| Term 
 
        | Growth Hormone Treat grwth horm def or inadeq grwth horm secr |  | Definition 
 
        | Humatrope hypercalciuria (risk renal calculi→kidney stns); 3-5”/2 yrs
 |  | 
        |  | 
        
        | Term 
 
        | ADH-Antiduretic Hormone Treat Diabetes Insipidus (excessive thirst & urination w/dilute urine)
 |  | Definition 
 
        | Desmopressin Vasopressin
 ↑BP, fl ret; daily wt; strict I&O
 |  | 
        |  | 
        
        | Term 
 
        | Thyroid Hormones Treat Hypothyroidism
 |  | Definition 
 
        | Synthroid ↓wt, diarrhea, tachycardia
 Monitor toxicity/overdose
 |  | 
        |  | 
        
        | Term 
 
        | Antithyroid Meds Treat Hyperthyroidism
 |  | Definition 
 
        | PTU Tapazole
 Iodine
 ↑ wt, const, bradycardia
 Monitor toxicity/overdose
 |  | 
        |  | 
        
        | Term 
 
        | Mineralcorticoids Treat adrenal gland failure or hyposecretion; retain Na+ & water, release K+
 |  | Definition 
 
        | Fludrocortisone Na+ & fl ret; immunosupp; Dose slowly tapered; eat K+ rich foods
 |  | 
        |  | 
        
        | Term 
 
        | Glucocorticoids Treat Addison’s disease (↓cortisol or ACTH); ↑carb, protein, fat metabolism
 |  | Definition 
 
        | Cortisone Na+&fl ret; immunosuppr,Cushingoid Syn
 |  | 
        |  | 
        
        | Term 
 
        | ACTH - Adrenocorticotropin Hormone Treat Addison’s disease (↓secretion of cortisol or ACTH)
 Enhance secr ACTH
 |  | Definition 
 
        | Corticotropin Na+ & fl ret; immunosuppr
 |  | 
        |  | 
        
        | Term 
 
        | Ca Citrate (Citracal) Treat mild hypocalcemia &
 suppl dietary Ca
 |  | Definition 
 
        | Calcium Citrate (Citracal) |  | 
        |  | 
        
        | Term 
 
        | Vitamin D Treat hypocalcemia or vit D def
 |  | Definition 
 
        | Calcitrol Adv: hypercalcemia (ataxia, irritable, szs, tinnitus, HTN)
 |  | 
        |  | 
        
        | Term 
 
        | Insulin Treats Type I & Diabetic Ketoacidosis; corrects hyperglycemia by restoring ability of cells to use glucose
 |  | Definition 
 
        | Interacts: ASA, alc, beta blkrs, corticosteroids, |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | ↓60 mg/dl→irritable, h/a, hunger, tachycardia, diaphoresis |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Humalog, Novolog O=15-30m
 P=1-1.5h
 D=3-4h
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Regular, Humulin R, Novolin R O=30m-1h
 P=2-3h
 D=4-6h
 |  | 
        |  | 
        
        | Term 
 
        | Insulin Intermediate-Acting |  | Definition 
 
        | NPH, Lente O=2-4h
 P=4-12h
 D=16-20h
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Ultralente, Lantus, Levemir O=1h
 P=none
 D=24h
 |  | 
        |  | 
        
        | Term 
 
        | Oral Antidiabetic Agents Treat Type 2 Diabetes Mellitus; Helps pancreas produce more insulin
 |  | Definition 
 
        | Interacts: alc, beta blkrs, corticosteroids, coumadin |  | 
        |  | 
        
        | Term 
 
        | Oral Antidiabetic Agents Sulfonylureas: stimulate rel insulin from Islets of Langerhans/Pancreas
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Oral Antidiabetic Agents Biguanide: ↓ prod glucose by liver = ↓blood glucose
 |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Oral Antidiabetic Agents Α-Glucosidase Inhibitors: delay absor carbs = ↓blood glucose
 |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | ↑250 mg/dl→lethargic, flushed, deep respir (Kussmaul), fruity breath |  | 
        |  | 
        
        | Term 
 
        | Glucose Elevating Meds Promotes breakdown glycogen, ↓glycogen synthesis, stim synthesis glucose
 Emer treat severe hypoglycemia
 |  | Definition 
 
        | Glucagon Absorbed rapidly (PO, SC, IV)
 Table sugar avoided
 |  | 
        |  | 
        
        | Term 
 
        | Estrogens Menopause & Osteoporosis
 Hormone replacmt therapy (HRT)
 |  | Definition 
 
        | Estrace ↑skin pigment, ↑wt, fl ret, h/a, HTN, breast tender, chg in libido; Ck s/s thromboembolism→calf tender, redness, warmth; CK s/s pulmonary embolism→SOB, chest pain, anx; Inj-deep IM
 |  | 
        |  | 
        
        | Term 
 
        | Progestins Treat amenorrhea, breast & renal cancer; post-menop syn
 Chgs endometrium in prep implant embryo
 |  | Definition 
 
        | Depo-Provera Norplant
 Bkthru bldg, spotting, altered menst flow, amenorrhea, breast tender, galactorrhea, vag candidiasis, acne, ↑wt; Ck s/s thromboembolism & pul embolism
 |  | 
        |  | 
        
        | Term 
 
        | Oral Contraceptives ↓ incidence of ovulation to prevent conception
 |  | Definition 
 
        | GI Upset, acne, h/a, dizzy, ↓libido, fl ret, edema; Interacts: antibiotics, anticonvul, anticoag, alc; ↑risk thromboembolism→calf tender, redness, warmth |  | 
        |  | 
        
        | Term 
 
        | Oral Contr - Monophasic: Same amt estrogen & progestin @ pill |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Oral Contr - Biphasic: Fixed estrogen dose + low progestin dose @ pill |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Oral Contr - Triphasic: 3 diff estrogen & progestin doses thruout pill pack |  | Definition 
 
        | Ortho-Novum 777 Tri-Levlen
 |  | 
        |  | 
        
        | Term 
 
        | Fertility Medications Stim ovulation or follicular maturation
 |  | Definition 
 
        | Clomid ↑HR, DVT, ovarian hyperstimulation; self-admin drugs
 |  | 
        |  | 
        
        | Term 
 
        | Uterine Stimulants aka “Oxytocics”; Induce labor, enhance labor
 |  | Definition 
 
        | Oxytocin (Pitocin) ut cramp, ↓HR fetus, postpartum hemorrhage; Toxicity: ut rupture; ↑risk hyperbilirubinemia newborn
 Monitor contractions & cervical dilation & fetal HR/BP
 |  | 
        |  | 
        
        | Term 
 
        | Uterine Relaxants Aka “Tocolytics”
 Inhibit contractions preterm labor
 |  | Definition 
 
        | Terbutiline Sulfate maternal & fetal palpitations, tachycardia, tremors; Position pt left lateral recumbent ↓hypotension & ↑renal blood flow
 Monitor ut act & fetal HR during IV
 |  | 
        |  | 
        
        | Term 
 
        | Ergot Alkaloids Control post-partum hemorrhage
 |  | Definition 
 
        | Ergonovine ↑BP, ut cramp, ↓ milk; no smoking (↑vasoconstriction); explain med purpose
 |  | 
        |  | 
        
        | Term 
 
        | Prostaglandins Terminate preg 12th wk - 2nd trimester
 |  | Definition 
 
        | Dinoprostone N/V/D, ut cramp
 |  | 
        |  | 
        
        | Term 
 
        | Peripheral Vasodilators Male pattern baldness/alopecia
 |  | Definition 
 
        | Rogaine Tachycardia, fl ret, ↑wt
 |  | 
        |  | 
        
        | Term 
 
        | Anabolic Steroids Dev to replace androgens; enhance perform athletes |  | Definition 
 
        | Androl-50 Female: ↓voice, male pattern hair distr, menses irregular, acne, ↑libido, ↑clitoris Male: gynecomastia, priapism, ↑libido, oligospermia Children: retarded growth, premature closure growth plate, precocious puberty NC: Monitor for hepatoxicity, daily wt
 |  | 
        |  | 
        
        | Term 
 
        | Medications for Erectile Dysfunction ↑corpus cavernosus arterial inflow & ↓venous outflow, resulting in erection |  | Definition 
 
        | Viagra Vardenafil
 priapism, excess sexual stim DO NOT TAKE w/ drugs w/ nitrates; 1 hr b/f sex
 |  | 
        |  | 
        
        | Term 
 
        | Meds Benign Prostatic Hyperplasia (BPH) Blk alpha 1 receptors prostate→relax sm muscles, improve urine flow & ↓symptoms BPH
 Aka 5α-Reductase Inhibitors
 |  | Definition 
 
        | Proscar Flomax
 impotence, ↓libido, ↓semen vol, hypotension; RO prostate cancer b/f therapy, monitor BP, urine vol
 |  | 
        |  | 
        
        | Term 
 
        | Oral contraceptives: other preps |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Magnesium Sulfates Stop preterm labor & prevent seizures with preeclampsia & eclampsia
 |  | Definition 
 
        | Magnesium Sulfate Drowsy, ↓deep tendon reflex, ↓hand grasp, N/V, hyponatremia
 Monitor hand grasp, deep tendon reflex, RR, serum Mg, monitor IV extravasation
 |  | 
        |  |