormone
5. end-organ capable of responding to the hormone
6. detector (to recognize hormonal effect has occurred)
7. mechanism for hormone removal (from target cells, blood)
8. synthetic apparatus (to replenish hormone in secretory cell/apparatus)
Term
Negative Feedback
Definition
decrease in a level leads to increase in another, or vice-versa
1. controlled variable  sensor  comparator/set point  effector  variable
2. Deviations from Constancy: changing environment (adjust by temporarily
changing the set point or producing a signal that overrides it)
Term
Positive Feedback
Definition
some consequence of hormonal secretion acts on hormonal secretory
cells to provide enhanced drive for hormonal secretion (ex.: oxytocin)
Term
Hormones & homeostasis
Definition
Most endocrine responses are dependent on very small concentrations of hormones.
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