Term
|
Definition
| greater cns entry compared to morphine |
|
|
Term
|
Definition
addiction rehab
no high
plateau of action |
|
|
Term
|
Definition
substitution drug
mu agonist
kappa antagonist |
|
|
Term
d2-adrenergic agonist
(clonidine) |
|
Definition
| reduces withdrawal symptoms by reducing sympathetic outflow |
|
|
Term
|
Definition
|
|
Term
gamma hydroxybutyrate
GHB |
|
Definition
date rape drug
GABA analog
rapid hypnotic anterograde amnesia |
|
|
Term
|
Definition
stimulant
inhibits dopamine and NE reuptake
snorted as a hydrochloride salt or free base (crack) for better cns entry
overdose = hypertensive crisis
Use= anesthetic |
|
|
Term
|
Definition
release catecholamines into synaptic cleft
easy to synthesize from pseudoephedrine
can smoke crystals (crank) |
|
|
Term
|
Definition
release catacholamines into synaptic cleft
more serotonin (hallucinogenic) effects than stimulant |
|
|
Term
|
Definition
mech: nicotine receptor partial agonist
use: smoking cessation
adv: suicide! |
|
|
Term
|
Definition
| do not effect dopaminergic pathway so not physiologically addicting |
|
|
Term
|
Definition
signs of intox:
increased pulse rate
reddening of conjuctiva |
|
|
Term
|
Definition
| EtOH converted into acetaldehyde by alcohol dehydrogenase. acetaldehyde converted to acetate by aldehyde dehydrogenase |
|
|
Term
|
Definition
inhibits aldehyde dehydrogenase
use: AA |
|
|
Term
|
Definition
GABA agonists increase EtOH effects
GABA antagonists decrease EtOH effects |
|
|
