Term
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Definition
| results if immediate hypersensitivity reaction becomes systematic |
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Term
|
Definition
1. lower venus blood flow (obstruction, Congestive heart failure)
2. increased capillary permeability (histamine release, inflammatory response)
3. starvation (lower plasma protein concentration, lower colloid osmotic pressure) |
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Term
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Definition
-Vitamin C deficiency - required for hydroxylation of proline
- causes Brittle collagen.
- Ulceration of gums, increased hemorrhaging, slow bone
growth, slow recovery from fractures.
-decreased matrix formation
and disorganized epiphyseal plates |
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Term
| Progressive Systemic Sclerosis |
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Definition
- aberrant turnover of collagen causes Excessive collagen production
-fibers "capsule" around organs
-causes the organs to “harden” and exhibit dysfunction. |
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Term
|
Definition
-Several underlying causes, including a defect in lysyl (collagen defect)
hydroxylase (rare), procollagen peptidase, or Type III or IV collagen.
-Increased elasticity of skin, hypermobility of joints, and fragile blood
vessels |
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Term
|
Definition
-gene for fibrillin-1 mutation (elastic fibers)
-autosomal dominant
-symptoms: aortic aneurisms, pneumothorax, cataracts, dislocation of lens, skin problems |
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Term
|
Definition
| lead to congenital deafness. |
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Term
|
Definition
| lead to cataracts of the lens of the eye |
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Term
|
Definition
| demyelination of peripheral nerves |
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Term
|
Definition
occurs if antibodies are made to BP230 (also called BPAG1) or collagen type XVII (also called BPAG2), resulting in the autoimmune disease. similar to pemphigus vulgaris
-(hemidesmos |
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Term
|
Definition
-Insufficient vitamin D
-reduced absorption of calcium
and phosphorus
-cartilage matrix of epiphyseal
plate does not mineralize properly |
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Term
|
Definition
-autoimmune disease
-body produces anti-bodies to desmosomal glycoprotein (demogleins)
-causes skin blistering |
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