| Term 
 | Definition 
 
        | Low thyroid function "Hashimoto disease"
 Causes low TH levels and symptoms of slow metabolism
 Thyroid works harder and grows larger
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        | Term 
 | Definition 
 
        | Severe form of hypothyroidism in adults s/s include hair loss, firm & waxy skin, lethargy, seizures
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        | Term 
 | Definition 
 
        | Hypothyroidism in neonates Causes stunted physical growth and mental retardation
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        | Term 
 
        | Common signs and symptoms of hypothyroidism |  | Definition 
 
        | Thickened skin, decreased cardiac and respiratory rates (main concern), weight gain, loss of appetite, anorexia, muscle weakness, lethargy |  | 
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        | Term 
 
        | TH Replacement Drugs and their intended responses |  | Definition 
 
        | levothyroxine sodium (Synthroid, Levoxyl) liothyronine sodium (Cytomel, Triostat)
 Intended responses: Normal vital signs, maintain body weight, mental alertness, intact memory, normal bowel movement pattern
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        | Term 
 
        | Effects of TH Replacement Drugs on other medications |  | Definition 
 
        | -Enhance the action of Coumadin (increased bleeding) -Decrease levels of Lonoxen
 -Decrease effects of diabetic medication
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        | Term 
 
        | Side effects of TH Replacement Drugs |  | Definition 
 
        | Tachycardia, hypertension, warm skin, insomnia, increased bowel movements |  | 
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        | Term 
 
        | Adverse effects of TH Replacement Drugs |  | Definition 
 
        | Angina, heart attack, heart failure, seizures |  | 
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        | Term 
 
        | Patient teaching related to TH Replacement Drugs |  | Definition 
 
        | -Dosage is slowly increased over 2 to 3 weeks -Take exactly as prescribed
 -Take pulse at scheduled times: before taking drug and before bedtime
 -Do not take with a fiber supplement as it decreases the effects of the drug
 -If HR increases by 20 beats/min in 1 week contact physician
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        | Term 
 
        | Lifespan Considerations for TH Replacement Drugs |  | Definition 
 
        | Pediatric: Safe; medication adjusted with growth spurts Pregnancy and breastfeeding: Category A; may need higher doses; avoid breastfeeding
 Older Adults: More likely to experience adverse cardiac/nervous system effects
 Follow-up every 3 to 6 months
 Patients with diabetes may need higher doses of insulin; frequent blood glucose level checks
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        | Term 
 | Definition 
 
        | Overactive thyroid Caused by: Graves' disease, tumors, excessive thyroid growth, excessive iodine
 Also called: thyrotoxicosis (d/t affecting all organs)
 Faster metabolism
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        | Term 
 | Definition 
 
        | Cause of overactive thyroid Must have 3 components: Goiter, peritibal edema (swelling of lower legs but not pitting edema), exophalamos (bugging of eyes)
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        | Term 
 
        | Common signs and symptoms of hyperthyroidism |  | Definition 
 
        | -Skin hot and dry -Increased cardiac and respiratory rates
 -Weight loss/hair loss
 -Increased appetite (but loses weight)
 -Muscle weakness
 -Nervousness
 -Irritability
 -Unable to sleep well
 -Tremors
 -Altered menstrual flow
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        | Term 
 
        | Treatment of Hyperthyroidism |  | Definition 
 
        | Treatments destroys part/all of thyroid gland by: -Surgery (thyroidectomy)
 -radiation (need to stay home for 48 hours due to being radioactive
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        | Term 
 
        | Thyroid-suppressing drugs (for HYPERthyroidism)and their intended responses |  | Definition 
 
        | Drugs reduce hormone production prior to surgery -methimazole (Tapazole)
 -propylthiouracil (PTU)
 Intended response: Normal everything
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        | Term 
 
        | Sides effects of thyroid-suppressing drugs |  | Definition 
 
        | Rash, nausea, headache, muscle/joint aches |  | 
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        | Term 
 
        | Adverse effects of thyroid-suppressing drugs |  | Definition 
 
        | Bone marrow suppression (which leads to decreases RBCs which leads to anemia and increase risk for infection), hepatotoxicity, enhances activity of Coumadin |  | 
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        | Term 
 
        | What to check before and after administering thyroid-suppressing drugs |  | Definition 
 
        | Check before: Vital signs, liver function tests Check after: Blood counts; assess for jaundice (due to hepatotoxicity)
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        | Term 
 
        | Patient teaching related to thyroid-suppressing hormones |  | Definition 
 
        | -Medical follow-up -Regular monitoring of blood counts (INR)
 -Avoid crowds due to decreased immunity
 -Monitor for jaundice; report if present
 s/s of jaundice: yellow discoloration of white part of eyes and skin
 -Avoid food high in iodine
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        | Term 
 
        | Life Span Considerations for thyroid-suppressing drugs |  | Definition 
 
        | Pediatric: NOT USED UNDER AGE OF 6; use with caution on short-term basis Pregnancy & Breastfeeding: NOT USED Category D; causes miscarriages; avoid during breastfeeding
 Older adults: Severe adverse effects more likely
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        | Term 
 | Definition 
 
        | located behind the thyroid gland with one on each side; Parathyroid hormone (PTH) is secreted in response to a reduction in serum calcium levels |  | 
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        | Term 
 | Definition 
 
        | Need calcitriol to increase calcium absorption; vitamin D supplements may be given (assists in the absorption of calcium and bone resorption) |  | 
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        | Term 
 
        | Tips for patients with thyroid disorders |  | Definition 
 
        | -Too high of a dose will result in nervousness, irritability, and insomnia -Keep a log of pulse, weight, and mood status
 -For patients with hyperthyroidism: avoid foods high in iodine, such as soy, tofu, turnips, seafood, and iodized salt
 -Immediately report chest pain
 -Synthroid takes several weeks to months to reach a therapeutic level (lab tests every 6-12 months after therapeutic level)
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        | Term 
 | Definition 
 
        | transition time from normal periods to no periods for a full year |  | 
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        | Term 
 
        | Effects of high level of follicle stimulating hormone (FSH) |  | Definition 
 
        | -dilated blood vessels -hot flashes/night sweats
 -decreased mental concentration
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        | Term 
 
        | Effects of low estrogen levels |  | Definition 
 
        | -Cause unpleasant changes in skin, vaginal tissues -Increased rate of bone loss (osteoporosis)
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        | Term 
 
        | Hormone Replacement Therapy (HRT) and their intended responses |  | Definition 
 
        | -conjugated estrogens (Premarin) -methroxyPROGESTERone (Premphase, Prempro)
 
 Intended Response: Replace naturally secreted estrogen/progesterone with exogenous hormones during perimenopausal period
 -Reduce number, severity of hot flushes/night sweats
 -Reduce vaginal dryness
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        | Term 
 
        | Side effects of Hormone Replacement Therapy (HRT) |  | Definition 
 
        | breast tenderness, breakthrough bleeding, fluid-retention weight gain, acne |  | 
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        | Term 
 
        | Adverse effects of Hormone Replacement Therapy (HRT) |  | Definition 
 
        | increased blood clotting, hormone-sensitive cancers; liver impairment; gallbladder disease; pancreatitis |  | 
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        | Term 
 
        | Patient teaching related to Hormone Replacement Therapy (HRT) |  | Definition 
 
        | -take exactly as prescribed -annual screenings for breast, cervical, uterine, ovarian cancer
 -smoking cessation
 -monitor/report symptoms of jaundice
 -seek medical attention for: chest pain, difficulty breathing, swelling in one leg (blood clot), symptoms of a stroke
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