(Total Daily Dose)

• 0.5 units/kg

• 28 days
• Levemir 42 days

• 28 days
• Levemir 42 days

Insulin timing

• Rapid acting

Insulin timing

• Short acting

Insulin timing

• Intermediate acting

2/3 TDD

• 2/3 AM dose = intermediate (NPH)
• 1/3 AM dose = Short (regular)

1/3 TDD

• 2/3 PM dose = intermediate (NPH)
• 1/3 PM dose = Short (regular)

(1:1 acceptable as well)

Basal dose

(Long Acting)

1/2 TDD

Glargine or Detemir

QD

Bolus dose

• Rapid/Short acting

1/2 TDD

Divided evenly TID

or

20% TDD Breakfast, 15% Lunch, 15% Dinner

• NPH

• Glargine (Lantus)
• Detemir (Levemir)

• Lispro (Humalog)
• Aspart (Novolog)
• Glulisine (Apidra)

Insulin carbohydrate ratio

• 500 ÷ TDD=x
• 1:x = For every Xg of carbs, 1 unit of novolog (bolus) needed to neutralize

Insulin sensitivity function

• 1800 ÷ TDD

Insulin sensitivity function

• 1500 ÷ TDD