Term
| Drugs that may chelate with Mg, Ca, etc |
|
Definition
| tetracyclines, macrolides, quinolones, bisphosphonates |
|
|
Term
| Drugs that alter pH of the gut |
|
Definition
| H2 antagonists, PPIs, antacids, vitamin c |
|
|
Term
| Antibiotics altering GI flora affects: |
|
Definition
| warfarin, oral contraceptives, digoxin levels |
|
|
Term
| Drugs that INHIBIT p-glycoprotein (3A4 drugs) |
|
Definition
| amiodarone, atorvastatin, clarithromycin, cyclosporine, diltiazem, verapamil, propranolol |
|
|
Term
| drugs that INDUCE p-glycoprotein (3A4 drugs) |
|
Definition
| Rifampin, St. John's Wort, Yohimbine, ritonavir |
|
|
Term
| Drugs Affecting Protein Binding (>90% bound) |
|
Definition
| aspirin, Coumadin, phenytoin |
|
|
Term
|
Definition
| oral anticoagulants, quinidine, corticosteroids, theophylline, nevirapine, chronic ethanol, rifampin, carbamazepine, isoniazid, St. John's Wort |
|
|
Term
|
Definition
| xanthenes, warfarin, clozapine, amiodarone, quinolones, ticlopipine |
|
|
Term
|
Definition
|
|
Term
|
Definition
| diazepam, omeprazole, cimetidine, fluoxetine, ketoconazole, ticlopipine, topiramate |
|
|
Term
|
Definition
| amiodarone, fluconazole, paroxetine |
|
|
Term
|
Definition
| amiodarone, cimetidine, fluoxetine, paroxetine, ritonavir, haloperidol, nortriptyline, venlafaxine, risperidone |
|
|
Term
|
Definition
|
|
Term
|
Definition
| erythromycin, terfenadine, carbamazepine, lidocaine, quinidine, sevral corticosteroids, cyclosporine, protease inhibitors, amiodarone, cimetidine, diltiazem, azole antifungals, grapefruit juice, verapamil |
|
|
Term
| Inhibits excretion of penicillin (good); inhibits excretion of methotrexate (bad) |
|
Definition
|
|
Term
| drugs that inhibit renal PGP (can increase digoxin) |
|
Definition
| amiodarone, cimetidine, quinidine |
|
|
Term
| drugs that can affect lithium levels by altering sodium reabsorption |
|
Definition
| NSAIDs, diruetics (HCTZ, furosemide) |
|
|
Term
|
Definition
| garlic, ginko, ginseng, green tea, ginger |
|
|
Term
| narrow therapeutic window medications |
|
Definition
| digoxin, phenytoin, carbamazepine, aminoglycosides, warfarin, lithium, cyclosporine, theophylline |
|
|
Term
|
Definition
| Phenytoin, Smoking, Phenobarbital, Oxcarbazepine, Rifamycins, Carbamazepine, St. John's Wort |
|
|
Term
|
Definition
| Grapefruit, Protease Inhibitors, Azole ANtifungals, Cimedtidine, Macrolides, Amiodarone (+ dronedrarone), Non-DHP calcium channel blockers |
|
|
Term
|
Definition
| Alcohol, Levothyroxine, Fluconazole, Amiodarone, Metronidazole, Erythromycin, Sulfa |
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