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Endocrine/Nutrition Exam 1 Petkewicz
Endocrine/Nutrition Exam 1 Petkewicz
14
Pharmacology
Graduate
10/27/2010

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Cards

Term
18.5-24.9
Definition
healthy weight BMI
Term
25.0-29.9
Definition
overweight BMI
Term
30.0-34.9
Definition
Class I obesity BMI
Term
35.0-39.9
Definition
Class II obesity BMI
Term
>/= 40.0
Definition
Class II obesity BMI
Term
coronary heart disease
type 2 diabetes
cancer (endometrial, breast, and colon)
hypertension
dyslipidemia
stroke
liver and gallbladder disease
sleep apnea and respiratory problems
osteoarthritis
gynecological problems
Definition
health consequences of obesity
Term
abdominal obesity, given as waist circumference: women > 35 in, men > 40 in
triglycerides: > 150 mg/dL
HDL: women < 50 mg/dL, men < 40 mg/dL
blood pressure: >/= 130/85 mmHg
fasting glucose: >/= 110 mg/dL
Definition
metabolic syndrome: a cluster of risk factors that increase risk of cardiovascular disease
what are the risk factors and their defining levels?
Term
genetics
environmental
physiological (neuro)
Definition
what causes can contribute to obesity/overweight?
Term
dopamine
Definition
what is the primary neuropeptide controlling the hedonic aspects processed in the limbic area of the brain?
Term
REDUCE body weight: 5-10%; studies show that even modest weight reduction of 5-10% can greatly decrease risk of obesity-associated risk factors
MAINTAIN lower body weight long term
PREVENT further weight gain
Definition
goals of obesity treatments
Term
increased secretion/reuptake inhibitor of NE
ADRs: abuse potential, sleepiness
contraindications: CVD, HTN, hyperthyroidism, MOAi
Definition
MOA, side effects, and contraindications of phenterimine (Adipex)
Term
MOA: increase secretion/reuptake inhibitor of NE
ADRs: abuse potential, sleepiness
CI: CVD, HTN, hyperthyroidism, MOAi
Definition
MOA, side effects, and contraindications of diethylpropion(Tenuate)
Term
BMI >/= 30
BMI 27-29.9 with risk factors and comorbidities: HTN, dyslipidemia, CHD, DM2, sleep apnea
lack of RCT showing one agent is more effective vs. another: patient preference, comorbidities, cost
to day no long term data on morbidity and mortality end points
Definition
when is medication indicated for obesity?
Term
vitamin B1 (thiamine) deficiency:
vitamin B12
iron: most iron absorption occurs in the lower stomach which is bypassed with R-en-Y procedure; monitor iron levels; gluconate salt may be better than sulfate
calcium and vitamin D: calcium citrate preferred salt for supplementation
Definition
vitamin and mineral deficiencies that may result from gastric bypass
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