Term
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Definition
Thiazide diuretic
mechanism- Na and Cl transport out of the tubule by binding to the Cl site at the beginning of the DCT
side effect- dec. Ca2+ excretion, hypokalemia, inc. serum LDL and triglycerides, dec. uric acid secretion, inhibit insulin secretion |
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Term
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Definition
Thiaside diuretic
mechanism- Na and Cl transport out of the tubule by binding to the Cl site at the beginning of the DCT
side effect- dec. Ca2+ excretion, hypokalemia, inc. serum LDL and triglycerides, dec. uric acid secretion, inhibit insulin secretion |
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Term
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Definition
Loop diuretic
mechanism- inhibit Na and Cl reabsorption in the ascending loop of Henle, cause more Na retention
S.E.- dehydration, hypokalemia, inc. Ca2+ excretion, cause auditory nerve damage |
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Term
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Definition
Loop diuretic
mechanism- inhibit Na and Cl reabsorption in the ascending loop of Henle, cause more Na retention
S.E.- dehydration, hypokalemia, inc. Ca2+ excretion, cause auditory nerve damage |
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Term
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Definition
Loop diuretic
mechanism- inhibit Na and Cl reabsorption in the ascending loop of Henle, cause more Na retention
S.E.- dehydration, hypokalemia, inc. Ca2+ excretion, cause auditory nerve damage |
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Term
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Definition
Loop diuretic
mechanism- inhibit Na and Cl reabsorption in the ascending loop of Henle, cause more Na retention
S.E.- dehydration, hypokalemia, inc. Ca2+ excretion, cause auditory nerve damage |
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Term
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Definition
Aldosterone Antagonist- potassium sparing diuretic
mechanism- block aldosterone receptors, prevent the synthesis of the Na K exchanger
S.E.- hyperkalemia, causes dec. synthesis of testosterone and inc. its metabolism- causes gynecomastia |
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Term
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Definition
Aldosterone Antagonist- potassium sparing diuretic
mechanism- block aldosterone receptors, prevent the synthesis of the Na K exchanger
S.E.- hyperkalemia |
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Term
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Definition
potassium sparing diuretic
mechanism-prevents Na from entering the principle cells and reaching the exchanger
S.E.- hyperkalemia, more rapid and predictable than aldosterone analogs |
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Term
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Definition
potassium sparing diuretic
mechanism-prevents Na from entering the principle cells and reaching the exchanger
S.E.- hyperkalemia, more rapid and predictable than aldosterone analogs |
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Term
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Definition
Carbonic anhydrase inhibitor
mechanism-prevents HCO3 resorption from the PCT
S.E.- metabolic acidosis
Use- used for open angle glaucoma, mountain sickness, epilepsy, alkalinized urine |
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Term
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Definition
osmotic diuretic
mechanism- sugar that gets into tubule and cannot be resorbed and causes water to flow out of the tubules
S.E.- maintains urine flow after traumatic injury and lowers intracranial pressure |
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Term
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Definition
Caffeine
mechanism- inc. GFR, in CO |
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Term
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Definition
| mechanism- inhibits release of ADH, prevents reabsoption of H20 from the tubule |
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