Term
| Name the 3 types of dose-response relationships. |
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Definition
1. Sigmoid (AKA nonlinear)
2. Direct-Linear
3. Linear Quadratic |
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Term
| For which type of dose-response relationship is there a threshold dose? |
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Definition
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Term
| All nonstochastic effects have which type of dose-response relationship? |
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Definition
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Term
| Erythema and cataracts have which type of dose-response relationship? |
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Definition
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Term
| Why do all 3 types of dose-response relationship graphs for any type of effect start slightly above zero? |
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Definition
| Because the endemic (naturally-occuring) level is the starting point - in other words, in a given group even with no dose (0 on dose axis), there will still be people with that effect who are part of the naturally-occurring percentage. |
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Term
| Of the 3 types of DRR, which is the worst type and why? |
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Definition
| Direct-Linear relationship, because there is no safe threshold - any radiation at all increases the chance of the effect and it is linear - as the dose goes up, the chance goes up directly (it goes up less steeply with Linear-Quadratic) |
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Term
| Of the three types of DRR, which is the best type and why? |
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Definition
| Sigmoid (or nonlinear), because there is a safe threshold - at low levels, the effect doesn't show up. The other two have no safe threshold, although L-Q is a little safer than L-D. |
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Term
| What shape does the sigmoid DRR graph have? |
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Definition
| An "S" - stays at 0 for low doses (the bottom of the "S", then slants up after the threshold is reached until it hits the dose where 100% show the effect, then goes horizontal again (the top of the "S) |
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Term
| Stochastic effects all have *** or *** DRRs? |
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Definition
| Linear-Direct or Linear-Quadratic |
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Term
| The effect of genetic mutations in reproductive cells has what type of DRR? |
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Definition
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Term
| When an effect has a Linear-Quadratic DRR, at low doses the effect has a/an *** relationship with dose, while at high doses, it has a/an *** relationship with dose. (linear/exponential) |
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Definition
At low doses, linear.
At high doses, exponential. |
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Term
| Most (but not all) radiation-induced cancers have which type of DRR? |
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Definition
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