Term
| MOA of levodopa/Carbidopa |
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Definition
levodopa is a precursor of dopamine. Carbidopa inhibits dopa decarboxylase, preventing peripheral metabolism of levodopa |
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Term
| Brand name for carbidopa/levodopa |
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Definition
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Term
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Definition
Statment. Not a question.
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Term
| Brand name for entacapone |
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Definition
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Term
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Definition
COMT - Inhibitor.
Used only with Levodopa to increase Levodopa Duration of Action. Inhibits the enyzme COMT to prevent peripheral conversion of levodopa. |
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Term
| Brand name for levodopa/carbidopa + entacapone |
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Definition
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Term
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Definition
| Statement. Not a question. |
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Term
| Brand name for Pramipexole |
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Definition
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Term
| Brand name for Ropinirole |
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Definition
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Term
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Definition
| Statment. Not a question. |
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Term
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Definition
| Statement. Not a question. |
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Term
| Levodopa/Carbidopa (sinemet) is contraindicated with what medications? |
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Definition
contraindicated with non - selective MAO - inhibitors (2 week separation) |
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Term
| Levodopa/Carbidopa sholdn't be used with dopamine blockers because? |
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Definition
will worsen disease symptoms - this includes phenothiazine, metoclopramide, etc |
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Term
| What can signficantly decrease the absoprtion of levodopa/carbidopa? |
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Definition
| Iron and Protein - rich foods can decrease absorption. |
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Term
| Can levodopa/carbidopa turn the color of urine? |
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Definition
Yes. May cause the urine to become darker, even dark brown, and can stain clothing. |
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Term
| How is apomorphine administered? |
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Definition
| given by subcutaneous (SC) injection. Never inject into a vein. |
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