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Drugs Affecting Adrenergic Function
prototypes and pharmacodynamics
9
Nursing
Undergraduate 2
02/06/2012

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Cards

Term

SNS receptor

Alpha 1

Definition
eyes, blood vessels, bladder, male sex organs, phorstatic capsule
Term

SNS receptor 

Alpha 2

Definition
presynaptic nerve terminals
Term

SNS receptors

Beta 1

Definition
primarily located in the heart, also in kidneys
Term

SNS receptors 

Beta 2

Definition

arterioles of heart, lungs, and skeletal muscle

bronchi, uterus, liver, skeletal muscle

Term
adrenergic agonists
Definition
  • drugs that mimic the action of SNS
  • classified according to selectivity
  • nonselective- stimulate both alpha & beta receptors
  • prototype: epinephrine
Term
epinephrine
Definition

nonselective adrenergic agonist

stimulates all adrenergic receptors and causes adverse effects in the cardiovascular system & CNS

Term
Alpha-1 Adrenergic Agonists
Definition

durgs that stimulate the alpha-1 receptor directly

prototype: phenylephrine (Allerest)

Term
Alpha-2 adrenergic agonists
Definition

stimulate alpha-2 receptors in teh CNS, decreases sympathetic outflow by inhibiting the release of norepinephrine

used primarily for HTN

Term
beta-adrenergic agonists
Definition

mimic the action of the SNS

labeled according to their selectivity

prototype: dopamine (Intropin)

stimulates alpha-1 & beta-1 receptors-increased cardiac output-increase BP, dilates renal a.

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