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DIT Quizzes Day 8.1
Oncology
65
Other
Professional
05/18/2013

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Cards

Term
What kind of vaccine uses a live virus that has lost its virulence?
Definition
Live-attenuated vaccine
Term
What are some examples of live vaccines?
Definition
MMR, Sabin (polio), VZV vaccine, yellow fever vaccine, intranasal influeza, small pox
Term
Which HIV meds cause pancreatitis
Definition
Ritonavir, Stavudine, Didanosine, Zalcitabine
Term
Which HIV meds cause rash?
Definition
NNRTIs
Term
WHich HIV meds cause peripheral neuropathy?
Definition
Stavudine, Didanosine, Zalcitabine
Term
Which antibiotics are safe during pregnancy?
Definition
Cell wall inhibitors
Macrolides
Metronidazole after 1st trimester
Nitrofurantoin
Term
What neoplasms are associated with Hashimoto's thyroiditis?
Definition
Lymphoma
Term
What neoplasms are associated with Down's syndrome?
Definition
ALL and AML
Term
What neoplasms are associated with Plummer-Vinson syndrome?
Definition
Squamous cell carcinoma of the esphagus
Term
What neoplasms are associated with Tuberous sclerosis
Definition
Astocytoma
Angiomyolipoma
Cardiac rhabdomyoma
Term
What neoplasms are associated with Ataxia Telangiectasia?
Definition
lymphoma, acute leukemia
Term
What neoplasms are associated with Paget's disease of bone
Definition
Secondary osteosarcoma and fibrosarcoma
Term
What type of cancer is a/w the following tumor suppressor gene:
Rb
Definition
Retinoblastoma
Osteosarcoma
Term
What type of cancer is a/w the following tumor suppressor gene:
DPC
Definition
Pancreatic cancer
Term
What type of cancer is a/w the following tumor suppressor gene:
p53
Definition
Most human cancers, Li-Fraumeni syndrome
Term
What type of cancer is a/w the following tumor suppressor gene:
APC
Definition
Colorectal cancer (FAP)
Term
What type of cancer is a/w the following tumor suppressor gene:
WT1
Definition
Wilm's tumor
Term
What type of cancer is a/w the following tumor suppressor gene:
BRCA 1 and BRCA 2
Definition
1: Breast and ovarian cancer
2: Breast cancer
Term
Which neoplasm is a/w the following statement:
Nitrosamines (smoked foods)
Definition
Gastric cancer
Term
Which neoplasm is a/w the following statement:
Asbestosis
Definition
Mesothelioma and brochogenic carcinoma
Term
Which neoplasm is a/w the following statement:
Naphthalene
Definition
transitional cell carcinoma of the bladder
Term
Which neoplasm is a/w the following statement:
Arsenic
Definition
Squamous cell carcinoma, angiosarcoma
Term
Which neoplasm is a/w the following statement:
EBV
Definition
Burkitt lymphoma, Hodgkin's lymphoma, nasopharyngeal carcinoma
Term
Which neoplasm is a/w the following statement:
HPV
Definition
Cervical carcinoma, penis/anal carcinoma
Term
Which neoplasm is a/w the following statement:
Schistosoma haematobium
Definition
Squamous cell carcinoma of transitional epithelium (bladder)
Term
Which tumor marker would you use to follow hepatocellular carcinoma
Definition
AFP
Term
Which tumor marker would you use to follow ovarian cancer
Definition
CA-125
Term
Which tumor marker would you use to follow pancreatic cancer
Definition
CA-19-9
Term
Which tumor marker would you use to follow melanoma
Definition
S-100
Term
Which tumor marker would you use to follow colon cancer
Definition
CEA
Term
Which tumor marker would you use to follow astrocytoma
Definition
S-100
Term
What is the most common cause of hypercalcemia? What cancers may cause hypercalcemia
Definition
Most common cause: Primary hyperparathyroidism and malignancies

Cancers: Squamous cell lung carcinoma, renal cell carcinoma, breast carcinoma, multilple myeloma
Term
What neoplasm is most commonly responsible for the paraneoplastic syndrome:
ACTH--> Cushing syndrome
Definition
Small cell lung carcinoma
Term
What neoplasm is most commonly responsible for the paraneoplastic syndrome:
Erythropoiestin--> polycythemia
Definition
Renal cell carcinoma, hemangioblastoma, hepatocellular carcinoma, pheochromocytoma
Term
What neoplasm is most commonly responsible for the paraneoplastic syndrome:
ADH--> SIADH
Definition
Small cell lung carcinoma, intracranial neoplasms
Term
Which anticancer drug fits the following description:
Forms a complex between topoisomerase and DNA
Definition
Etoposide
Term
Which anticancer drug fits the following description:
Akylates DNA; Toxicity = pulmonary fibrosis
Definition
Busulfan
Term
Which anticancer drug fits the following description:
Framents DNA; Toxicity = pulmonary fibrosis
Definition
Bleomycin
Term
Which anticancer drug fits the following description:
Blocks purine synthesis; metabolized by xanthine oxidase
Definition
6-mercaptopurine
Term
Which anticancer drug fits the following description:
Cross-links DNA; nephrotoxic, ototoxic
Definition
Cisplatin
Term
Which anticancer drug fits the following description:
Nitrogen mustard, alkylates DNA (electrophil that binds DNA)
Definition
Cyclophosphamide
Term
Which anticancer drug fits the following description:
Folic acid analog that inhibits dihydrofolate reductase
Definition
Methotrexate
Term
Which anticancer drug fits the following description:
Prevents tubulin disassembly
Definition
Paclitaxel
Term
Which anticancer drug fits the following description:
Intercalates DNA, produces oxygen free radicals, cardiotoxic
Definition
Doxorubicin
Term
Which anticancer drug fits the following description:
DNA alkylating agents used in brain cancer
Definition
Nitrosoureas
Term
Which anticancer drug fits the following description:
Prevents tubulin assembly
Definition
Vincristine, vinblastine
Term
Which anticancer drug fits the following description:
inhibits thymidylate synthase, decreasing nucleotide synthesis
Definition
5-Fluorouracil
Term
Which anticancer drug fits the following description:
SERM, blocks estrogen binding to ER+ cells
Definition
Tamoxifen, raloxifen
Term
Which anticancer drug fits the following description:
Mechanism similar to antivirals acyclovir and foscarnet
Definition
Cytarabine
Term
Which anticancer drug fits the following description:
Mechanism similar to fluoroquinolones
Definition
Etoposide
Term
Which anticancer drug fits the following description:
Mechanism similar to trimethoprim
Definition
Methotrexate
Term
Which anticancer drug fits the following description:
Monoclonal antibody against HER-2
Definition
Trastuzumab
Term
Which anticancer drug fits the following description:
Free radical induced DNA strand breakage
Definition
Bleomycin, Doxirubicin
Term
Which anticancer drug fits the following description:
Inhibitor of PRPP synthetase
Definition
6-mercaptopurine
Term
Which anticancer drug fits the following description:
Reversible with leucovorin
Definition
Methotrexate
Term
Which anticancer drug fits the following description:
Treatment for choriocarcinoma
Definition
Methotrexate, Vincristine, Vinblastine
Term
Which anticancer drug fits the following description:
Treats AML
Definition
Cytarabine
Term
Which anticancer drug fits the following description:
Treats CML
Definition
Busulfan
Term
Which anticancer drug fits the following description:
Prevents breast cancer
Definition
Tamoxifen, Roloxifen
Term
Which anticancer drug fits the following description:
Treatment for testicular cancer (3)
Definition
Etoposide
Bleomycin
Cisplatin
Term
Which anticancer drug fits the following description:
Applied topically for AKs and basal cell carcinoma
Definition
5-fluorouracil
Term
Which anticancer drug fits the following description:
Treatment for childhood tumors
Definition
Dactinomycin
Term
Which anticancer drug fits the following description:
Inhibits ribonucleotide reductase
Definition
Hydroxyurea
Term
Which anticancer drug fits the following description:SE = hemorrhagic cystitis
Definition
Cyclophosphamide
Term
Which anticancer drug fits the following description:
Antibody against Philadelphia chromosome
Definition
Imatinib
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