Term
| Anti-CD20 mAb used in non-Hodgkin's lymphoma and some leukemias |
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Definition
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Term
| Anti-Her2 used in breast cancer and gastric cancer |
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Definition
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Term
| mAb binds CD30 found on some lymphocytes including a number of lymphomas; conjugated to a cytotoxic drug (auristatin) |
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Definition
| Bretuximab vedotin (Adcetris) |
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Term
| Recombinant IL-2 (cytokine) conjugated to diphtheria toxin. IL-2 binds to CD25--> kills target cell. Used fro leukemias and lymphomas in which CD25 is expressed |
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Definition
| Denileukin Diftitox (Ontak) |
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Term
| mAb against CTLA4; used for malignant melanoma |
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Definition
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Term
| autologous cellular vaccine; used for prostate cancer |
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Definition
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Term
| alpha viral responses; seems to promote activation of T cells and acts on tumor cells to slow proliferation; severe side effects |
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Definition
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Term
| used for chronic myelogenous leukemia (CML) and other leukemias; Bcl-ABL+ |
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Definition
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Term
| small molecule TKI; inhibits TK portion of the intracellular region of EGFR |
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Definition
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Term
| binds and blocks GF itself, keeping ligand from being able to bind to the receptor and keep it from stimulating that pathway |
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Definition
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Term
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Definition
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Term
| used for multiple melanoma; constipates plasma cell, myeloma cells; block activation of NFKB |
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Definition
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Term
| used for multiple melanoma; constipates plasma cell, myeloma cells; block activation of NFKB |
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Definition
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