Term
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Definition
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Term
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Definition
- synthetic catecholamine, primarily stimulates beta 1 adrenergic receptors
- positive inotropic, minimal chronotropic activity or systemic vascualr resistance
- useful in management of CHF when increased heart rate is not desired
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Term
Dobutamine - onset and duration
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Definition
onset: 1-2 minm peak after 10 min
duration: 10-15 min |
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Term
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Definition
| inotropic support for pt's with left ventricular dysfunction |
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Term
| Dobutamine - contraindications |
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Definition
- tachydysrhythmias (a-fib, a-flutter)
- severe hypotension with signs of shock
- idiopathic hypertrophic subartic stenosis
- suspected . known drug-induced shock
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Term
| Dobutamine - adverse reactions |
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Definition
- headache
- hypotension
- dose related tachydysrhythmias
- ventricular ectopy
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Term
| Dobutamine - drug interactions |
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Definition
- beta adrenergic antagonists - may blunt inotropic response
- sympathomimetrics and phosphodiesterase inhibitors - may exacerbate dysrhythmia response
- incompatible with sodium bicarb and furosemide - forms ppt - use different line
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Term
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Definition
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Term
Dobutamine - dosage and administration
Adult |
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Definition
| 2-20mcg/kg/min IV, based on inotropic effects |
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Term
Dobutamine - dosage and administration
pediatric |
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Definition
| 2-20mcg/kg/min IV/IO, titrate to effect |
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Term
| Dobutamine - special considerations |
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Definition
- preg. cat. : C
- admin via infusion pump
- may be admin through y site concurrent with dopamine, lidocaine, nitro pusside, KCl
- monitor BP closely
- increased heart rate more than 10% may induce/exacerbate MI
- have lido readily available
- correct hypovolemia before admin in hypotensive pt's
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