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Endocrine drugs
Pharm
36
Health Care
Undergraduate 1
05/24/2016

Additional Health Care Flashcards

 


 

Cards

Term
Exenatide
Definition
Exenatide (Byetta) is an incretin mimetic used for type 2 diabetes mellitus only. It is not recommended for clients taking insulin.
Term
methimazole (Tapazole
Definition

Treat hyperthyroidism

Administer methimazole with food.

Because of the increase in metabolism that occurs in hyperthyroidism, the client should consume a high calorie diet. Antithyroid medications can cause agranulocytosis with leukopenia and thrombocytopenia. Sore throat, fever, headache, or bleeding may indicate agranulocytosis and the health care provider (HCP) should be notified immediately.

Term
levothyroxine sodium (Synthroid)
Definition

Treat hypothyroidism

Insomnia, weight loss, and mild heat intolerance are side effects of levothyroxine sodium.

Term
Take levothyroxine (Synthroid) at what time
Definition
On a empty stomach
Term
propylthiouracil
Definition
Propylthiouracil (PTU) inhibits thyroid hormone synthesis and is used to treat hyperthyroidism, or Graves' disease.
Term
Glucagon
Definition

Glucagon is used to treat hypoglycemia resulting from insulin overdose. The family of the client is instructed in how to administer the medication. In an unconscious client, arousal usually occurs within 20 minutes of glucagon injection. When consciousness has been regained, oral carbohydrates should be given. Lipoatrophy and lipohypertrophy result from insulin injections.


Term
What change should happen if you give levothyroxine with warfarin?
Definition
Levothyroxine (Synthroid) accelerates the degradation of vitamin K–dependent clotting factors. As a result, the effects of warfarin (Coumadin) are enhanced. If thyroid hormone replacement therapy is instituted in a client who has been taking warfarin, the dosage of warfarin should be reduced.
Term

Humulin N insulin

onset, peak, and duration

Definition
onset of action is 1.5 hours, it peaks in 4 to 12 hours, and the duration of action is 16 to 24 hours. Hypoglycemic reactions most likely occur during peak time.
Term
Most common adverse effect of Metformin (Glucophage)
Definition

Biguanide- inhibit hepatic glucose production

The most common side effect of metformin (Glucophage) is gastrointestinal disturbances, including decreased appetite, nausea, and diarrhea.

Term
Desmopressin
Definition

Desmopressin is an antidiuretic hormone used in the treatment of diabetes insipidus. It promotes renal conservation of water by acting on the collecting ducts of the kidney to increase the permeability to water, which results in increased water reabsorption.

Term
When should lispro insulin be administered?
Definition
immediately before eating
Term
diabetic ketoacidosis
Definition

No Insulin to allow glucose into cell

Causes increase ketones which cause acidosis

Glucose concentration is raised past kidneys threshold to excrete it.

Which causes dehydration because of the high concentration of glucose causes osmotic diuresis effect

Leads to renal failure and total body depletion of potassium

Term
Sulfonylureas
Definition

Sulfonylureas promote insulin secretion by the pancreas and may also increase tissue response to insulin.


Term
Fludrocortisone acetate (Florinef) is prescribed for a client with Addison's disease. The nurse prepares to administer the medication. What is the primaryaction of this medication?
Definition

Fludrocortisone acetate has mineralocorticoid activity and also has a modest glucocorticoid effect. It acts primarily on the kidney distal tubules, enhancing the reabsorption of sodium and chloride ions and the excretion of potassium and hydrogen ions. It promotes water retention.


Term
The health care provider has prescribed Humulin R insulin 6 units and Humulin N insulin 20 units subcutaneously to be administered every morning. How should the nurse prepare to administer insulin?
Definition

Humulin R is always drawn up before Humulin N insulin, and Humulin N insulin can be drawn into the same syringe as for the Humulin R. Insulins usually are administered 15 to 30 minutes before a meal. To mix the Humulin N insulin suspension, the vial should be gently rotated. Shaking introduces air bubbles into the solution.


Term
While taking a potassium iodine solution(Lugol's solution) the client complains of a brassy metallic taste, how should the nurse respond?
Definition

withhold the medication and notify the HCP if these symptoms are noted.

The client should be instructed about symptoms of iodism that can occur with the administration of potassium iodide solution. These symptoms include a brassy taste, burning sensation in the mouth, and soreness of the gums and teeth.

Term
The nurse is providing instructions to a client with a diagnosis of Addison's disease regarding the administration of prescribed glucocorticoids. The nurse should provide which instruction to the client?
Definition

The client with Addison's disease will require lifelong replacement of adrenal hormones. The medications must be taken daily, and an alternate route of administration must be used if the client cannot take oral medications for any reason, such as nausea and vomiting. Additional doses of glucocorticoids will be needed during times of stress. The nurse must emphasize that the client must call the health care provider (HCP) to obtain a prescription for a dosage increase when experiencing stressful situations. Abrupt withdrawal of this medication can result in Addisonian crisis. Although side effects are mild at lower doses, more severe side effects occur with long-term glucocorticoid administration. It is very unsafe to stop taking the medication without first consulting the HCP.


Term

Humulin

onset, peak, and duration

Definition
Humulin N is an intermediate-acting insulin with an onset of action in 3 to 4 hours, a peak action in 6 to 12 hours, and a duration of action of 18 to 28 hours. A hypoglycemic reaction is most likely to occur at peak time.
Term
Tolbutamide
Definition

Tolbutamide is an oral hypoglycemic agent


Term
A client with aldosteronism is being treated with spironolactone (Aldactone). What is the MOA?
Definition

Potassium sparing diuretic

Spironolactone antagonizes the effect of aldosterone and decreases circulating volume by inhibiting tubular reabsorption of sodium and water. Thus, it produces a decrease in blood pressure. It increases the excretion of sodium and plasma potassium.

Term
Metformin
Definition
Metformin is an antidiabetic agent and acts by decreasing hepatic production of glucose. Metformin should be used with caution in clients with kidney or liver disease, heart failure, chronic lung disease, or a history of heavy alcohol consumption.
Term
A client is started on tolbutamide (Orinase) once daily. When should the nurse tell the client to take the medication?
Definition

Tolbutamide is an oral hypoglycemic agent that is taken in the morning with breakfast to minimize gastric irritation and enhance diabetic control. It stimulates the pancreas to produce the insulin that is needed during the day.


Term
A sulfonamide is prescribed for a client with a urinary tract infection. The client has diabetes mellitus and is receiving tolbutamide (Orinase). Because the client will be taking these two medications, which prescription should the nurse anticipate for this client?
Definition

Sulfonamides can intensify the effects of warfarin sodium (Coumadin), phenytoin (Dilantin), and orally administered hypoglycemics such as tolbutamide (Orinase). When combined with sulfonamides, these medications may require a reduction in dosage


Term
what is the normal adult maintenance dose range of levothyroxine (Synthroid).
Definition
The normal maintenance dosage range of levothyroxine in an adult is 0.1 to 0.2 mg daily.
Term
Nursing process of drawing up two different insulin in one syringe
Definition
Insulin dosages are verified by another nurse before administration. When two types of insulins are mixed, the doses must be verified after each is drawn up so as to verify the dosage for each one. The faster onset insulin is drawn up first.
Term
lipodystrophy
Definition
Tissue hypertrophy (lipodystrophy) involves thickening of the subcutaneous tissue at the injection sites. This dense tissue can interfere with the absorption of insulin, resulting in erratic blood glucose levels. Because the client has been on insulin for many years, this is the most likely cause of poor control.
Term
Glyburide (DiaBeta) daily is prescribed for a client. What instruction will the nurse include in the client's teaching plan?
Definition
Glyburide is a second-generation sulfonylurea used to treat diabetes mellitus. The client is instructed to take a single daily dose 15 to 30 minutes before breakfast. The medication is not used to prevent foot infections. Cholestatic jaundice is a potential adverse effect, and if the client exhibits signs of jaundice (skin color changes or pale stools), the HCP needs to be notified. Altered taste sensation is a frequent side effect and does not warrant HCP notification.
Term
The client with a head injury has begun excreting copious amounts of dilute urine through the Foley catheter. The client's urine output for the previous shift was 3000 mL. The nurse expects that the health care provider will prescribe which medication?
Definition

Desmopressin

A complication of head injury is diabetes insipidus, which can occur with insult to the hypothalamus, the antidiuretic hormone storage vesicles, or the posterior pituitary gland. Urine output that exceeds 9 L per day generally requires treatment with desmopressin. Dexamethasone is usually given to control cerebral edema secondary to brain tumors.

Term
Propylthiouracil (PTU)
Definition

Treat hyperthyrodism

adverse effect is agranulocytosis, which could be indicated by a fever

Term
A client who has been taking iodine solution (Lugol's solution, potassium iodide solution) is admitted to the emergency department, and an iodine overdose is suspected. Gastric lavage is initiated to remove the iodine from the stomach. In addition to treatment with gastric lavage, the nurse anticipates that which medication will be administered?
Definition

Sodium thiosulfate

Iodine solution can cause iodine toxicity. Iodine is corrosive, and an overdose will injure the gastrointestinal tract. Symptoms include abdominal pain, vomiting, and diarrhea. Swelling of the glottis may result in asphyxiation. Treatment consists of gastric lavage to remove iodine from the stomach and administration of sodium thiosulfate to reduce iodine to iodide

Term
acromegaly
Definition

A disorder in adults in which the pituitary gland produces too much growth hormone.


Term
Octreotide acetate (Sandostatin) is prescribed for a client with acromegaly. The nurse monitors the client, knowing that which side effect is associated with the administration of this medication?
Definition

Octreotide (Sandostatin) is used to reduce growth hormone levels in clients with acromegaly. The most common side effects of octreotide are diarrhea, nausea, gallstone formation, and abdominal discomfort.


Term
A hospitalized client with diabetes mellitus receives Humulin N insulin in the morning. The nurse monitors the client for hypoglycemia, knowing that the peak action is expected to occur how soon after the medication administration?
Definition

4 to 12 hours after administration


Term
Somatropin (Humatrope)
Definition

growth hormone

Somatotropin (Humatrope) should not be administered during or after epiphyseal closure. Efficacy of therapy declines as the client ages and is usually lost entirely by age 20 to 24 years.

Term
The nurse is caring for a client who is receiving growth hormone replacement therapy. The nurse monitors the client for what adverse effect of this therapy?
Definition
Hyperglycemia can occur as a result of the administration of growth hormone, particularly in a client with diabetes mellitus. Hypercalciuria can occur, particularly during the first 2 to 3 months of therapy. Growth hormone therapy is associated with a decline in thyroid function.
Term

The nurse is preparing to discharge a client who has had a parathyroidectomy. The discharge instructions include medication administration of oral calcium supplements that the client will need daily. When is the appropriate time to administer the supplement?


Definition

Oral calcium supplements can be administered with food to enhance its absorption as well as decrease gastrointestinal irritation.


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