Term
|
Definition
Chlorothiaziade
Na/Cl Symporter Inhibitor
Works on site 3
increase K excretion
inc Ca reablsorbtion
No GFR change |
|
|
Term
|
Definition
HCTZ
Also known as Hydrodiuril, and Oretic
Na/Cl Symporter Inhibitor
Works on site 3
increase K excretion
inc Ca reablsorbtion
No GFR change
Does NOT alter medullary/countercurrent |
|
|
Term
|
Definition
Polythiazide
Na/Cl Symporter Inhibitor
Works on site 3
increase K excretion
inc Ca reablsorbtion
No GFR change |
|
|
Term
|
Definition
Chlorthalidone
Na/Cl Symporter Inhibitor
Works on site 3- Distal Tubule
increase K excretion
inc Ca reablsorbtion
No GFR change |
|
|
Term
|
Definition
Metolazone
Na/Cl Symporter Inhibitor (Thiazide Diuretic)
Works on site 3
increase K excretion
inc Ca reablsorbtion
No GFR change |
|
|
Term
|
Definition
Indapamide
Na/Cl Symporter Inhibitor
Works on site 3
increase K excretion and Ca reablsorbtion
No GFR change
thiazide |
|
|
Term
|
Definition
Ethacrynic Acid
Inhibitor of Na/K/2Cl symporter
Loop Diuretic
Works on site 2- TAL
Proximal to macula densa
eliminates Na and H2O
Decreases preload
retention of uric acid
Interferes with countercurrent |
|
|
Term
|
Definition
Bumetanide
Inhibitor of Na/K/2Cl symporter
Loop Diuretic
Works on site 2- TAL
Proximal to macula densa
Excretion of Na, Cl, K and Ca2+
Decreases preload
retention of uric acid
Interferes with countercurrent
Acts on luminal side, secreted by PT
Increases release of renal Prostaglandins
|
|
|
Term
|
Definition
Torsemide
Inhibitor of Na/K/2Cl symporter
Loop Diuretic
Works on site 2- TAL
Proximal to macula densa
Excretion of Na, Cl, K and Ca2+
Decreases preload
retention of uric acid
Interferes with countercurrent
Acts on luminal side, secreted by PT
Increases release of renal Prostaglandins |
|
|
Term
|
Definition
Eplerenone
Antagonist of mineralocorticoid receptors
K-sparing Diuretic |
|
|
Term
|
Definition
Amiloride
K-sparing Diuretic
Inhibitor of renal epithelial Na Channel
Site 4 |
|
|
