Term
|
Definition
| Thiazide Diuretic- prototype, TX for hypertension and CHF |
|
|
Term
| Hydrochlorothiazide (HCTZ) |
|
Definition
| Thiazide Diuretic- thiazide derivative, more popular, more potent |
|
|
Term
|
Definition
| Thiazide Diuretic- thiazide derivative behaves like HCTZ, long duration, TX for HTN. better outcomes? |
|
|
Term
|
Definition
| Thiazide Diuretic Analog- lipid soluble, nonthiazide diuretic with long duration of action. Direct arterial vasodilation. Can be used in renal disease |
|
|
Term
|
Definition
| Thiazide Diuretic Analog- can be used in pt's with renal disease, drug does not rely on secretory process. More potent |
|
|
Term
|
Definition
| Loop Diuretic- high efficacy, DOC for reducing acute pulmonary edema of CHF, useful for hypercalcemia |
|
|
Term
|
Definition
| Loop Diuretic- high efficacy, DOC for reducing acute pulmonary edema of CHF, useful for hypercalcemia |
|
|
Term
|
Definition
| Loop Diuretic- high efficacy, DOC for reducing acute pulmonary edema of CHF, useful for hypercalcemia |
|
|
Term
|
Definition
| Loop Diuretic- high efficacy, DOC for reducing acute pulmonary edema of CHF, useful for hypercalcemia, higher AE of ototoxity |
|
|
Term
| Spironolactone (Aldactone) |
|
Definition
| Potassium Sparing Diuretic- competes with the aldosterone action & can overcome K+ deficiency. Synthetic aldosterone antagonist, most effetive for mild edema few days at a time |
|
|
Term
|
Definition
| Potassium Sparing Diuretic- Aldosterone antagonist, less Estrogenic/steroid adverse effects |
|
|
Term
|
Definition
| Potassium Sparing Diuretic- decrease in Na/K exchange. Doesn't depend on aldosterone |
|
|
Term
|
Definition
| Potassium Sparing Diuretic- acts to retain K+, decrease in Na/K exchange. Doesn't depend on aldosterone |
|
|
Term
|
Definition
| Osmotic Diuretic- maintain urine flow following ingestion of toxic substances that produce renal failure, TX for increased ICP, (IV) |
|
|
Term
|
Definition
| Osmotic Diuretic- maintain urine flow following ingestion of toxic substances that produce renal failure, TX for increased ICP |
|
|
Term
|
Definition
| Carbonic Anhydrase Inhibitor- involved in the na/k/h exchange in proximal convoluted tubule, acidosis; weak diuretic. used for open angle glaucoma and mountain sickness |
|
|
Term
|
Definition
| increase the urine volume, results in water loss; does not affect Na |
|
|
Term
|
Definition
| block reabsorption of Na at the Loop of Henle |
|
|
Term
|
Definition
| block reabsorption of Na at the distal tubule |
|
|
Term
| Diuretic increase Ca++ reabsorption |
|
Definition
|
|
Term
| Diuretic causes loss of Ca++ |
|
Definition
|
|
Term
| Potassium- Sparing Diuretic MOA |
|
Definition
| Inhibit Na+ reabsorption, K+ secretion, & H+ secretion in the collecting tubule |
|
|
Term
|
Definition
| filters through the glomerulus, increase water excretion rather than Na+ excretion |
|
|
