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Endocrinology Pancreas 3
Endocrinology Pancreas 3
9
Science
Undergraduate 4
04/23/2009

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Term
Insulinoma
Definition
an inulin secreting tumor in the pancreas
Term
What are the causes of Insulinoma?
Definition
High insulin levels may lead to hypoglycemia. leading to anzxiety and hunger. If severe leads to coma and death. VERY RARE. Most are NOT cancer.MEN1 at high risk for Insulinomas.
Term
What are the symptoms of Insulinoma?
Definition
sweating, tremor, rapid heart rate, anxiety, hunger, dizziness, headache, clouding vision, confusion, behaviooural changes, convulsions, loss of consciousness.
Term
What are the signs and tests for insulinoma?
Definition
Person's blood may be tested while fasting. Low blood glucose, high serum insulin level, high C-peptide level.
Term
Signs and tests for Insulinoma
Definition
person's blood may be tested while fasting. may have: low blood glucose, high serum insulin level, high C-peptide level.
CT scan MRI. Endoscopic ultrasound. Octreotide scan. Pancreatic arteriography. Pancreatic venous sampling for insulin.
Term
What is the treatment for insulinomas?
Definition
Surgery is the preferred treatment. Multiple tumors may require partial removal of the pancreas. At least 15% of the pancreas is left to prevent nutrient malabsorption from lack of pancreatic enzymes. Diazoxide may be given to lower insulin secretion and avoid hypoglycemia.
Term
What does the drug diazoxide do?
Definition
It is given when treating insulinomas to help lower the innsulinn secretion.
Term
What is the prognosis for Insulinomas?
Definition
Most are benign and surgery is effective. Severe hypoglycemic reaction or the spread of cancerous tumors to other organs can be fatal.
Term
What are complications wiht insulinomas?
Definition
Severe hypoglycemic reaction, cancerous tumor spreading.
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