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Endocrine Pharm1
HypoT and Pituitary hormones/effects
25
Medical
Professional
04/18/2013

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Cards

Term
Somatotropin
Definition
RECOMBINANT hGH Anabolic increases GHRH, decreases somatostatin

induces somatomedins

SE = headaches
Term
Somatrem
Definition
derivative GHRH that induces somatmedins and decreases somatostatin

SE = headaches
Term
Sermorelin Acetate
Definition
synthetic somatropin fragment less effective than somatropin
Term
Mecasermin
Definition
recombinant insulin growth factor for larons syndrome

hypoglycemia, intracranial hypertension
Term
Octreotide
Definition
SOMATOSTATIN ANALOG THAT Decreases GH secretion and tumor size in AGROMEGALY

SE = gall stones
Term
Sandostatin LAR
Definition
somatostatin analog
Term
Pegvisomant
Definition
GH ANTAGONIST

only treats side effects of tumor, doesnt inhibit GH secretion (no delta)
SE = abnormal LFTS
Term
Bromocriptine (Endocrine)
Definition
D2 agonist for prolactinemia
Term
Pergolide (endocrine pharm)
Definition
Da receptor agonist for prolactinemia
Term
Gonadorelin Acetate
Definition
Treatement decreased gonadotropin production in pulsitile

SE = multiple births
Term
Ketoconazol (endocrine)
Definition
cortisol excess cushings disease

hepatic dysfunctino and interacts antihistamines
Term
cortisol (endocrine)
Definition
addisons replacement
Term
desmopressin
Definition
diabetes insipidus
(long lived vasopressin analog)
Term
thiazide diuretics (endocrine pharm)
Definition
Treatment for nephrogenic diabetes insipitus (no one knows whys)
Term
demeclocycline
Definition
SIADH - inhibits response to ADH in collecting duct
Term
PITOCIN
Definition
artificial oxytocin to induce labor
Term
Atosiban
Definition
supression of preterm labor (oxytocin antagonist)
Term
gonadatropins/menotropins
Definition
Mimimic LH/FSH from urine of post menopausal women
Term
levothyroxine sodium
Definition
T4 sodium - prolonged duration
Term
liothyroxine sodium
Definition
T3
too much induces osteoporosis
Term
liotrix
Definition
T4 and T3 combined
Term
propylthiouracil
Definition
inhibits T4-T3 conversion and thyroid peroxidase
Term
methimazole
Definition
inhibits thyroid peroxidase
Term
Iodide, Na Ipodate
Definition
ionated contrast agent, short term anti-thyroid that inhibits T4-T3 conversions

Thyroid storm
Term
131 I
Definition
Local radation - thyroid-cytotoxic
contraindicated in younge or pregnant
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