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Endocarditis
Therapeutics (V) exam 3
29
Other
Not Applicable
01/22/2013

Additional Other Flashcards

 


 

Cards

Term
Common pathogens of Endocarditis
Definition
  1. Staph
  2. Strep
  3. Enterococcus
Term
Endocarditis stigmatas
Definition
  • Janeway lesions
  • Splinter hemmorhages
  • Clubbing of fingers
  • Osler nodes
  • Roth spots
  • Emboli
Term
Which pathogens contribute to more severe endocarditis?
Definition
  • Fungi
  • Resistant organisms
  • <-> rods (pseudomonas)
Term

Treatment

  • Streptococcus
  • Native valve
  • High penicillin susceptible
Definition
  • Penicillin G 12 million U/24h X4W

or

  • Ceftriaxone X4W
Term

Treatment

  • Streptococcus
  • Native valve
  • High penicillin susceptible
  • (quick treatment)
Definition
  • Penicillin G 12 million U/24h IV X2W
  • or
  • Ceftriaxone X2W

+

  • Gentamicin X2W
Term

Treatment

  • Streptococcus
  • Native valve 
  • Relative penicillin susceptible
Definition
  • Penicillin G 24 million U/24h IV X4W
  • or
  • Ceftriaxone  X4W

+

  • Gentamicin X2W
Term

Treatment

  • Streptococcus
  • Prosthetic valve 
  • penicillin susceptible
Definition
  • Penicillin G 24 million U/24h IV X6W
  • or
  • Ceftriaxone X6W

+

  • Gentamicin X2W
Term

Treatment

  • Streptococcus
  • Prosthetic valve 
  • Relative penicillin susceptible
Definition
  • Penicillin G 24 million U/24h IV X6W
  • or
  • Ceftriaxone X6W

+

  • Gentamicin X6W
Term

Treatment

  • Staphylococcus
  • Absence of prosthetic materials
Definition
  • Nafcillin/Oxacillin X6W

+/-

  • Gentamicin sulfate 3mg/kg/24h IV X3-5D
Term

Treatment

  • Staphylococcus
  • Absence of prosthetic materials
  • nonanaphylactic Penicillin allergy
Definition
  • Cefazolin X6W

+/-

  • Gentamicin X3D
Term

Treatment

  • Staphylococcus
  • Absence of prosthetic materials
  • Oxacillin resistant
Definition
  • Vancomycin X6W
Term

Treatment

  • Staphylococcus
  • Prosthetic materials
Definition
  • Nafcillin/Oxacillin  X≥6W

+

  • Rifampin X≥6W

+

  • Gentamicin sulfate X2W
Term

Treatment

  • Staphylococcus
  • Prosthetic materials
  • Oxacillin resistant
Definition
  • Vancomycin X≥6W

+

  • Rifampin X≥6W

+

  • Gentamicin X2W
Term

Treatment

  • Enterococcus
Definition
  • Ampicillin X4-6W
  • or
  • Penicillin G 24-30 million U/24h IV X4-6W

+

  • Gentamicin X4-6W
Term

Treatment

  • Enterococcus
  • penicillin resistant
Definition
  • Vancomycin X6W

+

  • Gentamicin X6W
Term

Treatment

  • Enterococcus
  • Gentamicin resistant
Definition
  • Ampicillin X4-6W
  • or
  • Penicillin G 4-6W

+

  • Streptomycin X4-6W
Term

Treatment

  • Enterococcus
  • Gentamicin, penicillin resistant
Definition
  • Vancomycin X6W

+

  • Streptomycin X6W
Term

Treatment

  • Enterococcus faecium
  • Penicillin, aminoglycosides, vancomycin resistant
Definition
  • Linezolid X≥8W
  • Quinupristin-dalfopristin X≥8W
Term

Treatment

  • HACEK
Definition
  • Ceftriaxone X4W

or

  • Ampicillin X4W

or

  • Ciprofloxacin X4W
Term

Treatment

  • Bartonella suspected
Definition
  • Ceftriaxone X6W
  • Gent X2W
  • +/- Doxy X6W
Term

Treatment

  • Bartonella documented
Definition
  • Doxy X6W
  • Gent X2W
Term

Ceftriaxone

  • Dose
  • Who
Definition
  • 2g/24h IV/IM
  • Strep
Term

Pen G

  • Dose
  • Who
Definition
  • 12-24 million units/24h IV divided into 4-6
  • Strep, Enterococcus
Term

Gentamicin

  • Dose
  • Who
Definition
  • 3mg/kg IV/IM
  • Strep, Stapth, Enterococcus, Bartonella
Term

Nafcillin/Oxacillin

  • Dose
  • Who
Definition
  • 12g/24h IV divided 4-6
  • Staph
Term

 

Cefazolin

  • Dose
  • Who
Definition
  • 6g/24h divided 3
  • Penicillin allergic staph
Term

Rifampin

  • Dose
  • Who
Definition
  • 900mg/24h IV/PO divided 3 (≥6W)
  • Prosthetic staph
Term

Ampicillin

  • Dose
  • Who
Definition
  • 12g/24 divided 6 (4-6W)
  • Enterococcus
Term

Streptomycin

  • Dose
  • Who
Definition
  • 15mg/kg /24 IV/IM divided 2
  • Enterococcus resist Gent
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