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Endocrinology
N/A
13
Medical
Professional
01/28/2011

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Term
Chemical Class of Somatotrophin(STH)
Definition

PPP

(Portein, Polypeptide, Peptide)

Term
Site of synthesis of Somatotrophin
Definition
Somatotorphe cells (= Adenohypophysis)
Term
Primay function of Somatotrophin(STH)
Definition
Increase linear height
Term
Means of Somatotrophin
Definition
1. Stimulate the enzymes of protein
- anabolism(syntheis)
2. Stimulate the synthesis of Somatomedin(SM)

* STH doesn't directly cause bones to grow.
Somatomedin causes bones to grow.
Term
Secondary Function of Somatotrophin (STH)
Definition

1. Stimulate Metabolism

2. Increase blood glucose

3. Increase blood pressure

4. Increase plasma calcium

5. Increase renal reabsorption of sodium and phosphrous

6. Increase immune response

7. Increase oxygen transport

8. Stimulate breast development

9. Increase milk production(lactation)

Term
What are the means of Somatotrophin to stimulate metabolism?
Definition
  1. Stimulate the enzymes of protein anabolism
  2. Stimulate the enzymes of CHO catabolism
  3. Stimulate the enzymes of lid catabolism
Term
What are the means of STH to increase blood glucose?
Definition
  1. Stimulate the synthesis of Glucagon
  2. Stimulate the synthesis of Cortisol
  3. Stimulate the enzymes of CHO catabolism
  4. Act as an insulin antagonist
Term
What are the means of STH to increase blood pressure?
Definition

increase the number of solutes in plasma causing the body to passively absorb water from the ISF to increase the plasma volume

Term
What is the means of STH to increase plasma calcium?
Definition
Increase intestinal absorption of calcium
Term
What is the means of STH to increase the renal absorption of sodium and phospherous?
Definition

increase cell membrane  permeability to sodium and phosphorus from DCT & CD

 

*DCT=Distal convalated tubule

*CD=Collecting Duct

Term
What is the site for synthesis of thyroxines?
Definition
T4; active follicle
T3; active follicle, liver, plasma as a result of "Deiodination of T4(removing an iodine from T4)"
Term
What is the chemical class of T4?
Definition
Biogenic Amine-Diaminoacid Derivative
Term
Whatis the name of true thyroxine?
Definition
Tetraiodothyronine
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