| Term 
 
        | Nonprescription Anti emetics |  | Definition 
 
        | Anti histamines, Bismuth subsalicylate, Emetrol |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: dimenhydrinate, meclizine hydrochloride 
 Action: inhibit vestibular stimulation in the middle ear
 
 Symptoms:anticholinergic (drowsiness, dry mouth, blurred vision caused by pupillary dilation, tachycardia (with anticholinergic use), urinary retention, and constipation
 
 These drugs should not be used by patients with glaucoma.
 |  | 
        |  | 
        
        | Term 
 
        | Bismuth subsalicylate (Pepto-Bismol) |  | Definition 
 
        | Action: acts directly on gastric mucosa to decrease irritation, also antibacterial |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Action: decreases n/v by changing the gastric pH, decreases smooth muscle contraction of the stomach 
 High sugar content, avoid with diabetes patients
 |  | 
        |  | 
        
        | Term 
 
        | Prescription Anti emetics |  | Definition 
 
        | Dopamine antagonists, Phenothiazines, Benzodiazepines, 5-HT3 receptor antagonists. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Butyrohenones: Droperidol, Haloperidol 
 Action:Block dopamine 2 receptors in the CTZ
 
 Side effects: EPS symptoms, hypotension
 
 May be used for post op nausea and vomiting.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: Promethazine 
 Also an antihistamine
 
 Side effects antihistamine and anticholinergic effects
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drug: lorazepam 
 action:Used for its antianxiety properties, used in combination with others for chemotherapy .
 |  | 
        |  | 
        
        | Term 
 
        | Nonprescription Anti emetics |  | Definition 
 
        | Anti histamines, Bismuth subsalicylate, Emetrol |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: dimenhydrinate, meclizine hydrochloride 
 Action: inhibit vestibular stimulation in the middle ear
 
 Symptoms:anticholinergic (drowsiness, dry mouth, blurred vision caused by pupillary dilation, tachycardia (with anticholinergic use), urinary retention, and constipation
 
 These drugs should not be used by patients with glaucoma.
 |  | 
        |  | 
        
        | Term 
 
        | Bismuth subsalicylate (Pepto-Bismol) |  | Definition 
 
        | Action: acts directly on gastric mucosa to decrease irritation, also antibacterial |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Action: decreases n/v by changing the gastric pH, decreases smooth muscle contraction of the stomach 
 High sugar content, avoid with diabetes patients
 |  | 
        |  | 
        
        | Term 
 
        | Prescription Anti emetics |  | Definition 
 
        | Dopamine antagonists, Phenothiazines, Benzodiazepines, 5-HT3 receptor antagonists. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Butyrohenones: Droperidol, Haloperidol 
 Action:Block dopamine 2 receptors in the CTZ
 
 Side effects: EPS symptoms, hypotension
 
 May be used for post op nausea and vomiting.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: Promethazine 
 Also an antihistamine
 
 Side effects antihistamine and anticholinergic effects
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drug: lorazepam 
 action:Used for its antianxiety properties, used in combination with others for chemotherapy .
 |  | 
        |  | 
        
        | Term 
 
        | 5-HT3 receptor antagonists |  | Definition 
 
        | Action: Blocks serotonin receptors in CTZ 
 Drugs: Ondanetron
 Increased efficacy with steroids; potentially fatal cardiac arrhythmia with IV route.
 
 Palonosetron:2nd gneration more potent, longer half life
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: dexamethasone, methylprednisolone 
 Use: cancer chemotherapy, given IV only for a short time
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: dronabinol, used when cannot take other antiemetics, avoid giving to patients with psychiatric disorders, can stimulate appetite for AIDS patients. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Metroclopramide- interacting with receptors for ach and dopamine on the gastrointestinal muscles and nerves, used to increase gastric emptying. Blackboxwarning- tardice dyskinesia.
 |  | 
        |  | 
        
        | Term 
 
        | Prescriptive antihistamines and anticholinergics |  | Definition 
 
        | Drugs: Hydroxyzine, Promethazine, Scolamine 
 Side effects: drowsiness, dry mouth, blurred vison caused by pupillary dialation, tachycardia(with anticholonergic use) and constipation
 
 Should not be used with patients with glaucoma.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drug: Ipecac 
 Action: stimulates the CTZ and acts directly on gastric mucosa
 
 Use Induces vomitting after toxic substance, onset of 15-30 minutes.
 
 Caution: avoid vomiting if substance is caustic or petroleum because can damage Esophagus on the way back up.
 Activated charcoal is given when emesis is contraindicated.
 |  | 
        |  | 
        
        | Term 
 
        | Antidiarrheal 3 categories |  | Definition 
 
        | Absorbents, Opioids, Somatastatin analogs. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs Bismuth-subsalicylate, Kaolin, Questran. 
 Action: coats GI tract, absorbs bacteria or toxins.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: Lomotil(sechedule 5 controlled substance), Loperamide(OTC) 
 Action: Rapid onset and effectiveness. At doses used for diarrhea, opioids do not produce dependence or serious adverse effects.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: octreotide Used for severe diarrhea from cancer
 Action: inhibits gastric acid, secretions, and hormones. Decreases smoothmuscle contractillity.
 |  | 
        |  | 
        
        | Term 
 
        | Nursing interventions for N/V |  | Definition 
 
        | *nonpharacological interventions *stay ahead of it, take it prophylactically
 *monitor vital signs, bowel sounds
 *monitor for dehydration
 *warn cilent to not take alcohol with antiemetics
 *Avoid giving to pregnant women
 *Avoid driving
 |  | 
        |  | 
        
        | Term 
 
        | Nursing interventions for anti diarrheals |  | Definition 
 
        | *Monitor BP and respirations *report more than 10 to 15 mm HG decrease in BP
 *Monitor bowel movements and sounds
 *Monitor electrolytes
 *If diarrhea persists after 48 hours, notify healthcare provider.
 |  | 
        |  | 
        
        | Term 
 
        | Treatment for constipation |  | Definition 
 
        | Laxatives- drugs that promote bowel movement Cathartic- drug thatpromotes strong and complete dowel emptying
 Purgatives- promotes watery stoll with cramping(harsh)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drug: Metamucil 
 *Absorbs water- add t the size of the fecal mass
 *Prevention and treatment of chronic constipation.
 *Slow onset of action
 *Not used when a rapid and complete bowel evacuation is necessary
 *administration: mix in glass of water or juice. stir and drink immediately followed by one glass of water.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: Colace, Amitiza(Cl channel activator) 
 *Cause more water and fat to be absorbed into the stools
 *emulsifies and lubricates the feces
 *used to prevent constipation
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: Ex-Lax, Dulcolax, Correctol 
 *Promote parastalsis by irritating the bowel
 *more likely to cause diarrhea and cramping
 *should only be used occasionally- may cause dependence and depletion of fluid and electrolytes
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drugs: Milk of magnesia, polyethlene glycol 
 *Cause water to be retained in the fecal mass to cause more watery stool
 *Used for surgical and diagnostic prep
 *Side effects: Fluid and electrolyte imbalances, hypotension, weakness
 |  | 
        |  | 
        
        | Term 
 
        | Contraindications of Laxatives |  | Definition 
 
        | *undiagnosed abdominal pain *inflammatory disorders of the GI tract: Appendicitis, diverticulitis, UC
 *Spastic colon
 *Bowel obstruction
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | *alternatives: high fiber diet, increased fluid *stool softeners and bulk products preferable to stimulants
 *laxative dependency
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | occurs when stomach contents backup through the LES into the esophagus |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Gastroesophageal Reflux Disease |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | *Ulcers in the stomach or intestine *single small round cavities; breakdown of mucosa
 *Caused by helicobacter pylori organism, some are due to medications few by stomach or intestinal cancers.
 |  | 
        |  | 
        
        | Term 
 
        | Drug treatment for Peptic ulcer disease |  | Definition 
 
        | *H2- receptor blockers *Antibiotics
 *Proton pump inhibitors
 *Antacids
 |  | 
        |  | 
        
        | Term 
 
        | Histamine-2 (H2) Receptor Antagonists |  | Definition 
 
        | Drugs: Zantac, Pepcid 
 *Prevents histamine from stimulating the H2 receptors on gastric parietal cells, reducing volume and concentration of gastric acid secretions.
 *Adverse effects are minor.
 *wait 30mins to an hour between taking antacid and H2 blocker
 *Zantac should not be taken with antacids, interacts with other meds and labs.
 |  | 
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