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Disinfection, testing, chemotherapy
DTC
18
Microbiology
Graduate
05/19/2012

Additional Microbiology Flashcards

 


 

Cards

Term
Desiccation
Definition
inhibits fungal metabolism and kills most vegetative froms but not spores 
Term
Freezing 
Definition
inhibits metabolism but does not kill vegetative forms or spores 
Term
denature proteins 
Definition
heavy metals, chlorine, alcohol, phenol, formaldehyde, ethylene oxide, and peroxide 
Term
soaps and detergenst 
Definition
damage cell membranes and kill most fungal forms
Term
lyophilization with freeze-drying 
Definition
inhibits fungal metabolism and allows long term storage and cluture 
Term
Ionizing radiation 
Definition
destroys DNA and kills most fungal forms 
Term
Autoclaving 
Definition
121 C, denatures protiens and kills all fungal forms 
Term
Inceineration 
Definition
1000 C, destroys all fungal forms 
Term
Potassium hydroxide (KOH) 
Definition
quick and inexpensive causing most human tissue elments to become dissolved leaving only fungal elements
Term
Periodic Acid Shiff rxn 
Definition
stain polysaccharides on cell walls of molds and yeasts. Has aldehyde groups that bind to basic fuchsina and stain red 
Term
Giemsa Stain 
Definition
Intracellular sturcture examindation, stains blue color sometimes with a halo around them. 
Term
Nigrosin Stain 
Definition
Test demonstrating capsuls around cells 
Term
Flucytosine 
Definition
interferes with pyrimidine metabolism and inhibits both RNA and DNA synthesis 
Term
Griseofulvin 
Definition
inhibits fungal cell mitosis at metaphase by interaction with microtubules resulting in disruption of mitotic spindles
Term
Pentamidine isethionate
Definition
Interferes with nuclear metabolism by inhibition of DNA, RNA, phospholipids and protein synthesis
Term
Amphotericin B and nystatin 
Definition
bind to ergosterol and do not allow it to be incorporated into fungal cytoplasmic membranes 
Term
Fluconazole, itracanazole, ketoconazole, micronazole, thiabendazole 
Definition
inhibit ergosterol synthesis by preventing conversion of lanosterol to erosterol in the cyoplasmic membrane resulting in loss of cell membrrane integrity 
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