Term
| used in Hodgkin's disease and non-Hodgkin's lymphomas |
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Definition
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Term
| most common nitrogen mustard, in many drug combinations (broad spectrum of activity) |
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Definition
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Term
| useful in the treatment of CNS tumors (lipophilic agents) |
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Definition
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Term
| common for treatment of testicular cancer; 1st line for ovarian cancer |
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Definition
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Term
| treatment of choriocarcinoma, a trophoblastic tumor was the first demonstration of curative chemotherapy; used in combo with other agents in ALL and carcinoma of the breast, cervix, lung, head, and neck |
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Definition
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Term
| exclusively used to treat solid tumors especially breast, colorectal and gastric tumors and squamous cell tumors of the head and neck |
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Definition
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Term
| narrow clinical spectrum and is primarily used in combo with daunorubicin or thioguanin for the txt of AML |
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Definition
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Term
| used primarily for the maintenance of remission in patients with ALL and is given in combo with MTX for this purpose |
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Definition
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Term
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Definition
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Term
| treatment of non-Hodgkin's lymphoma and chronic leukemia (CLL) |
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Definition
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Term
| one of the most effective against against solid tumors; also effective against acute leukemia and malignant leukemia |
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Definition
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Term
| most effective against lymphocytic and granulocytic leukemia; little activity against solid tumors |
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Definition
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Term
| effective as duanorubicin with less toxicity; also effective in some pts with advanced breast cancer |
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Definition
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Term
| used in combo therapy only! used in testicular cancer (with etoposide and Cisplatin), used in Hodgkin's Lymphomas (with Doxorubicin, Vinblastine, and Eecacarbazine |
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Definition
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Term
| Used with Doxorubicin, Bleomycin, and Decacarbazine for Hodgkin's Lymphomas |
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Definition
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Term
| Used with cyclophosphamide, hydroxydauoribiicin, and prednisolone for non-Hodgkin's lymphomas AND with mechlorethamine, procarbazine and prednisolone for Hodgkin's lymphomas; txt of solid tumors in children, tumors of the breast, cervix in adult. in combo with prednisolone for the induction of remission in childhood leukemia |
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Definition
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Term
| used in solid tumors: non-small cell lung cancer (NSCLC), ovarian and breast cancers |
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Definition
| Taxanes (Paclitaxel, Docetaxel) |
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Term
| second-line therapy for ovarian and small lung cancers |
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Definition
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Term
| first line therapy for metastatic colon cancer in combo with 5-FU and leucovorin; for metastatic pancreatic cancer in combo with 5-FU, leucovorin and oxaliplatin |
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Definition
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Term
| used in small cell lung cancer, germ cell tumors, and in combo with bleomycin for testicular cancer |
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Definition
| Epipodopyllotoxins (Etoposide or VP-16) |
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