Term
Acetylcholine
class
mechanism
indications
effects
side fx |
|
Definition
class: cholinergic agonist
mech.: direct/non-selective agonst (muc/nic)
indications: miosis during eye procedures
effects: " "
side fx: gen. cholin. stim.
|
|
|
Term
bethanechol ("bethany-cole")
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergic agonist
mechanism: direct mus. agonst
indications: atonic/neurogenic bladder & ileus, some types of megacolon
effects: stim. intestinal motility/urination
side fx: gen. cholin. stim.
|
|
|
Term
carbachol (KAR-ba-kol)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergic agonist
mechanism: direct/non-selective agonist (mus/nic)
indications: reduce intraocular pressure during cataract surgery; chronic open angle glaucoma
effects: lower intraocular pressure
side fx: gen. cholin. stim.
|
|
|
Term
cevimeline (seh-VIM-eh-leen)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergic agonist
mech: direct mus. agonist
indications: sjogrens syndrome
effects: stim. gland secretion
side fx: gen. cholin. stim.
|
|
|
Term
pilocarpine (pye-loe-KAR-peen)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergic agonist
mech: direct mus. agonst
indications: emergency lower of intraocular pressure in primary glaucoma. sjorgens
effects: lower intraocular pressure; stim gland sec.
side fx: gen. cholin. stim.
|
|
|
Term
echothiophate ((ek-oh-THYE-oh-fate)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergic agonist
mech: indirect/AChE inhibitor (irrev)
indications: chronic open-angle glaucoma
effects: transient inc. in m. strength
side fx: gen. cholin. stim.
|
|
|
Term
Edrophium (ED roe FOE nee um)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergic agonist
mech: indirect/AChE inhibitor (reverse)
indications: myasthenia gravis, (dx & tx); reversal of NMJ blockade
effects: transient inc. in m. strength
side fx: gen. cholin. stim.
|
|
|
Term
neostigmine (neo-STIG-meen)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergic agonist
mech: indirect/AChE inhibitor (rever)
indications: atonic/neurogen bladder, megacolon; myasthenia gravis, reverse NMJ blockage
effects: stim. intestinal motility/urination, inc. m. strength
side fx: gen. cholin. stim.
|
|
|
Term
physostigmine (fi-zoe-STIG-meen)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergic agonist
mech: indirect/AChE inhibitor (revers)
indications: tx of CNS sx of anticholingergic OD
effects: stim peripheral and CNS cholinergic neurotransmission
side fx: Convulsions, gen. cholin. stim.
|
|
|
Term
atropine
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist
mech: mus. antagonist
indications: eye exam w/cycogplegia; cholingeric OD; GI hypermotility/incontinence
effects: mydriasis & cycloplegia; inhibits voiding/secretions
side fx: blind/dry/red/mad; latent gluacoma
|
|
|
Term
Ipratropium
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist
mech: mus. antagonist
indications: w/beta agonists (asthma); 1st line COPD
effects: bronchodilation
side fx: blind/dry
|
|
|
Term
scopolamine
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist
mech: muscar. antagonist
indications: motion sickness, surgery (amnestic, sedative)
effects: amnestic, sedative
side fx:blind/dry/hot/mad
|
|
|
Term
mecamylamine (mek-ah-MIL-a-meen)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist
mech: non-depol nicotinic (ganglia) antagonist
indications: mod to severe htn, not 1st line
effects: dec BO by blocking sym output to CV system
side fx: many
|
|
|
Term
trimethaphan
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist
mech: non-depol nicotinic (ganglia) antagonist
indications: htn emergency; controlled hypotension in surgery
effects: dec BP by blocking CV system
side fx: many
|
|
|
Term
nicotine
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric agonist/antagonist
mech: depol nicotinic antagonist (ganglia/NMJ/CNS)
indications: smoking cessation
effects: dose dependent central and peripheral fx
side fx:
|
|
|
Term
cisatracurium (sis-ah-trah-KYOO-ree-um)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist NM blocker
mech: non-depol nicotinic (NMJ) blocker; spontaneous degradation
indications: m. relax in surgery
effects: NM blockade
side fx:
|
|
|
Term
rapacuronium
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist NM blocker
mech: non-depol nicotinic (NMJ) blocker; liver metabolism
indications: m. relax during surgery
effects: NM blockage
side fx: caution in pts w/liver disease
|
|
|
Term
succinylcholine
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist NM blocker
mech: depolarizing nicotinic antagonist; esterase metab
indications: ET tube
effects: NM blockage
side fx: many: ganglionic stim, mus agonist, hyperkalemia; malignant
|
|
|
Term
tubocurarine (tū′bō-kyū-ra′rin)
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist NM blocker
mech: non-depol nicotonic (NMJ and ganglia) antagonist; excreted
indications: m. relax in surgery
effects: NM blockage
side fx: ganglionic block (hypotension and reflex tachycardia)
|
|
|
Term
botulinum toxin
class
mechanism
indications
effects
side fx
|
|
Definition
class: cholinergeric antagonist
mech: blocks ACh by cleaving vesicle ptns
indications: excessive sweating, cervical dystonia, strabismus, blepharospams, HA, spastic disorders, cosmo
effects: denervation of m.
side fx: many, ptosis
|
|
|
Term
dobutamine (doe-BYOO-ta-mean)
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (catecholamine)
mech: b-1 > b-2 >a-1 agonist
indications: CHF; chemical stress test
effects: inotrophic agent w/little effect on heart rate
side fx: arryhthmias; angina; MI
|
|
|
Term
dopamine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (catecholamine)
mech: D1-5 receptor agonist; beta > alpha
indications: shock
effects: inc. kidney perfusion (vasodil of mesentaric and renal vascular beds); cardiac stim.
side fx:
|
|
|
Term
epinephrine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (catecholamine)
mech: alpha and beta agonist
indications: cardiac life support; asthma, open-angle glaucoma, anaphylaxis, local anesthesia
effects: cardiac stimulant, bronchodil, vasoconstriction
side fx: arrthmias, MI, CNS (anxiety, fear), htn HA, pulmonary edema, cerebral hemorrhage
|
|
|
Term
isoproterenol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (catecholamine)
mech: beta-1 and 2 agonist
indications: emer. cardiac stim, occasional for asthma
effects: cardiac stim, reduced PVR, bronchiodil
side fx: arrythmias, angina, MI, CNS (fear/anxiety)
|
|
|
Term
norepinephrine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (catecholamine)
mech: alpha > beta agonist
indications: pressor, shock
effects: inc. PVR/reflex bradycardia, asthma/COPD, anaphylaxis, prolong local anesthetics
side fx: kidney failure during shock
|
|
|
Term
albuterol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (non-catecholamine)
mech: beta-2 agonist
indications: asthma, COPD
effects: brochodil
side fx: CNS (anxiety, fear, tension, HA, tremor)
|
|
|
Term
clonidine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (non-catecholamine)
mech: alpha-2 agonist
indications: htn, many others
effects: dec BP via CNS, many other
side fx: bradycardia, many other
|
|
|
Term
methoxamine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (non-catecholamine)
mech: alpha-1 agonist
indications: reverse hypotension during anesthesia; evoke brady during tachycardia
effects: inc PVR, reflex bradycardia
side fx: htn HA, N/V, pulmonary edema, cerebral hemorrhage
|
|
|
Term
phenylephrine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (non-catecholamine)
mech: A-1 > A-2 agonist
indications: mydriasis (eye exam); decogestant; evoke reflex bradycardia during tachy
effects: inc PVR/reflex bradycardia, decongestant; mydriasis
side fx: htn HA
|
|
|
Term
salmeterol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (non-catecholamine)
mech: long lasting beta-2 agonist
indications: asthma, COPD
effects: bronchodil
side fx: CNS fx (fear, anxeity, tremor, HA...)
|
|
|
Term
terbutaline
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (non-catecholamine)
mech: B-2 agonist
indications: asthma/COPD, reduce/delay premature contractions
effects: bronchodil, relaxation of smooth m.
side fx: CNS (fear, tremor, tension, HA, anxiety)
|
|
|
Term
ephedrine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (non-catecholamine)
mech: mixed, action-potential independent NE release, direct: A and B agonist
indications: nasal congestion; asthma; inc BP; performance enhancer
effects: decogest, bronchodil; cardiac stim; inc BP and metab; mild CNS stim
side fx: death, FDA prohibited in supplements
|
|
|
Term
amphetamine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic agonist (non-catecholamine) psychostimulant
mech: indirect: action-potential independent NE release
indications: AHDH, narcolepsy
effects: strong CNS (elation, alertness, inc. self-conf, loss apetite)
side fx: addiction, dependent, withdrawm
|
|
|
Term
tyramine
class
mechanism
indications
effects
side fx
|
|
Definition
class: tyrosine metabolism, byproduct in wine/cheese
mech: indirect: AP indep NE release
indications:
effects: in presense of MAOI, dangerous inc. in BP, fever, swelling, sweating, HAs
side fx: food-drug interaction w/MAOIs
|
|
|
Term
cocaine
class
mechanism
indications
effects
side fx
|
|
Definition
class: psychostimulant
mech: indirect: inhibition of MO uptake
indications:
effects: amphetamine-like fx
side fx: addiction, dependence withdrawl
|
|
|
Term
phenoaxybenamine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adernergic antagonist
mech:irrev. alpha adrenergic (non-selective)
indications: pheochromocytoma; raynauds disease
effects: dev PVR, reflex inc. of cardiac output, delayed onset/biotransformation, long duration)
effects:
side fx: orthostatic htn, nasal congestion, miosis, tachycardia/angina
|
|
|
Term
phentolamine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: rev. alpha antagonist
indications: pheochromocytoma; reversal of vasoconstriction after accident infusion of alpha agonist
effects: dec. PVR, reflex inc. cardiac output
side fx: orthostatic hypotension, nasal congestion, miosis; tachycardia/angina
|
|
|
Term
doxazosin
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: alpha-1 antagonist
indications: htn, BPH, raynauds disease
effects: dec PVR
side fx: orthostatic hypotension, dizziness/vertigo, tachycardia, hypotension
|
|
|
Term
prazosin
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: alpha-1 antagonist
indications: htn, raynauds disease
effects: dec PVR
side fx:orthostatic htn, dizziness/vertigo, tachycardia, hypotension
|
|
|
Term
terazosin
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: alpha-1 antagonist
indications: htn, BPH, raynaud disease
effects: dec PVR
side fx: orthostatic hypotension, dizziness/vertigo, tachycardia
|
|
|
Term
atenolol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: beta-1 antagonist
indications: htn for ptns w/asthma, COPD, DM, bradycardia; angina
effects: dec CO, oxygen demand and BP, little fx on PVR
side fx: cardiac failure, bradycardia; hypotension/fatigue
|
|
|
Term
esmolol (ES-moe-lol)
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: beta-1 antagonist
indications: short acting parenteral antagonist for arrhythmia and htn
effects: dec CO, oxygen demand, BP; little fx on PVR, pulmonary, metabolism
side fx: cardiac failure, bradycardia/arrhythmia
|
|
|
Term
metoprolol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: beta-1 antagonist
indications: htn for pts w/asthma, COPD, DM, bradycardia; angina, post-MI
effects: dec CO, oxygen demand, BP; little fx on PVR, pulmonary, metabolism:
side fx: cardiac failure, bradycardia, hypotension/fatigue
|
|
|
Term
propranolol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: beta-1, beta-2 antagonist
indications: htn, migraine, hyperthyroidism; angina; post-MI, arrhythmias, performance anxiety
effects: dec CO, O2 demand, and BP; brochoconstriction, metabolic fx
side fx: cardiac failure, arrhythmias, bronchoconstriction, hypotension, fatigue
|
|
|
Term
timolol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: beta-1 & beta-2 antagonist
indications: htn, open-angle glaucoma, post MI
effects: dec CO, O2 demand, BP, bronchoconstriction, dec. intraoccular pressure
side fx: visual disturbances, cardiac failure, arrhythmias, brochoconstriction, hypotension/fatigue
|
|
|
Term
nadolol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: long lasting B1 and B2 antagonist
indications: htn, angina
effects: dec CO, O2 demand, and BP; bronchoconstriction
side fx: cardiac failure, arrhythmias, bronchoconstriction, hypotension/fatigue, hypoglycemia in IDD
|
|
|
Term
acebutolol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: B1 antagonist w/ISA
indications: htn for select pts (asthma, COPD, DM, bradycardia)
effects: mild dec in CO, O2 demand and BP; little fx on PVR, pulmonary, metab
side fx: cardiac failure, bradycardia; hypoten/fatigue
|
|
|
Term
pindolol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: B1 and B2 antagonist w/ISA
indications: htn (asthma, COPD, DM, bradycardia)
effects: mild dec in CO, O2 demand, BP; bronchoconstriction
side fx: cardiac failure, bradycardia; hypoten/fatigue
|
|
|
Term
labetalol
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: A1 and B2 antagonist
indications: pheochromocytoma; htn emergencies
effects: dec PVR, dec CO
side fx: orthostatic htn, cardiac failure, bradycardia; hypotension/fat
|
|
|
Term
reserpine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: indirect: blocks NE, DOPA, 5-HT reuptake
indications: rarely used, mild htn
effects: gradual reduction in BP and CO
side fx: many: N, gastric intolerance, weight gain, etc
|
|
|
Term
guanethidine
class
mechanism
indications
effects
side fx
|
|
Definition
class: adrenergic antagonist
mech: indirect: blocks AP dependent release of NE
indications: rarely used, mild htn
effects: gradual reduction in BP and CO
side fx: many N, ...weight gain, etc
|
|
|
Term
prostaglandin E1
class
mechanism
indications
effects
side fx
|
|
Definition
PGE1
class: Endogenous eicosanoid
mech: cell type dependent, agonist at all subtypes of EP Rs
indications: ED, maintain patent ductus arteriosus
effects: vasodilation, inhibits platelet aggreg
side fx: apnea, bradycardia, hypotension, hyperpyrexia
|
|
|
Term
prostaglandin E2
class
mechanism
indications
effects
side fx
|
|
Definition
class: Endogenous eicosanoid
mech: cell type dependent; agonist at subtypes of EP Rs
indications: facilitate labor & induce abortion
effects: better PG-F inducing labor; inhibits ADH; natriuresis; vasodilation
side fx: fever, GI: cramps, diarrhea
|
|
|
Term
prostaglandin I2
class
mechanism
indications
effects
side fx
|
|
Definition
class: Endogenous eicosanoid
mech: agonist at IP Rs; activation of adenylyl cyclase
indications: primary pulmonary htn, heparin substitute for platelet harvesting
effects: vasodilation, inhibits platement aggreg.
side fx: flushing, HA, hypotension, nausea, diarrhea
|
|
|
Term
prostaglandin F2a
class
mechanism
indications
effects
side fx
|
|
Definition
class: Endogenous eicosanoid
mech: agonist at FP Rs, activation of phospholipase C
indications: facilitates labor, induces abortion
effects: non-vascular smooth m. contraction, vasoconstriction
side fx: bronchoconstriction, pulmonary htn, NVD
|
|
|
Term
carboprost
class
mechanism
indications
effects
side fx
|
|
Definition
class: synthetic PGF analog
mech: mimics PGF2 alpha, longer duration
indications: postpartum hemorrhage, induces abortion
effects: oxytocic, smooth m. contraction
side fx: vomiting, diarrhea, bronchoconstriction
|
|
|
Term
thromboxane A2
class
mechanism
indications
effects
side fx
|
|
Definition
class: Endogenous eicosanoid
mech: agonist at TP Rs; increased Ca++ influence on target cell
indications: none
effects: vasoconstriction, brochoconstriction, platelet aggregation...
side fx:
|
|
|
Term
leukotriene B (LTB4)
class
mechanism
indications
effects
side fx
|
|
Definition
class: Endogenous eicosanoid
mech: agonist at LT R (BLT); activation of phospholipase C
indications: none
effects: chemotaxis/recruitment of inflammatory cells
side fx:
|
|
|
Term
cysteinyl leukotrienes (LTs C, D, E)
class
mechanism
indications
effects
side fx
|
|
Definition
class: Endogenous eicosanoid
mech: agonists at LT R (cysLT subtypes); activation of PLC
indications: none
effects: vasoconstriction; inc. capillary permeability
side fx:
|
|
|
Term
iloprost
class
mechanism
indications
effects
side fx
|
|
Definition
class: syn. protaglandin mimic
mech: mimics PGI
indications: primary pulmonary htn, via inhalation
effects: see PGI
side fx: see PGI, also cough
|
|
|
Term
misoprostol
class
mechanism
indications
effects
side fx
|
|
Definition
class: synthetic prostaglandin
mech: mimics PGE2
indications: prevent ulcers by NSAIDs, induce abortion
effects: gastric cyoprotection, oxytocic
side fx: see PGE
|
|
|
Term
latanoprost
class
mechanism
indications
effects
side fx
|
|
Definition
class: synthetic prostaglandin
mech: analogue of and mimics PGF2 alpha
indications: ocular htn; glaucoma
effects: topical, reduces intraocular pressure
side fx: pigmentation of iris, eyelids; inflammation/irritation; eyelash growth
|
|
|
Term
bimatoprost
class
mechanism
indications
effects
side fx
|
|
Definition
class: syt. prostaglandin mimic
mech: prostandin analogue that mimics PGF2 alpha
indications: ocular htn; glaucoma
effects: topical, reduces intraocular pressure
side fx: pigmentation of iris, eyelids; irritation/inflammation; eyelash growth
|
|
|
Term
NSAIDs
class
mechanism
indications
effects
side fx
|
|
Definition
mech: inhibit COX 1 & 2
indications: inflammation, pain, fever
effects: dec inflammation, dec pain/fever, dec risk of colorectal ca
side fx:ulcers, weight gain (fluid retent), a. htn, inc thromotic events, unselective agents cause inc. bleeding time due to inhibition of plt TXA formation
|
|
|
Term
aspirin
class
mechanism
indications
effects
side fx
|
|
Definition
class: PG syn inhib, a tNSAID w/some COX1 at low [ ]
mech: COX1/2 inhibitor
indications: MI prophylaxis, risk for thrombosis, inflammation
effects: dec. pain/inflammation
side fx: reyes syndrome, see NSAIDs
|
|
|
Term
ibupropen
class
mechanism
indications
effects
side fx
|
|
Definition
class: PG synthesis inhibitor, tNSAID
mech: COX1/2 inhibt
indications: inflam, pain, fvr
effects: see NSAIDs
side fx: see NSAIDs
|
|
|
Term
celecoxib
class
mechanism
indications
effects
side fx
|
|
Definition
class: PG syn inhibib, "Coxib"
mech: COX1/2
indications: inflam, pain, fvr
effects: dec pain/inflam
side fx: see NSAIDs, allergy in pts w/sulfonamide allergy
|
|
|
Term
acetaminophen
class
mechanism
indications
effects
side fx
|
|
Definition
class: weak PG inhib, not anti-inflammatory
mech:
indications: pain, fvr
effects: dec. pain/fvr
side fx: liver toxicity w/alcohol
|
|
|
Term
glucorticoids
class
mechanism
indications
effects
side fx
|
|
Definition
class: steroid anti-inflam
mech: inhib COX2 directly, inhib phospholipase indirectly
indications: asthma, inflammation
effects: many
side fx: many
|
|
|
Term
zileuton
class
mechanism
indications
effects
side fx
|
|
Definition
class: leukotriene syn inhib
mech: inhibits 5-lipoxygenase
indications: asthma prophylaxis
effects: bronchoconstriction
side fx: liver toxicity
|
|
|
Term
zafirlukast
class
mechanism
indications
effects
side fx
|
|
Definition
class: leukotriene antagonist
mech: blocks CYSLT1 R
indications: asthma prophylaxis
effects: dec. bronchoconstriction
side fx: eosinophilic vasculitis (Churt-strauss syndrome)
|
|
|
Term
montelukast
class
mechanism
indications
effects
side fx
|
|
Definition
class: leukotriene antagonist
mech: blocks CYSLT1 R
indications: asthma prophylaxis
effects: dec. bronchoconstriction
side fx: eosinophilic vasculitis (Churt-strauss syndrome)
|
|
|
Term
propranolol
mechanism
indications
effects
side fx
|
|
Definition
mech: comp ns B adr R antag
indications: chronic htn; sym stim of hyperthy, dec angina, post MI, afib,
effects: antag B adr R dec force and rate, a1 not blocked thus PVR inc; red sys and dias and inc Na retention
side fx: coldness in extremities, arrhyt, bronchoconst, hypoglycemia, inc B1 R expression
|
|
|
Term
nadolol
mechanism
indications
effects
side fx
|
|
Definition
mech: comp ns B adr R antag
indications: chronic htn; sym stim of hyperthy, dec angina, post MI, afib
effects: antag B adr R dec force and rate, a1 not blocked thus PVR inc; red sys and dias and inc Na retention…once daily dosing
side fx: coldness in extremities, arrhyt, bronchoconst, hypoglycemia, inc B1 R expression
|
|
|
Term
timolol
class
mechanism
indications
effects
side fx
|
|
Definition
mech: comp ns B adr R antag
indications: inc IOP w/open angle glaucoma
effects: inhib of B adr R in aqueous humor secretion in ciliary body
side fx: visual disturbances (limited due to no local anesthetic)
|
|
|
Term
antenolol
class
mechanism
indications
effects
side fx
|
|
Definition
mech: comp B1 adr R antag
indications: htn, angina
effects: no insulin induced hypoglycemia
side fx: cardiac failure, brady/arrhy, hypotension/fatigue
|
|
|
Term
metoprolol
class
mechanism
indications
effects
side fx
|
|
Definition
mech: comp B1 adr R antag
indications: htn, angina, s/p MI
effects: antag B adr R dec force and rate, a1 not blocked thus PVR inc; red sys and dias and inc Na retention, no insulin induced hypoglycemia…P450 2D6
side fx: cardiac failure, brady/arrhy, hypotension/fatigue
|
|
|
