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        | Potassium-sparing diuretics |  | Definition 
 
        | has a direct effect on the distal tubules in the kidney.  Competes with Aldosterone for cell-receptor sites in the distal tubules while inducing excretion of sodium and reducing excretion of potassium and hydrogen ions. |  | 
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        | Term 
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        | Inhibit sodium and chloride reabsorption through direct action primarily in the ascending loop of Henle (and minimally in the proximal and distal tubules). |  | 
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        | Term 
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        | Acts primarily on the distal tubules, inhibiting Na and Cl reabsorption. |  | 
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