Term
| what is the chief precursor of eicosanoids |
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Definition
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Term
| what converts phospholipids to arachidonic acid |
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Definition
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Term
| what converts arachidonic acid to 5-HPETE |
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Definition
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|
Term
| what are the two types of 5-HPETE? |
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Definition
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Term
| what does the synthesis of leukotrienes require |
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Definition
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Term
| how is arachidonic acid converted to prostaglandins |
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Definition
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Term
| How is PGG2 converted to PGH2 |
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Definition
| peroxidase and reduced glutathione |
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Term
| how is PGH2 converted to thromboxanes |
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Definition
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Term
| arachidonic acid can be derived by what |
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Definition
| phospholipids and dietary linoleic acid |
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Term
| what is the function of prostacylins |
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Definition
| vasodilation, inhibition of platelet aggregation, increased cAMP |
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Term
| NSAIDS acts as blood thinners by blocking what? |
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Definition
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Term
| what is the main difference b/t Tylenol and Aspirin? |
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Definition
Tylenol has little to no anti-inflammatory effect
it inhibits COX-3 |
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Term
| what is the function of LTC4, LTD4, and LTE4? |
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Definition
contraction of smooth muscle
bronchoconstriction
vasoconstriction
increased vascular permeability
anaphylaxis |
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Term
| these products are the most important leukotrienes in humans. |
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Definition
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Term
| lipotoxins are synthesized by the combined action of |
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Definition
| 5-lipoxygenase and 15 lipoxygenase and synthesis can also occur via LT4 |
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Term
| what is inhibited by anti-inflammatory steroids? |
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Definition
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