Term
| Why are thyroid levels so critical in developing child? |
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Definition
| Hypothyroid during development can cause severe mental retardation |
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Term
| What are some drug interactions seen with thyroid replacement |
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Definition
Thyroid hormone: Increases catabolism of digitalis and Vit K-Dep Factors(increasing anti-coagulant action)
Amiodarone-Hypo or sometime Hyperthyroid
Phenytoin, Rifampin, Carbamazepine increase thyroid catabolism |
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Term
| What are the treatment options for Hyperthyroid and when would each be used? |
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Definition
131 iodination/Thyroidectomy: adult
Thioureas: Kids or Pregnant |
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Term
| What are the complications of the different treatments of Hyperthyroid |
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Definition
131 or Thyroidectomy: Thyroxine requiring hypothyroidism
Thioureas: Skin Rash, Goiter |
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Term
| What is the treatment of choice for a pregnant women who is hyperthyroid |
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Definition
PTU during first trimester because it does not cross the plecental/ breast milk barrier as readily as methimazole
Methimazole for 2nd and 3rd |
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Term
| How would you treat a patient after exposure to radioactive iodide? |
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Definition
| High dose Iodide to dilute the concentration in the thyroid |
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Term
| What drugs are typically used in the treatment of Thyrotoxicosis? |
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Definition
| Beta-blockers: Propranolol(good CNS penetration), Esmolol(Acute Thyroid Storm) |
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