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emotional reaction to the reproductive cycle
R-GU II
27
Medical
Graduate
10/29/2010

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Term
do estrogen/progesterone affect the NTs?
Definition
yes estrogen/progesterone can affect nor-epinephrine, serotonin, dopamine, GABA, histamine
Term
t/f, women are more affected by emotions than men?
Definition
t, women are very profoundly influenced by mood regulatory mechanisms within hypothalamus (more prone to depression/SADD/anxiety). male behavior is regulated more extra-cerebrally (more prone to alcohol abuse/dependence, anti-social behavior).
Term
what % of women have insomnia around in their premenstrual time?
Definition
75%
Term
what is premenstrual syndrome (PMS)?
Definition
changes in emotion occurring in the late luteal phase which affect cognitive ability and are associated w/somatic complaints - sometimes to the point where they *interfere w/the person's daily life*. these include: irritability, depression, anger, fatigue, changes in libido, sensation of abdominal bloating, and menstrual cramps. w/in 1-2 days, once menstrual flow starts, these symptoms will abate (until the next month).
Term
what is premenstrual dysmorphic disorder (PMDD)?
Definition
similar to PMS symptoms, but more severe with irritability/anxiety being the most prominent. depression, labile effect, changes in appetite, loss of interest in normally appealing things, and the somatic symptoms: headaches/abdominal bloating/breast tenderness all may occur. PMDD is differentiated from basic personality traits as these symptoms do disappear w/oophorectomy. this is more rare, affecting ~ < 8% of women.
Term
what is the difference between PMS and PMDD?
Definition
in PMDD, daily function becomes very impaired (hard time attending school, work, usual family responsibilities) - but both are associated w/the late luteal stage of the menstrual cycle.
Term
what is tx for PMDD?
Definition
*emotional tx: anti-depressants (SSRIs), short acting tranquilizers, short-term diuretic use (effective, but MOA unknown), and temporary stimulant use. *somatic tx: NSAIDs, OCPs, OMM (sacral inhibition), acupressure
Term
what is the internal emotional reaction in pregnant women (when she knows she's going to be a mother)?
Definition
feelings of love/needing to be loved - which can affect her self-image. pregnancy can also carry many ambivalent/mixed feelings. this is a real adjustment process for women (dealing w/biological and emotional change). pregnant women are referred to as "expectant" (not just expecting to be a mother, expecting to have a child, but expecting all other issues that register).
Term
what may emotionally characterize the first trimester of pregnancy?
Definition
constant cramping and n/v may discourage the woman from her enthusiasm for motherhood.
Term
what may emotionally characterize the second trimester of pregnancy?
Definition
the woman has the outer appearance of pregnancy, can hear fetal heart sounds and see the baby on US - pregnancy becomes more of a reality.
Term
what may emotionally characterize the third trimester of pregnancy?
Definition
"it's time to give birth"
Term
can labor/delivery be complicated by the mother's apprehensions about it? what can help w/this?
Definition
yes - particularly apprehensions about the pain involved. coaching the mother on the labor process can help diminish this (better sense of pain control).
Term
as a mother holds her child for the first time, how could the fact the baby is not inside her anymore affect her?
Definition
she may experience a sense of loss
Term
what are some of the psychological changes associated w/childbirth?
Definition
an increased sense of anticipation, energy, some anxiety, and a sense of "what to do" after completing the challenge of delivery. 80% of women will show mood changes post-partum and 20% may meet criteria for a major mood disorder.
Term
what is the most common mood change after delivery?
Definition
baby blues, which occurs over the first 5 days post-partum, then tapers off over 2 wks. baby blues consist of a *transient sense of sadness, being wiped out and spontaneous tearing.
Term
what is post-partum depression? when can it start? symptoms? tx?
Definition
when baby blues becomes a deeper depression - likely related in a large part to difficulty w/sleep maintenance due to a sense of hypervigilance as the newborn calls for the mother at night. post-partum depression *may start as late as 12 wks.* symptoms: profound depression, inability to experience pleasure, anorexia, sleep problems, suicidal thoughts, difficulty summoning energy to take care of necessary tasks, feelings of guilt w/no reason, and obsessive fear about the baby's safety. best tx: sleep for mom
Term
what is post-partum psychosis?
Definition
the worst post-partum reaction, a very severe form of mental disorder which can start as soon as 2-3 days after delivery (risk extends up to 4 mos). post-partum psychosis involves an *inability to perceive reality, including hallucinations, mania (not depression), delusions (may involve baby, demons, aliens, etc), and is a great risk for mother/baby.
Term
what is the route by which changes in the brain effects changes in the rest of the body?
Definition
the HPA axis (hypothalamus – pituitary – adrenals), from which all the peripheral responses, such as anorexia, irritability, hyper-reactivity, lassitude, fatigue, and metabolic changes derive.
Term
what are the risk factors for any post-partum problems?
Definition
family hx, severe depression during pregnancy, past psych hx, sexual abuse hx, significant PMS, unplanned pregnancy, sleep deprivation, and no adequate social support.
Term
when are psych meds given to pregnant mothers?
Definition
when they pose a realistic threat to themselves/the baby - *except lithium which can cause epstein's heart anomaly (esp in the 1st trimester)*
Term
what are the options to treat a depressed nursing mother?
Definition
bottle feed and give meds or just give meds and let her continue nursing (antidepressants are more present in amniotic fluid than mother's milk)
Term
what are the categories of drug safety?
Definition
A: no risk. B: no controlled studies, but no sense drug is harmful. C: demonstrated ADRs in animal models, no evidence in humans. D: known human fetal risk, may be life-threatening. X: proven harmful to fetus, 100% contraindicated for pregnant women (such as valproic acid)
Term
why is menopause also called the "climacteric period"?
Definition
b/c it can also occur in men
Term
why is depression associated w/menopause?
Definition
the *loss* of emotions connected with reproductive cycle - combined with other changes associated w/aging (loss of friends/family). people who invest everything in family will be affected more by this.
Term
when is the incidence of major depression highest in women?
Definition
in the menopausal/climacteric period
Term
what symptoms are associated with menopause? tx?
Definition
symptoms: night sweats, sleep disturbance, vasomotor instability, loss of libido, vaginal dryness, and dyspareunia . tx: black cohosh/antidepressants/counseling.
Term
what is "instant menopause"?
Definition
hysterectomy - one must adjust psychologically to what made surgery necessary and to loss of body part and to loss of reproductive ability. (breast sx can have a similar effect).
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