Term
|
Definition
| irreversible COX-1 and COX-2 |
|
|
Term
|
Definition
|
|
Term
|
Definition
| prophylaxis of stroke and MI's |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Rheumatoid Arthritis, Propionic Acid |
|
|
Term
|
Definition
NSAID that can cause pseudoporphyria, 20X more potent than aspirin, longer half life
Propionic Acid |
|
|
Term
|
Definition
| patent ductus arteriosus CLOSURE |
|
|
Term
|
Definition
| Acetic Acid NSAID used for post surgery |
|
|
Term
|
Definition
|
|
Term
|
Definition
| long half life, potent modulator of neutrophils by inhibiting oxygen burst, |
|
|
Term
|
Definition
|
|
Term
|
Definition
| COX 2 and COX 3 inhibitor |
|
|
Term
|
Definition
| anti-pyretic (fever), mild to moderate pain reliever, not an anti-inflam or anti-platelet |
|
|
Term
|
Definition
| Hepatotoxicity, nephrotoxicity |
|
|
Term
|
Definition
| overdose is the leading cause of hepatic failure |
|
|
Term
|
Definition
| antidote for acetaminophen overdose |
|
|
Term
|
Definition
| selective inhibition of Cox -2 |
|
|
Term
|
Definition
| decreases efficacy of ACE inhibitors |
|
|
Term
|
Definition
Used for OA, RA, dysmenorrhea
Causes MI, GI bleeding
|
|
|
Term
|
Definition
| inhibit cox-2 action and prostaglandin biosynthesis by inducing lipcortins |
|
|
Term
|
Definition
inhibit ILA (cytokine antagonist)
only used for RA |
|
|
Term
| Etanercept, Infliximab, Adalimumab |
|
Definition
TNF-Alpha antagonist
RA and OA |
|
|
Term
|
Definition
| similar structure in all prostaglandins |
|
|
Term
|
Definition
| PGE1 analogue with vasodilator properties |
|
|
Term
|
Definition
maintence of patent ductus arteriosus
can cause DIC |
|
|
Term
|
Definition
Used for abortifacient
PGE1 analogue |
|
|
Term
|
Definition
| Cytoprotective and antisecretory effects against gastric ulcers in long-term NSAID therapy |
|
|
Term
|
Definition
|
|
Term
|
Definition
Abortion in second trimester
( cause contractions)
- can cause dystonia and pulmonary edema
|
|
|
Term
|
Definition
|
|
Term
| Latanoprost, Bimatoprost, Travoprost |
|
Definition
Ocular hypertension and Open angle glaucoma
can cause macular retinal edema |
|
|
Term
|
Definition
Prostacyclin analogue that stimulates vasodilation of the pulmonary and systemic arterial vasculature
tx: Pulmonary hypertension
|
|
|
Term
|
Definition
| inhibit thromboxane synthase |
|
|
Term
|
Definition
| thromboxane A2 receptor antagonist |
|
|
Term
|
Definition
| forms leukotrienes from Arachidonic acid |
|
|
Term
|
Definition
|
|
Term
|
Definition
used for asthma because causes bronchodilation
Side Effect: Increased liver function tests |
|
|
Term
|
Definition
| specific receptor for leukotriene receptor antagonists |
|
|
Term
|
Definition
| Leukotriene receptor antagonists |
|
|
