Term
| Pathophysiology and s/sx: Alzheimer's Disease |
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Definition
Pathophysiology: deficiency in AcH
S/Sx: formation of brain plaques, degredation of neuronal function |
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Term
| Drug Classes of AZD medications |
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Definition
Subclass: AcHase inhibitors
Drugs include:
Tacrine (Cognex)
Donezapil (Aricept)
Riastigme (Excelon)
Galantamine (Razadyne) |
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Term
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Definition
Generic: Tacrine
Class: AZD med
subclass: AcHase inhibitor
Note: popular but causes liver poblems; first drug developed |
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Term
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Definition
Generic: Donezepil
Class: AZD med
subclass: AcHase inhibitor
Note: popular but causes hepatotoxicity |
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Term
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Definition
Generic: Rivastigmine
Class: AZD med
subclass: AcHase inhibitor
Note: Permits more AcH in neurons, no evidence of hepatoxicity |
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Term
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Definition
Generic: Galantamine
Class: AZD med
subclass: AcHase inhibitor
Note: DOC, most effective |
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