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Definition
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coronary heart disease
type 2 diabetes
cancer (endometrial, breast, and colon)
hypertension
dyslipidemia
stroke
liver and gallbladder disease
sleep apnea and respiratory problems
osteoarthritis
gynecological problems |
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Definition
| health consequences of obesity |
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Term
abdominal obesity, given as waist circumference: women > 35 in, men > 40 in
triglycerides: > 150 mg/dL
HDL: women < 50 mg/dL, men < 40 mg/dL
blood pressure: >/= 130/85 mmHg
fasting glucose: >/= 110 mg/dL |
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Definition
metabolic syndrome: a cluster of risk factors that increase risk of cardiovascular disease
what are the risk factors and their defining levels? |
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Term
genetics
environmental
physiological (neuro) |
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Definition
| what causes can contribute to obesity/overweight? |
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Term
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Definition
| what is the primary neuropeptide controlling the hedonic aspects processed in the limbic area of the brain? |
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Term
REDUCE body weight: 5-10%; studies show that even modest weight reduction of 5-10% can greatly decrease risk of obesity-associated risk factors
MAINTAIN lower body weight long term
PREVENT further weight gain |
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Definition
| goals of obesity treatments |
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Term
increased secretion/reuptake inhibitor of NE
ADRs: abuse potential, sleepiness
contraindications: CVD, HTN, hyperthyroidism, MOAi |
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Definition
| MOA, side effects, and contraindications of phenterimine (Adipex) |
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Term
MOA: increase secretion/reuptake inhibitor of NE
ADRs: abuse potential, sleepiness
CI: CVD, HTN, hyperthyroidism, MOAi |
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Definition
| MOA, side effects, and contraindications of diethylpropion(Tenuate) |
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Term
BMI >/= 30
BMI 27-29.9 with risk factors and comorbidities: HTN, dyslipidemia, CHD, DM2, sleep apnea
lack of RCT showing one agent is more effective vs. another: patient preference, comorbidities, cost
to day no long term data on morbidity and mortality end points |
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Definition
| when is medication indicated for obesity? |
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Term
vitamin B1 (thiamine) deficiency:
vitamin B12
iron: most iron absorption occurs in the lower stomach which is bypassed with R-en-Y procedure; monitor iron levels; gluconate salt may be better than sulfate
calcium and vitamin D: calcium citrate preferred salt for supplementation |
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Definition
| vitamin and mineral deficiencies that may result from gastric bypass |
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