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DIT Quizzes Day 10.1 & 10.2
Female reproduction
96
Other
Professional
05/22/2013

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Term
where can you find nicotinic acetylcholine receptors in the body?
Definition
NMJ, and autonomic ganglion
Term
What are the functions of interleukins 1-5?
Definition
IL-1: Fever
IL-2: Induce T-cell proliferation
IL-3: Promote bone marrow stimulation
IL-4: Induce B cells--> IgE, IgG
IL-5: Induce B cells--> IgA, eosinophils
Term
What changes in sleep patterns and sexual anatomy are seen in the elderly?
Definition
decreased REM
decreased slow wave sleep
increased sleep latency
increased night time awakenings
Term
What is the main difference between delirium and dementia? Which on is more commonly reversible?
Definition
Delirium is reversible, rapid onset, includes alterations in consciousness

Dementia is irreversible, usually progressive slow onset, no alterations in consciousness
Term
What are the layers of the epidermis?
Definition
From outer to inner
Corneum
Lucidum
Granulosum
Spinosum
Basalis
Term
Where would you expect to find B cells and T cells in the spleen? In the lymph nodes?
Definition
Spleen: B cells= follicles
Tcells= PALS (Periarterial lymphatic sheath)

Lymph nodes: B cells= follicles
Tcells= pericortex
Term
What structures arise from the paramesonephric ducts?
Definition
Fallopian tube, uterus, upper portion of vagina
Term
What changes in sexual anatomy are seen in the elderly?
Definition
Males: slower erection/ ejaculation
Longer refractory period

Females: atrophic vaginitis
Term
What are the different mechanisms by which heart contractility can be increased?
Definition
Catecholamines (stress, exercise)
Increased intracellular Ca
Decreased intracellular Na
Digoxin
Term
What pathology:
Smudge cells
Definition
CLL
Term
What pathology:
Port-wine stain on ophthalmic division of trigeminal nerve
Definition
Srugg-Weber syndrome
Term
What pathology:
S3 heart sound
Definition
Dilated cardiomyopathy
LV failure
Mitral regurg
L-->R shunt
Term
What pathology:
Cardiac tumor in a child with tuberous sclerosis
Definition
Rhabdomyoma
Term
What pathology:
Adrenal hemorrhage with meningococcemia
Definition
Waterhouse-Friderichsen syndrome
Term
What pathology:
Ferruginous bodies
Definition
Asbestosis
Term
What pathology:
Subepithelial humps on EM
Definition
Post-streptococcal glomerulonephritis
Term
What pathology:
Myocyte disarray
Definition
Hypertrophic cardiomyopathy
Term
What pathology:
Current jelly stool
Definition
intussusception
Term
What pathology:
Sacroilitis
Definition
ankylosing spodylitis
Term
What pathology:
Adverse reaction from mixing succinylcholine with inhaled anesthetics
Definition
malignant hyperthermia
Term
Which antihypertensive drug had the following SE:
First dose orthostatic hypotension
Definition
a1-blockers (-zosins)
Term
Which antihypertensive drug had the following SE:
Hypertrichosis
Definition
Minoxidil
Term
Which antihypertensive drug had the following SE:
Cyanide toxicity
Definition
Nitroprusside
Term
Which antihypertensive drug had the following SE:
Dry mouth, sedation, severe rebound HTN
Definition
Clonidine
Term
Which antihypertensive drug had the following SE:
Bradycardia, impotence, asthma exacerbation
Definition
B-blockers
Term
Which antihypertensive drug had the following SE:
Reflex tachycardia
Definition
Nitrates, CCBs, minoxidil
Term
Which antihypertensive drug had the following SE:
Metabolic alkylosis
Definition
Loop diuretics
Term
Which antihypertensive drug had the following SE:
Elevated antihistone antibodies
Definition
Hydralazine (drug induced lupus)
Term
Which antihypertensive drug had the following SE:
Hypercalcemia
Definition
Thiazide diuretic
Term
What cancers are associated with the following tumor marker:
PSA
Definition
Prostate cancer
Term
What cancers are associated with the following tumor marker:
AFP
Definition
Hepatocellular carcinoma, yolk sac tumors
Term
What cancers are associated with the following tumor marker:
CA-125
Definition
Ovarian cancer
Term
What cancers are associated with the following tumor marker:
Elevated alk-phos
Definition
Paget's disease Mets to bone Biliary disease
Term
What pathology is a/w the following tumor marker: CEA
Definition
Colon cancer, colorectal cancer, pancreatic cancer, stomach cancer
Term
What cancers are associated with the following tumor marker:
bhCG
Definition
choriocarcinoma, hydatidiform mole
Term
What cancers are associated with the following tumor marker:
S-100
Definition
Melanoma, astrocytoma, some neural tumors
Term
What structures are at risk for injury with anterior shoulder dislocation
Definition
Axillary nerve Posterior circumflex artery Glenoid labrum Supraspinatus tendon Anterior glenohumeral ligament Posterolateral humeral head
Term
What is the rate limiting step in purine synthesis?
Definition
Glutamine PRPP aminotrasferase
Term
What is the rate limiting step in pyrimadine synthesis?
Definition
CPS II
Term
What drugs should not be given to patients with sulfa allergy?
Definition
Celecoxib, furosemide, thiazides, acetazolamide, probenecid, sulfonamide abx, sulfonylureas, sulfasalazine
Term
Which hypothalamic nucleus is involved in ovulation
Definition
arcuate nucleus releases GnRH
Term
When does basal body temperature increase in relation to ovulation?
Definition
24 hours after ovulation
Term
What uterine pathology:
Excess unopposed estrogen is the main risk factor
Definition
Endometrial hyperplasia/ Endometrial carcinoma
Term
What uterine pathology:
Menorrhagia with an enlarged uterus and and no pelvic pain
Definition
Leiomyoma
Term
What uterine pathology:
Pelvic pain that is present only during menstruation
Definition
Endometriosis
Term
What uterine pathology:
Diagnosed by endometrial biopsy in clinic
Definition
Endometrial hyperplasia/ Endometrial carcinoma
Term
What uterine pathology:
Definitive diagnosis and treatment is by laproscopy
Definition
Endometriosis
Term
What uterine pathology:
Menstruating tissue within the myometrium
Definition
Adenomyosis
Term
What uterine pathology:
Malignant tumor of the uterine smooth muscle
Definition
Leiomyosarcoma
Term
What uterine pathology:
Most common gynecological malignancy
Definition
Endometrial carcinoma
Term
What is the difference between placenta previa, accreta, and abruptio?
Definition
Abruptio: premature detachment of the placenta; painful bleeding

Previa: abnormal placentation to the lower uterine segment; painless bleeding

Accreta: defective decidual layer allows placenta to attach directly to the myometrium; massive bleeding after delivery
Term
For what is a pregnant woman with a previous C section is at risk?
Definition
Placenta previa, placenta accreta (due to scarring)
Term
A pregnant woman at 16 weeks of gestation presents with an atypically large abdomen and hypertension. What abnormality may be seen on the blood test, what is the dx?
Definition
Excessively elevated beta-hCG; Hydatidiform mole (molar pregnancy)
Term
What substance is present in high levels in hydatidiform mole
Definition
beta-hCG
Term
A 15 year old female patient of yours that normally comes in with her parents presents alone this time. She states that she is sexually active but knows that she is not pregnant because she has never menstruated. What would be the most appropriate next step in managing this patient
Definition
Assess for delayed puberty
Educate on safe sex, and that it is possible to get pregnant before first period
Offer birth control
Term
A 23 year old female who is on rifampin for TB prophylaxis and birth control gets pregnant. Why?
Definition
Rifampin induce p450 so the OCPs are metabolized faster, therefore less effective
Term
What is the best option for birth control in a mentally retarded patient
Definition
IM medroxyprogesterone
Term
What breast pathology fits the following:
Most common breast tumor in women under 25
Definition
Fibroadenoma
Term
What breast pathology fits the following:
Most common breast mass in postmenopausal women
Definition
Invasive ductal carcinoma
Term
What breast pathology fits the following:
Most common breast mass in premenopausal women
Definition
Fibrocystic disease
Term
What breast pathology fits the following:
Most common form of breast cancer
Definition
Invasive ductal
Term
What breast pathology fits the following:
Small, mobile, firm mass in 24 year old woman
Definition
Fibroadenoma
Term
What breast pathology fits the following:
Histological leaf-like projections
Definition
Phyllodes tumor
Term
What breast pathology fits the following:
Signet ring cells
Definition
Lobular carcinoma in situ, invasive lobular carcinoma
Term
What breast pathology fits the following:
Loss of e-cadherin cell adhesion gene on chromosome 16
Definition
Invasive lobular
Term
What breast pathology fits the following:
Always ER+ and PR+
Definition
Lobular carcinoma in situ
Term
What breast pathology fits the following:
Commonly presents with nipple discharge
Definition
intraductal papilloma
Term
What breast pathology fits the following:
Eczematous patches on nipple
Definition
Paget's disease of the nipple
Term
What breast pathology fits the following:
Multiple bilateral fluid filled lesions with diffuse breast pain
Definition
cystic fibrocystic disease
Term
What breast pathology fits the following:
Firm, fibrous mass in a 55 year old woman
Definition
Invasive ductal carcinoma
Term
What are the target cells of LH
Definition
Theca cells, Leydig cells
Term
What cells respond to FSH
Definition
Sertoli cells (male), Granulosa cells
Term
State whether the following agent describes estrogen or progesterone:
Production of thick mucus that inhibits entry of sperm into the uterus
Definition
Progesterone
Term
State whether the following agent describes estrogen or progesterone:
Induces LH surge
Definition
Estrogen
Term
State whether the following agent describes estrogen or progesterone:
Uterine smooth muscle relaxation
Definition
Progesterone
Term
State whether the following agent describes estrogen or progesterone:
Follicle growth
Definition
Estrogen
Term
State whether the following agent describes estrogen or progesterone:
Maintenance of pregnancy
Definition
Progesterone
Term
State whether the following agent describes estrogen or progesterone:
Hepatic synthesis of transport proteins
Definition
Estrogen
Term
State whether the following agent describes estrogen or progesterone:
Withdrawal leads to menstruation
Definition
Progesterone
Term
What drug would you give to inhibit prolactin secretion
Definition
Dopamine agonist (bromocriptine, cabergoline)
Term
When does b-hCG appear in the urine during pregnancy
Definition
2 weeks after conception
Term
What hormonal changes are seen during menopause?
Definition
Decreased estrogen
Elevated LH
Elevated FSH
Elevated GnRH
Term
What is the underlying cause of PCOS? What are the clinical manifestations and treatment
Definition
Elevated LH production;
enlarged cystic ovaries, hirsutism, obesity, infertility, amenorrhea
Tx: weight reduction, OCPs, medroxyprogesterone, spironolactone, clomiphene (for women who want to get pregnant)
Term
What ovarian tumor produces AFP
Definition
Yolk sac tumor
Term
What ovarian tumor secretes estrogen causing precocious puberty?
Definition
Granulosa theca cell tumor
Term
What ovarian tumor is characterized by intraperitoneal accumulation of mucinous material
Definition
mucinous cystadenoma
Term
What ovarian tumor secretes testosterone causing virilization
Definition
Sertoli leydig
Term
What ovarian tumor is characterized psammoma bodies
Definition
serous ovarian cancer
Term
What ovarian tumor includes multiple different tissue types
Definition
teratoma
Term
What ovarian tumor is lined with fallopian tube-like epithelium
Definition
Serous cystadenoma
Term
What ovarian tumor:
Ascites + hydrothorax + ovarian tumor
Definition
Meigs' Syndrome (fibromas)
Term
What ovarian tumor is characterized by Call-Exner bodies
Definition
Granulosa cell tumor
Term
What ovarian tumor resembles bladder epithelium
Definition
Brenner tumor
Term
What ovarian tumor is characterized by elevated Beta-hCG
Definition
Choriocarcinoma
Term
What are the risk factors for endometrial carcinoma?
Definition
elevated estrogen
PCOS, obesity, estrogen secreting tumor, HRT, age, endometrial hyperplasia
Term
What are the risk factors for ovarian carcinoma?
Definition
Ovulation,early menarche, late pregnancy, late menopause
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