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Endocrine
Pharmacology
41
Pharmacology
Graduate
01/17/2014
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Term
acromegaly tx
 Definition
octerotide
Term
glucagonoma tx
 Definition
somatostatin (octreotide)
Term
stimulate labor, uterine contractions
 Definition
oxytocin
Term
addison's disease tx
 Definition
glucocorticoids
Term
iatrogenic cushings as side effect
 Definition
glucocorticoids
Term
osteoporosis SE
 Definition
glucocorticoids
Term
thin skin and easy bruisibility SE
 Definition
glucocorticoids
Term
adreanl atrophy SE
 Definition
glucocorticoids
Term
peptic ulcers SE
 Definition
glucocorticoids
Term
diabetes as SE
 Definition
glucocorticoids
Term
long acting glucocorticoids
 Definition
dexamethasone and beclomethasone
Term
PTU vs methimazole
 Definition
PTU = both peroxidase and 5'-deiodinase
Methimazole = only peroxidase
Term
agranulocytosis
 Definition
PTU and methimazole
Term
aplastic anemia
 Definition
PTU and methimazole
Term
PTU or mehtimazole in pregnancy?
 Definition
PTU
Term
rapid-acting insulin
 Definition
lispro and aspartate
Term
long acting insulin
 Definition
glargine, detemir
Term
toxicities of insulin
 Definition
hypoglycemia, lypodystrophy, weight gain
Term
second gen SU
 Definition
glyburide, glimepiride, glipizide
Term
close K channel in beta cell leading to depolarization -> triggering insulin release
 Definition
SU
Term
disulfiram like effects
 Definition
first gen SU
Term
decrease gluconeogenesis
 Definition
metformin
Term
increases insulin sensitivity
 Definition
metformin, TZD
Term
binds PPAR-gama
 Definition
TZDs
Term
first line therapy for DM
 Definition
metformin
Term
lactic acidosis
 Definition
metformin
Term
CI if Cr > 1.5
 Definition
metformin
Term
hepatotoxic
 Definition
TZDs
Term
CI in heart failure
 Definition
TZDs
Term
inhibit brush border alpha glucosidases
 Definition
acarbose miglitol
Term
decrease postprandial glucose
 Definition
alpha-glucosidase inhibitors
Term
GI disturbances
 Definition
alpha-glucosidase inhibitors, metformin
Term
decreases glucagon
 Definition
pramlintide, GLP1, DPP4 inhibitors
Term
increases insulin secretion
 Definition
SU, GLP1 and DPP4 inhibitors
Term
pancreatitis
 Definition
GLP1
Term
biguanide
 Definition
metformin
Term
TZD
 Definition
pioglitaone, rosiglitazone
Term
increase risk of MI
 Definition
rosiglitazone
Term
GLP1 analog
 Definition
exenatide, lyraglutide
Term
DPP4 inhibitors
 Definition
gliptins
Term
delays gastric emptying
 Definition
DPP4 inhibitors
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