Term
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Definition
By activating PPARα, there is enhanced elimination and decreased synthesis of VLDL (causing decreased TGs) and will increase HDL
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Term
| What can happe when reducing TGs? |
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Definition
When TGs are high, reducing TGs can increase LDL - be careful to monitor LDL when reducing TGs |
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Term
| Brand name for Fenofibrate? |
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Definition
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Term
| Does TriCor come in different strenghts? |
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Definition
Yes. And the delivery technology may be different. If you want to dispense a generic, may need to call prescriber for a cloes mg strength - and try to match one with a similar delivery technology, using the oragne book |
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Term
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Definition
Micronized formulations and other modes are used to improve bioavailability - to get a higher TG reduction (which are dose dependent) |
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Term
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Definition
| Statement. Not a question. |
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Term
When used in combination with statins, fenofibrates have less risk of myopathies (and rhabdomyolysis) than gemfibrozil. |
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Definition
| Statement. Not a question. |
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Term
| Fibrates should be taken once daily, with or without food, for all except? |
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Definition
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Term
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Definition
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Term
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Definition
| twice daily, 30 minutes before breakfast and dinner |
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