Term
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Definition
| blocks reconversion of vitamin K |
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Term
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Definition
Binds to ATIII Activates it to bind to Xa & Thrombin Inactivates 13a, 11a, 9a |
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Term
Heparin LMWH Lovenox Fragmin Innohep |
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Definition
Mostly inhibits Xa, some antithrombin activity |
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Term
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Definition
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Term
Thrombin Inhibitors Lepirudin Angiomax |
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Definition
Binds to the catalytic site and substrate binding site of thrombin Best for patients with heparin-induced thrombocytopenia |
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Term
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Definition
| Only binds to catalytic site of thrombin |
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Term
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Definition
Inhibits cyclooxygenase and TXA2 production |
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Term
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Definition
Increases cAMP Decreases ADP and adenosine intake |
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Term
ADP Receptor Antagonists Ticlid Plavix |
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Definition
Prodrugs that bind to ADP receptor |
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Term
GPIIb-GPIIIa Inhibitors Abciximab Integrelin Aggrestat |
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Definition
Bind to receptor and inhibit it abciximab is the best |
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Term
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Definition
Binds to plasminogen, promotes fibrinolysis May cause hemorrhage and has major systemic effects |
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Term
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Definition
Binds to fibrin, promotes fibrinolysis Less systemic effects |
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Term
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Definition
Binds to fibrin, promotes fibrinolysis Less systemic effects |
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