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DIT High Yield COMLEX 2
DIT High Yield COMLEX 2
254
Medical
Professional
06/16/2015

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Term
MCC Bacterial Meningitis in NEONATES & Preferred treatment
Definition
E. coli
GBS
Listeria
Tx w/ AMpicillin + cefotaxime or gent

Term
MCC Bacterial Meningits in 1 mo- 60 yo & tx
Definition
S. pneumo
N. meningitidis
(H. flu)

Tx w/ Cefotaxime or ceftriaxone + vanco+ dexamethasome IV
Term
MCC Bacterial meningitis in > 60 y/o & tx
Definition
S. pneumo
Listeria
N. meningitidis
G- bacilli
Tx w/ ampicillin (listeria coverage) + Cefotaxime or ceftriaxone + vanco + dexamethasone
Term
G+ diplococci
Definition
S. pneumo
Term
G- diplococci
Definition
N. meningitidis
Term
G- coccobacilli
Definition
H. flu
Term
G+ rods and coccobacilli
Definition
Listeria
Term
Prophylaxis for close contacts of bacterial meningitis
Definition
Rifampin or Cipro
Term
MCC AIDS meningitis
Definition
cryptococcal meningitis
dx w/ india ink stain
tx w/ Amp B
Term
ACA stroke s/s
Definition
leg, feet, trunk sensory + motor deficit (contralateral)
Term
MCA stroke s/s
Definition
arm, face, hands motor + sensory deficit (contralateral)
Term
PCA stroke s/s
Definition
visual changes with macular sparing
Term
Basilar artery stroke s/s
Definition
cranial nerve palsies, contralateral full body weakness 2/2 CST decussation at medullary pyramids
Possible coma if RAS affected
Term
Treatment for SAH
Definition
1. Labetolol (control HTN)
2. Nimodipine (Prevent vasospasm)
3. Clip/coil bleeder
4. stop anticoagulants
Term
Tx pf absence sz
Definition
ethosuximide
Term
ASE gingival hyperplasia
Definition
phenytoin
Term
Tx for trigeminal neuralgia
Definition
carbamazepine
Term
CYP 450 INDUCERS
Definition
"Keyntoin Rides Shotgun in Barbie's Girl Car
Phenytoin
Rifampin
St Johns Wort
Barbiturates
Griseofulvin
Carbamazepine
Term
Tx Parkinson's
Definition
Levodopa + carbidopa
selegiline
Bromocriptine
Term
Tx ALS
Definition
Riluzole
Term
Tx Nephrogenic DI from lithium
Definition
Amiloride
Term
S/S Lew Body Dementia
Definition
dementia
parkinsonism
visual hallucinations
Term
S/S Pick disease (frontotemporal dementia)
Definition
dementia
personality/behavior changes
proressive asphasia
Term
Bilateral upper and lower facial paralysis
Definition
Bell's palsy
Term
When do night terrors occur
Definition
stage N3 sleep (non-REM)
Term
Most common brain tumors in Adults
Definition
"MGM Studios"
Mets
1. Glioplastoma
2. Meningioma
3. Schwaanoma
Term
Most common brain tumors in Peds
Definition
"Animal kingdom, Magic kingdom, Epcot center"
1. Astrocytoma
2. Medulloblastoma
3. Ependymoma
Term
Broca's broken boca location of stroke
Definition
MCA, frontal lobe
Term
Diseases assoc w/ uveitis
Definition
HLA-B27 Seronegative Arthropathies (PAIR)
- Psoriatic arthritis
- Ankylosing spondylitis
- IBD (UC)
- Reactive arthritis (Reiter's syndrome)

+ Juvenile Rheumatoid
Term
Pt has severe eye pain, redness and inflamed eye, hard orbit and dilated pupil. Whats the dx?
Definition
Acute closed angle glaucoma
Term
Major PE finding for open-angle glaucoma?
Definition
Cupping of optic disc (2:1)
Term
DDx Cherry red spot on macula
Definition
Tay Sachs
Neiman Pick
Retinal Artery Occlusion
Term
Lens dislocation ddx
Definition
Upward: Marfan's
Downward: Homocystinuria
Alport Syndrome
Term
Hearing Loss
Tinnitus
Vertigo
Definition
Meniere's disease
Term
SIG E CAPS
Definition
SLEEP disturbances
loss of INTEREST
GUILT
lack of ENERGY
Poor CONCENTRATION
APPETITE changes
PSYCHOMOTOR retardation/agitation
SUICIDAL ideation
Term
Antibodies in Type I DM
Definition
Anti-Insulin (IAA)
Anti-islet cell cytoplasm (ICA)
anti-glutamic acid decarboxylase (GAD)
Anti-tyrosine phosphatase (IA-2)
Term
DM med contraindicated in CHF
Definition
TZD (pioglitazone)
Term
ASE Metform
Definition
Lactic acidosis
Term
TSI antibodies
(Thyroid stimulating immunoglobulin)
Definition
Grave's Dz --> PAINLESS goiter
Term
PAINFUL goiter
Definition
subactue thyroiditis (deQuervains)
Term
Anti-thyroid peroxidase abs
Anti-thyroglobulin abs
Definition
Hashimoto's thyroiditis --> PAINLESS goiter
Term
Triad in HypERaldosteronism
Definition
HTN
Hypokalemia
Metabolic Alkalosis
(Increased Na+)
Term
Congenital Adrenal Hyperplasia
If 1 in 1st digit=?
If 1 in 2nd digit =?
Definition
1 in 1st digit (11, 17): HTN

1 in 2nd digit (11, 21): virilization (F), large genitals (M)
Term
MEN1
(Wemer's syndrome)
Definition
-Diamond-
Pituitary
Parathyroid ademoma
Pancreas
(possible ZE syndrome, pituitary disorders: acromegaly, cushings syndrome, galactorrhea, etc)
Term
MEN2A
(Sipple syndrome)
Definition
-Square-
Parathyroid hyperplasia
Pheos
+Medillary thyroid cancer
Term
MEN2B
Definition
-Triangle-
Oral (Mucosal neuromas)
Pheos
+Medullary thyroid cancer
(often marfanoid body habitus)
Term
First sign of cretinism?
Definition
Prolonged jaundice
--> Cretinism causes MR and abn growth deveopment, signs of hypothyroidism
Term
S/S anticholinergic toxicity
Definition
mad as a hatter, hot as a hare, dry as a bone, red as a beet, blind as a bat, bloated as a toad and the heart runs alone
Term
Antidote of anticholinergic poisoning
Definition
Physostigmine (Phix atropine OD w/ Physostigmine)
Term
Tx cyanide posioning
Definition
Sodium thiosulfate
hydroxycobalamin (B12 precursor)
Amyl nitrate
Term
Antidote for acetaminophen poisoning
Definition
NAC
Term
S/S Aspirin OD
Definition
TINITUS
Hyperthermia
Alkalosis from hyperventilation --> then mixed rest all and met acid w/ wide AG
Term
Tx Aspirin OD
Definition
Charcoal/Bicarb/Dialysis
Term
Tx methemoglobinemia
Definition
methylene blue
Term
What should always be administrated with Isoniazid?
Definition
Vit B6 (pyridoxine)

DO NOT confuse w/ Pralidoxime --> organophosphate poisoning
Term
Antidote arsenic poisoning
Definition
Penicillamine, dimercaperol, or succimer
Term
Antidote Copper poisoning
Definition
Penicillamine
Term
Antidote Iron poisoning
Definition
Deferoxamine
Term
Antidote mercury poisoning
Definition
dimercaperol
Term
Antidote t-PA
Definition
aminocaproic acid
Term
Cushing's triad
Definition
HTN
Bradycardia
Decreased Respiratory Rate
Term
GCS Scale
Definition
4 - Eye Opening
4: Spontaneous
3: To Voice
2: To Pain
1: None
5 - Verbal Response
5: Oriented
4: Confused
3: Inappropriate words
2: Incomprehensible
1: None
6 - Motor Response
6: Obeys commands
5: Localizes pain
4: Withdraws from pain
3: Decorticate
2: Decerebrate
1: none
Term
Preferred location for Swan-Ganz
Definition
Left subclavian
Right internal jugular
Term
What pts are at higher risk of transfusion reaction?
Definition
IgA deficiency (preformed anti-IgA IgG antibodies
Tx: Epi, volume maintenance and airway, Repeat type and screen for both pt and donor's blood
Term
5 W's of Post Op Fever
Definition
Wind (POD1-2): Atelectasis/PNA
Water (POD3): UTI
Walking (POD5): DVT/PE
Wound (POD7): Infection
Wonder Drugs (anytime)
Term
Tx Malignant hyperthermia
Definition
Dantrolene
Term
Timeline and tx Hyperacute organ rejection
Definition
Initial 24 hours
Untreatable (should have been avoided by proper crossmatching)
Term
Timeline and tx Acute organ rejection
Definition
6 days-1 year
Antidonor T-cell proliferation
Reversible w/ immunosupression
Term
Timeline and tx Chronic organ rejection
Definition
>1 year
Cellular and hunmoral immune rxn to donor tissue
Untreatable
Term
Lens shaped bleed = ?
"Convex"
Definition
Epidural hematoma
Term
Crescent shaped bleed = ?
"Concave"
Definition
Subdural hematoma
Term
Classic HPI Epidural hematoma?
Definition
Injury
"LUCID INTERVAL"
deterioration (LOC, SZ, blown pupil, etc)
Term
MCC Otitis media
Definition
S. pneumo
H.flu
Moraxella
Term
S/S Acoustic schwannoma
Definition
Hearing loss
Dizziness
Tinnitus
Unilateral facial palsy
MRI to localize tumor
Term
Anterior (& anterioseptal) Wall MI (Leads and vessel)
Definition
V1-4 (1&2=septal, 3&4=anterior)
LAD
Term
Inferior Wall MI (Leads and vessel)
Definition
II, III, aVF
RCA (posterior descending)
Term
Lateral wall MI (leads and vessel)
Definition
I, aVL, V5, V6
LAD or LCx
Term
ASE: facial flushing
Definition
Niacin
Term
ASE: Elevated LFTs, myositis
Definition
Statins
Term
ASE: GI upset, bad taste
Also binds C. diff toxin
Definition
Bile acid sequestrates (cholestyramine)
Term
Best effect on HDL
Definition
Niacin
Term
Best effect on TGs
Definition
Fibrates (genfibrozil, fenofibrate)
Term
NDHP CCBs
Definition
Verapimil
Diltiazem
Term
DHP CCBs
Definition
Amlodipine
Nifedipine
Term
What meds must be avoided in Prinzmetal's angina?
Definition
Propranolol (and other non-selective B-blockers)
ASA
Triptans
--> can cause vasospasm
Term
Mnemonic for tx CHF exacerbations
Definition
NO LIP
Nitrates
Oxygen
Loop Diuretics
Inotropes (Milrinone, dobutamine)
Position with feet hanging over side of bed
Term
Diastolic murmur heard best at left lower sternum, increases with inspiration
Definition
TS
Term
Late diastolic murmur with opening snap
Definition
MS
Term
Systolic murmur heard best in 2nd R ICS
Definition
AS
Term
Systolic murmur heard best in 2nd L ICS
Definition
PS
Term
Late systolic murmur heard best at apex
Definition
MVP
Term
Holosystolic murmur heard best at apex and radiates into axilla
Definition
MR
Term
Diastolic murmur with wide pulse pressure, head bobbing,
Definition
AR
Term
Holosystolic murmur heard best in left lower sternal border
Definition
TR, possible VSD
Term
What disease has CHF, DM & elevated LFTs?
Definition
Hemachromatosis
Term
Increased JVD with inspiration (name of sign and DDx)
Definition
Kussmal's sign
DDx: Constrictive pericarditis
Term
Jones Criteria
Definition
Joint pain
Pancarditis
Nodules
Erythema marginatum
Syndenham Chorea
Term
HACEK bacteria
Definition
Haemophilus
Actinobacillus
Cardiobacterium
Eikenella
Kingella
--> Cause culture negative endocarditis
Term
Hx of Hep B
negative p-ANCA
Renal angiography shows multiple aneurysms
Definition
Polyarteritis nodosa
Term
Coronary artery aneurysm in child
Definition
Kawasaki disease
Term
Hallmark of temporal arteritis
Definition
Increased ESR
Jaw claudication
May have Hx: polymyalgia rheumatica
Term
Young asian female with decreased upper extremity pulses
Definition
Takayasu arteritis
Term
History of asthma, nasal polyps or sinusitis
Renal problems
Postive p-ANCA
Definition
Churg-Strauss
Term
IgA depositon
Palpable purpura in children on buttocks
Definition
HSP
Term
Renal Bx shows focal necrotizing vasculitis
Granulomas in lung and upper airway
Glomerulonephritis
Positive c-ANCA
Definition
Wegeners Granulomatosis
Term
Wegeners granulomatosis serology
Definition
Postive c-ANCA
Term
MCC pneumonia in Neonate + Tx
Definition
GBS
E.coli
Listeria
Chlamydia
Tx w/ Ampicillin + Gent, Erythromycin for chlamydia
Term
MCC Pneumonia in 1m-4m + Tx
Definition
RSV
Chlamydia
Parainfluenza
Bordetella
Tx w/ Macrolide
Term
MCC pneumonia in 4m-4y + Tx
Definition
RSV
S. pneumo
H. flu
Tx w Amox or Ampicillin (IV)
Term
MCC pneumonia in 5y-15y + Tx
Definition
S. pneumo (Amox + Clarithro)
Mycoplasma (Azithro)
Chlamydia (Amox + Doxy)
Term
PNA in bird handler
Definition
Chlamydophilia psittaci
Term
PNA in bat/bird dropping exposure
Definition
Histoplasmosis
Term
PNA in pt who visited SE Cali, NM or west texas
Definition
Coccidiomycosis
Term
MCC PNA in alcoholics
Definition
Klebsiella --> "Curant jelly sputum"
Term
MCC PNA in young adults/collage students/prisoners/military
Definition
Mycoplasma
Term
Wool sorter's disease
Definition
Bacillus anthracis
Term
MCC PNA in CF pt
Definition
PSA
Term
Croup (Pathophys, S/S, Tx)
Definition
Parainfluenza
Stridor
Barky, seal-like cough
Steeple sign on CXR
Tx w/ Dexamethasone, Racemic epic if stridorous
Term
Epiglottitis (Pathophys, S/S, Tx)
Definition
H. flu type B
Stridor, Toxic appearing
Hot potato muffled voice
Tripoding
Thumb sign on CXR
DO NOT examine pharynx
Intubate
IV Abx (oxacillin, nafcillin, cefazolin, clinda or vanco) + (ceftriaxone or cefotaxime) for 7-14 d
Term
Bronchiolitis (Pathophys, S/S, Tx)
Definition
RSV
Mild URI --> cough, wheezing
Supportive care
Albuterol or Racemic epic if it helps
NO STEROIDS
Ribivirin ($$$$) - rarely used
Term
What is the orientation of the Cervical, Thoracic and Lumbar superior facets?
Definition
Cervical: BUM
Thoracic: BUL
Lumbar: BM
Term
Rule of 3s for spinous processes
Definition
T1-T3: at level
T4-6: 1/2 segment below
T7-10: 1 segment below
T-11: 1/2 segment below
T 12: at level
Term
Spine of scapula is at what vertebral level?
Definition
T3
Term
Inferior angle of scapular corresponds with which SP?
Definition
T7 SP
(NB: This equals T8 TP/vertebral body!)
Term
Sternal notch is what which vertebral level?
Definition
T2
Term
Angle of Lous is at which level?
Definition
T4
Term
Nipple is which dermatome?
Definition
T4
Term
Umbilicus is which dermatome?
Definition
T10
Term
Primary OA motion?
Definition
Flexion/Extension
Term
Primary AA motion?
Definition
Rotation
Term
Main motion of thoracic spine?
Definition
Rotation
Term
Fryettes 1st law
Definition
Neutral positon
Sidebending and rotation are OPPOSITE
Term
Fryettes 2nd law
Definition
Flexed or Extended
Sidebending and rotation are SAME side
Term
Which musle is used to treat rib 1 dysfunction?
Rib2 ?
Definition
Anterior and Middle Scalenes (1AM)
Posterior scalene (2P)
Term
What are the atypical ribs? Typicals?
Definition
Atypicals has 1 or 2 in it: 1, 2, 11, 12
Typical: 3-10
Term
Which are the true ribs? False? Floating?
Definition
Ribs 1-7 = True
Ribs 8-12= False
Ribs 11-12 = floating
Term
Ribs 1-5 have what type of motion?
Definition
Pump Handle
Term
Ribs 6-10 have what type of motion?
Definition
Bucket handle
Term
Ribs 11-12 have what type of motion?
Definition
caliper
Term
Which muscle is used to treat ribs 3-5?
Definition
Pectorals minor
Term
Which muscle is used to treat ribs 4-9
Definition
Serratus anterior
Term
Which muscle is used to treat ribs 10-11
Definition
Latissimus dorsi
Term
Which muscle is used to treat rib 12?
Definition
quadratus lumborum
Term
Respiratory function is compromised with Cobb angle of?
Definition
>50 degrees
Term
Cardiovascular function is compromised with Cobb angle of?
Definition
>75 degrees
Term
Coal Worker's Lungs / Silicosis
Definition
Progressive fibrosis
Term
Increased risk of TB w/ this occupational exposure
Definition
Silicosis
Term
Lung disease associated with space/electronics
Definition
Berylliosis
NB: increased risk of cancer with this exposure
Term
Occupational exposure assoc w/ malignant mesothelioma and bronchogenic carcinoma
Definition
abestosis
Term
Non-selective B-blockers
Definition
End of alphabet
Propranolol or Nadolol
Term
Cardioselective (B2) B-blockers
Definition
Beginning of alphabet
Atenolol, Esmolol, Metropolol
Term
Alpha and beta blockers
Definition
Carvedilol
Labetalol
Note different suffix
Term
Champan's Point for lungs
Definition
Upper lungs: 3rd ICS, sternal border

Lower Lungs: 4th ICS, sternal border
Term
Champan's Point for stomach
Definition
6th ICS, one inch lateral to sternoclavicular joint
Term
Champan's Point for pancreas
Definition
lateral to costal cartilage between 7th and 8th ribs on right
Term
Champan's Point for adrenals
Definition
2" superior, 1" lateral to umbilicus
Term
Champan's Point for kidneys
Definition
1" superior, 1" lateral to umbilicus
Term
Champan's Point for bladder
Definition
periumbilical
Term
Champan's Point for appendix
Definition
tip of 12th rib on right
Term
Champan's Point for urethra
Definition
superior margin of pubic ramus, 2 cm lateral to pubic symphysis
Term
Champan's Point for prostate
Definition
posterior margin IT band
Term
Champan's Point for colon
Definition
greater trochanter to just above knee on IT band
Term
Champan's Point for gall bladder
Definition
6th ICS, midcalvicular line
Term
Champan's Point for head structures
Definition
clavicle to 2nd rib
Term
Champan's Point for esophagus, bronchus, upper lung, lower lung
Definition
3rd - 5th ribs
Term
Champan's Point for stomach (top to bottom)
Definition
5th - 7th ribs
Term
Champan's Point for small intestines (top to bottom)
Definition
8th - 11th ribs
Term
Lab markers for Crohn's
Definition
ASCA+
Term
Lab marker for UC
Definition
+ p-ANCA
Term
Tx Crohn's
Definition
Medical management
-azathioprine/mercaptopurine
Anti-TNF alpha (infliximab)
Term
Lab marker for PBC
Definition
+ anti-mitochonrial antibodies
+ ANA
elevated Alk Phos and GGT, increased bill
Term
Tx PBC
Definition
Ursodeoxycholic acid
definitive tx: Liver transplant
Term
Lab markers for PSC
Definition
+ p-ANCA
Beads on a string on ERCP/MRCP
Assoc w/ UC (which also has + p-ANCA)
Term
Medical tx for UC
Definition
5-ASA (mesalamine) if in small bowel
Sulfasalazine (if in large bowel)
Colectomy is curative
Term
Best test for portal HTN?
Definition
SAAG >1.1
Term
Jaundice and pale stool in neonate
Definition
Biiary atresia
elevated direct bili
Term
Which antibiotic is contraindicated neonates with hyperbilirubenima?
Definition
ceftriaxone
Term
granular pattern of immune complex deposition w/ hpyercellular glomeruli
Definition
PSGN
Term
linear pattern of IgG deposition
Definition
Goodpasture's
Term
Anti-GBM antibodies, hematuria, hemoptysis
Definition
Goodpasture's
Term
Nephritis, deafness, cataracts
Definition
Alport syndrome
Term
cresecent formation in glomeruli
Definition
RPGN
Term
palpable purpura, abdominal pain, IgA nephropathy
Definition
HSP induced IgA nephropathy
Term
+ ANCA
Definition
Wegener's granulomatosis or pauci-immune RPGN
Term
Anti-dsDNA antibodies
Definition
Lupus nephritis
Term
Anti-histone antibodes
Definition
Drug induced lupus
Term
apple-green birefringence on Congo-red stain under polarized light
Definition
Amyolidosis
Term
Hyaline casts in urine
Definition
not indicative of disease
Term
RBC casts in urine
Definition
glomerulonephritis, vasculitis
Term
White cell casts in urine
Definition
Tubular interstitial disease or Acute Pyelonephritis
Term
Epithelial cell casts in urine
Definition
Acute glomerulonephritis
Term
Granular casts in urine
aka "Muddy Brown Casts"
Definition
ATN (acute tubular necrosis)
Term
Loss of epithelial foot processes
Definition
Minimal change disease
Term
Nephrotic sydrome assoc w/ Hep B
Definition
membranous glomerulonephropathy
Term
Nephrotic syndrome assoc w/ HIV
Definition
FSGS
Term
Sub-endothelial humps + tram-track appearance
Definition
MPGN
Term
segmental sclerosis and hyalinosis
Definition
FSGS
Term
spike and drome pattern of basement membrane on renal bx
Definition
membranous nephropathy
Term
Positive osmotic fragility test
Definition
Hereditary sphereocytosis
Tx w/ folic acid, RBC transfusion (PRN), and splenectomy
Term
Schistocytes on peripheral smear
Definition
hemolytic anemia or MAHA (DIC, TTP+HUS)
Term
Acanthocyte (spur call)
Definition
abetalipoproteinemia
Term
Bite cell
Definition
G6PD deficency (removes heinz body)
Term
Basophilbic stippling of RBC
Definition
sideroblastic anemia
Term
Peripherial neuropathy _ ringed sideroblasts in bone marrow
Definition
lead poisoning
Term
hypersegmented neutrophils
Definition
Megaloblastic anemia (B12 or folate deficiency)
Term
Heinz bodies
Definition
G6PD deficiency (may see bite cells also where spleen removes it)
Term
Cause of aplastic anemia and erythema infectiosum (fifth disease)
Definition
Parvovirus B19
Term
Hemolysis/Anemia
Renal Failure/Uremia
Easy bruising/bleeding (thrombocytopenia)
Neuro s/s
Fever
Definition
Thrombotic thrombocytopenia purpura (TTP)
Term
blood cell pathology associated with EBV in Africa
Definition
Burkitt lymphoma
Term
Reed sternberg-cells, cervical lymphadenopathy, night sweats
Definition
Hodgkin lymphoma
Term
Bence-Jones proteins, osteolytic lesions, high calcium
Definition
Multiple myeloma
Term
Translocation 14:18
Definition
follicular small cell lymphoma (non-hodgkin)
Term
most common lymphoma in US
Definition
diffuse large B cell lymphoma (non-hodgkin)
Term
Translocation 8:14
Definition
Burkitt lumphoma
Term
Most common type of hodgkin lymphoma
Definition
Nodular sclerosis
Term
"Starry sky pattern"
Definition
Burkitt lymphoma
Term
Elevated H&H, parities after shower, burning pains in hands and feet
Definition
polycythemia vera
Term
What infections are assoc w/ cold agglutinins?
Definition
Mycoplasma pneumonia
EBV (mono)
Term
Back pain is better with bending over/hip flexion
Definition
Spinal stenosis
--> better when leaning over shopping cart
Term
Back pain worse w/ walking/standing
Definition
Lumbar spinals stenosis
Term
Loss of ability to walk on heels/dorsiflexion?
Definition
HNP
Term
Knee X-ray shows calcification of menisci
Definition
Pseudogout
Term
Needle-shpaed, negatively birefringent crystals
Definition
Gout
Term
Rhomboid shaped, positively birefringent crystals
Definition
Pseudogout
Term
Proximal ulna fx w/ anteriorly dislocated radial head
Definition
Monteggia fx
Term
Distal radius fx w/ DRUJ dislocation
Definition
Galeazzi fx
Term
Sunburst lesion w/ periosteal elevation?
Definition
Osteosarcoma w/ codman's triangle
Term
Large destructive bone lesion with onion-skinning
Definition
Ewing sarcoma
Term
MCC Osteomyelitis overall? In Sickle cell pts? In IVDU?
Definition
MCC S. aureus
Sickle cell: Salmonella
IVDU: PSA
Term
Most common nephrotic syndrome in peds?
Definition
Minimal change disease
Term
Most common nephrotic syndrome in adults?
Definition
FSGS
Term
Kimmelstiel-Wilson lesion
Definition
Diabetic nephropathy
Term
Anti-GBM antibodies, hematuria, hempotysis
Definition
Goodpasture's
Term
Nephrotic syndrome assoc w/ Hep B
Definition
Membranoproliferative glomerulonephritis
Term
+ p-ANCA diseases
Definition
Churg-Strauss
Microscopic polyangiitis
Pauci-immune glomerulonephritis
Term
+ ACPA (ACCP) or + RF
Definition
Rheumatoid arthritis
Term
Which finger joints are affected in OA?
Definition
DIP and PIP
Term
Which finger joints are affected in RA?
Definition
PIP and MCP (but NOT DIP)
Term
Andti-Sm (Smith) Antibodies
Definition
SLE
Term
+ HLA-DR4
Definition
RA
Term
Aplastic anemia (pancytopenia) + thumb abnormalities, diffuse hypopigmentation or hyerpigmentation, Cafe-au-lait spots, short stature
Definition
Fanconi Anemia
Term
"tear drop" vesicles with prodrome of malaise, fever, pharyngitis, h/a and myalgies for 24 hrs before rash
Definition
Varicella (chicken pox)
Term
Flaccid, easy to rupture bullae, oral lesions, anti-desmosome antibodies
Definition
Pemphigus Vulgaris
Term
Antidesmosome Abs
Definition
Pemphigus vulgaris
Term
Tx Pemphigus vulgaris
Definition
Steroids, Asathioprine, treat like burn
Term
Tense, hard, difficult to rupture bullae, anti-hemidesmosome antibodies (epidermal-dermal junction)
Definition
Bullous pemphigoid
Term
Easily ruptured bullae with anti-desmosome ab's
Definition
Nikolsky's sign --> pemphigus vulgaris
Term
What should you check in pt w/ vitiligo?
Definition
TSH
Term
Anti-centromere antibody
Definition
CREST scleroderma
Term
Postive nikolsky sign
Definition
Pemphigus vulgaris
Term
Psammoma bodies in ovarian tumor
Definition
Muscinous or serous cystadenocarcinoma
Term
Choclate cyst
Definition
endometrioma
Term
What hormone do granulosa theca cell tumors produce?
Definition
Estrogen
Term
What hormone do Sertoli-Leydig cell tumors produce?
Definition
Testosterone/Androgens
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