Term
| equilibrium membrane potential |
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Definition
| the point where the electric field counteracts the force due to diffusion. determined by the nernst equation |
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Term
| chemically gated ion channel |
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Definition
| response from ligand being bound |
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Term
| voltage-gated ion channel |
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Definition
-response to change in voltage
-very selective |
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Term
| transmitter-gated ion channels are... |
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Definition
| insensitive to changes in voltage |
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Term
| voltage-gated sodium channels |
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Definition
-changes in voltage inc. chance that channel will be open
-open/closed/inactivated states
-takes long time to get out of inactive state |
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Term
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Definition
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Term
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Definition
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Term
| resting membrane potential (Vm) |
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Definition
-state where there is no net current across the cell
-all gated channels are closed
-value determined by ion conc. and permeability
-leak channels open
-na/k atpas maintains gradient |
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Term
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Definition
-more negative
-due to K leaving the cell or Cl entering |
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Term
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Definition
-more positive
-due to Na entering cell |
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Term
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Definition
| more negative, towards resting memembrane potential |
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Term
| excitatory postsynaptic potential (EPSP) |
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Definition
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Term
| inhibitory postsynaptic potential (IPSP) |
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Definition
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Term
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Definition
| 2 stimuli separated in time cause EPSPs that do not add together |
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Term
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Definition
| 2 excitatory stimuli close in time cause EPSPs that add together |
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Term
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Definition
| 2 simultaneous stimuli at different locations cause EPSPs that add together |
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Term
| spatial summation of EPSPs and IPSPs |
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Definition
| changes in membrane potential can cancel each other out |
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