Term
| all ADH hormone drugs promote |
|
Definition
|
|
Term
| all ADH hormone drugs can cause |
|
Definition
| water intoxication, inadequate tissue perfusion because of vasoconstriction |
|
|
Term
| use and action of desmopressin nasal spray, parenteral, oral preparations |
|
Definition
| treats DI, hemophilia, nocturnal diuresis, headache |
|
|
Term
| for all ADH hormone drugs, monitor for early signs of |
|
Definition
| water intoxication, drowsiness, listlessness, headache |
|
|
Term
| desmopressin nasal spray, parenteral, oral prep use and action |
|
Definition
| treats DI, hemophilia, nocturnal diuresis, headache |
|
|
Term
| desmopressin side effects |
|
Definition
| rhinorrhea, nasal irritation and congestion, dyspnea, hypertension, coronary vasoconstriction |
|
|
Term
| use and action of octreotide acetate, lanreotide |
|
Definition
| suppresses secretion of growth hormone, used to treat acromegaly |
|
|
Term
| side effects of octreotide acetate, lanreotide |
|
Definition
| n/v, diarrhea, headache, flushing, edema, dizziness, altered blood glucose, drowsiness, orthostatic hypotension, visual disturbances, cholelithiasis |
|
|
Term
| use and action fo bromocriptine |
|
Definition
| inhibits release of prolactin from anterior pituitary, suppresses lactation, restores ovulation, treats acromegaly, also used for parkinsons disease |
|
|
Term
| bromocriptine side effects |
|
Definition
| nausea, vomiting, constipation, hypotension, drowsiness, MI, pulmonary infiltrates, nasal stuffiness, vasoconstriction, anorexia, headache, visual disturbances, confusion |
|
|
Term
| dopamine agonist cabergoline use and action |
|
Definition
| prevent/inhibits secretion of prolactic, may lover GH secretion in some pts with acromegaly |
|
|
Term
| dopamine agonist cabergoline side effects |
|
Definition
| nausea, constipation, abdominal pain, headache, dizziness, asthenia, fatigue, drowsiness |
|
|
Term
| cabergoline is contraindicated with |
|
Definition
| uncontrolled hypertension |
|
|
Term
| pegvisomant use and action |
|
Definition
| used to treat acromegaly, prevents GH from exerting effects on body tissues |
|
|
Term
|
Definition
| infection, pain, injection site reaction, chest pain, back pain, flu syndrome, abnormal liver function tests, diarrhea, dizziness, edema, sinusitis |
|
|
Term
| pegvisomant is contraindicated with _____ because vial stopper contains ____ |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| hyponatremia in pts with normal blood volume, may be used for SIADH |
|
|
Term
|
Definition
| atrial fibrillation, nausea, vomiting, dry mouth, constipation, hematuria, anemia, dehydration, electrolyte imbalances, pain and redness at injection site |
|
|
Term
| vasopressin receptor antagonists |
|
Definition
|
|
Term
| fludrocortisone use and action |
|
Definition
| stimulates reabsorption of sodium and excretion of potassium and hydrogen ions in renal tubules, used to treat adrenal insufficiency |
|
|
Term
| fludrocortisone side effects |
|
Definition
| hypokalemia, nausea and vomiting, edema, hypertension, muscle, weakness, dizziness, tendon contractures |
|
|
Term
| glucocorticoid use and action |
|
Definition
| stimulate formation of glucose, promote storage of glucose as glycogen, affect fluid and electrolytes, increase hemoglobin, suppress inflammation, used to treat adrenal insufficiency, some also have mineralocorticoid effects |
|
|
Term
| glucocorticoids side effects |
|
Definition
| hypokalemia, hypocalcemia, n/v, edema, htn, increased risk of infection, hyperglycemia, muscle wasting, osteoporosis, ulcer development, acne, pathologic fractures, may cause death if suddenly discontinued |
|
|
Term
| give oral glucocorticoids with |
|
Definition
|
|
Term
|
Definition
| dexamethasone, prednisolone, flucinolone, fluorometholone, iotoprednol, medrysone, rimexolone |
|
|
Term
|
Definition
| suppresses adrenocortical function |
|
|
Term
|
Definition
| n/v diarrhea, lethargy, dizziness, hypouricemia, hearing and vision disturbances, BP changes, dyspnea |
|
|
Term
|
Definition
| ppl with polio and those who have recently had, DPT vaccine |
|
|
Term
| ketoconazole use and action |
|
Definition
| fungistatic, suppresses adrenocortical function |
|
|
Term
| ketoconazole side affects |
|
Definition
| nausea and vomiting, pruritus, diarrhea or constipation, GI bleeding, lethargy, headache, dizziness, adrenocortical insufficiency, thrombocytopenia, hemolytic anemia hepatotoxicity |
|
|
Term
| levothyroxine use and action |
|
Definition
| treat hypothyroidism and thyroiditis |
|
|
Term
| levothyroxine side effects |
|
Definition
| irritability, insomnia, nervousness, tachycardia, diarrhea, weight loss |
|
|
Term
| methimazole use and action |
|
Definition
| treat hyperthyroidism by interfering with the synthesis of thyroid hormones |
|
|
Term
|
Definition
| agranulocytosis, rash, thrombocytopenia, skin discoloration, fever, headache, drowsiness, diarrhea, nausea and vomiting |
|
|
Term
| saturated solution of potassium iodide use and action |
|
Definition
| reduces size and vascularity of the thyroid gland in hyperthyroidism, may be used before thyroidectomy |
|
|
Term
|
Definition
| excess iodine, fever, rase, oral lesions, metallic taste, diarrhea, parotitis, hypothyroidism |
|
|
Term
|
Definition
| dilute liquids in water, fruit juice or milk |
|
|
Term
| radioactive iodine use and action |
|
Definition
| used in thyroid scans, a higher therapeutic dose destroys thyroid tissue in hyperthyroidism and thyroid malignancies |
|
|
Term
| radioactive iodine side effects |
|
Definition
|
|
Term
|
Definition
| treatment of hypoparathyroidism, osteomalacia, prevention of vitamin D deficiency |
|
|
Term
|
Definition
| early toxicity, weakness, fatigue, GI disturbances, anorexia, constipation, severe hypercalcemia, polyuria, nocturia, proteinuria, seizures, confusion, ataxia, cardiac dysrhythmias |
|
|
Term
| calcium salts action and use |
|
Definition
| treatment of hypoparathyroidism along with vitamin d |
|
|
Term
| calcium salts side effects |
|
Definition
| high doses can cause hypercalcemia |
|
|
Term
|
Definition
| acetate, carbonat,e citrate, glubionate, gluconate, lactate, tricalcium, phosphate |
|
|
Term
| sulfonylureas use and action |
|
Definition
| stimulates pancreatic secretion of insulin |
|
|
Term
| sulfonylureas side effects |
|
Definition
| hypoglycemia, weight gain, sulfa allergy, hepatotoxicity, blood dyscrasias, photosensitivity, serious hypersensitivity |
|
|
Term
|
Definition
| glipizide, glyburide, glimepiride |
|
|
Term
| biguanides use and action |
|
Definition
| inhibits hepatic glucose production, increases insulin sensitivity, initial therapy for type 2 DM |
|
|
Term
|
Definition
| lactic acidosis, hypoglycemia when used with sulfonylurea or meglitinide |
|
|
Term
|
Definition
|
|
Term
| meglitinides use and action |
|
Definition
| stimulates pancreatic secretion of insulin |
|
|
Term
| meglitinides side effects |
|
Definition
| hypoglycemia, weight gain |
|
|
Term
|
Definition
|
|
Term
| pioglitazone use and action |
|
Definition
| increases insulin sensitivity in the tissues |
|
|
Term
| pioglitazone side effects |
|
Definition
| hypoglycemia when used with sulfonylurea or meglitinide, weight gain, decreased effectiveness of oral contraceptives, possible liver dysfunction, risk of heart failure and death in geriatric patients |
|
|
Term
| alpha-glucosidase inhibitors use and action |
|
Definition
| delays absorption of carbs in the intestine |
|
|
Term
| alpha glucosidase side effects |
|
Definition
| gi side effects, may cause hypoglycemia if taken with insulin or sulfonylureas, weakness, hunger, tremors, sweating, tachycardia |
|
|
Term
| alpha glucosidase inhibitors |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Dipeptidyl peptidase- 4 inhibitors use and action |
|
Definition
| increases insulin production and decreases hepatic glucose production |
|
|
Term
| Dipeptidyl peptidase- 4 inhibitors |
|
Definition
| sitagliptin, saxagliptin, alogliptin, linagliptin |
|
|
Term
| Dipeptidyl peptidase- 4 inhibitors side effects |
|
Definition
| occasional stomach upset and diarrhea, headache, peripheral edema, hypoglycemia, can cause pancreatitis, acute renal failure, anaphylaxis |
|
|
Term
|
Definition
|
|
Term
|
Definition
| hypoglycemia, blurred vision, dry mouth flushing, rash, urticaria, lipodystrophy, lipohypertrophy, peripheral edema |
|
|
Term
| pituitary hormone suppressants |
|
Definition
| octreotide acetate, lanreotide, bromocriptine, dopamine agonist, GH receptor antagonist, vasopressin receptor |
|
|
Term
|
Definition
|
|
Term
| adrenal glucocorticoid hormones |
|
Definition
| dexamethasone, prednisolone, fluocinolone, fluorometholone, loteprednol, medrysone, rimexolone |
|
|
Term
| adrenal mineralocorticoids |
|
Definition
|
|
Term
| adrenocortical cytotoxic agent |
|
Definition
|
|
Term
|
Definition
|
|
Term
| thyroid hormone replacement drug |
|
Definition
|
|
Term
|
Definition
|
|
Term
| drugs for hypoparathyroidism |
|
Definition
|
|
Term
| drugs for DM oral hypoglycemics |
|
Definition
| sulfonylureas, biguanides, meglitinides, thiazolidinediones, alpha glucosidase, Dipeptidyl peptidase- 4 inhibitors, sodium glucose |
|
|
