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Digestive
Physiology 1
67
Physiology
Undergraduate 3
08/14/2009

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Cards

Term
1. What are the 5 major processes of the digestive system?
Definition
ingestion, motility, digestion, absorption, elimination
Term
2. What is the physical break down of food done through mastication and stomach churning?
Definition
mechanical digestion
Term
3. What is the break down of large molecules into small molecules done by specific enzymes?
Definition
chemical digestion
Term
4. What are carbohydrates broken down into?
Definition
monosaccharides
Term
5. What are proteins broken down into?
Definition
peptides and amino acids
Term
6. What are fats broken down into?
Definition
fatty acids and monoglycerides
Term
7. What are some foods that are already in their simplest forms and so do not have to be digested?
Definition
vitamins, minerals, water, simple sugars (monosaccharides)
Term
8. What includes the submucosal plexus and myenteric plexus and can act autonomously to either increase or decrease motility, secretions, or sphincter tone?
Definition
enteric nervous system
Term
9. What influences the enteric nervous system?
Definition
autonomic nervous system
Term
10. What branch of the autonomic nervous system decreases motility and secretions and increases sphincter tone?
Definition
sympathetics
Term
11. What branch of the autonomic nervous system increases motility and secretions and decreases sphincter tone?
Definition
parasympathetics
Term
13. What does gastrin stimulate?
Definition
gastric acid secretion and gastric motility
Term
14. What would stimulate the release of gastrin?
Definition
amino acids, distended stomach, or parasympathetics
Term
16. Does CCK cause the gallbladder to contract?
Definition
yes
Term
17. What two hormones inhibit gastric emptying?
Definition
CCK and secretin
Term
18. What two hormones work together to stimulate secretion of HCO3- from the pancreas?
Definition
CCK and secretin
Term
19. What stimulates the release of CCK?
Definition
amino acids and lipids in duodenum, and low pH
Term
21. What are the two sister hormones that help regulate the digestive system?
Definition
CCK and secretin
Term
22. What hormone inhibits the release of gastrin?
Definition
secretin
Term
23. What stimulates the release of secretin?
Definition
lipids in duodenum and low pH
Term
24. What secretes Glucose-dependent insulinotropic peptide (GIP)?
Definition
duodenum
Term
25. What does GIP stimulate?
Definition
secretion of insulin
Term
26. What stimulates the release of GIP?
Definition
glucose in duodenum
Term
27. Where are hormones typically released?
Definition
into the blood
Term
28. Paracrines released from a cell have an effect where?
Definition
near by cells
Term
29. What are two paracrines released by the stomach?
Definition
somatostatin and histamine
Term
30. Which paracrine is released due to low gastric pH and functions to inhibit gastric acid secretion?
Definition
somatostatin
Term
31. Which paracrine is released due to parasympathetics and functions to stimulate gastric acid secretion?
Definition
histamine
Term
32. What is the semi-solid mass formed by mixing food and saliva?
Definition
bolus
Term
33. Is mastication (chewing) voluntary or involuntary?
Definition
both, voluntary can override involuntary though
Term
34. Which phase of deglutition (swallowing) is voluntary?
Definition
oral phase
Term
35. What is activated by the bolus to initiate the pharyngeal phase of deglutition?
Definition
the swallowing center in the medulla
Term
36. What occurs during the pharyngeal phase of deglutition?
Definition
soft palate pulls up, epiglottis covers glottis, upper esophageal sphincter relaxes
Term
37. Is breathing inhibited during the pharyngeal phase of deglutition?
Definition
yes - you don't want to breath in food!
Term
38. what occurs during the esophageal phase of deglutition?
Definition
upper esphageal sphincter closes, bolus through esophagus, bolus passes through cardiac sphincter
Term
39. Which layers of smooth muscle are responsible for peristalsis?
Definition
inner circular and outer longitudinal layers
Term
40. Which layers of smooth muscle are responsible for mixing?
Definition
inner circular layer
Term
41. What type of motility of the digestive tube propels contents forward?
Definition
peristalsis
Term
42. What type of contractions of the digestive tube are periodic and are responsible for propeling and mixing contents?
Definition
phasic contractions
Term
43. What type of contracitons of the digestive tube maintain a constant level of tone in the smooth muscle?
Definition
tonic contractions
Term
44. Are sphincters in the digestive tube normally relaxed or contracted, and what does stimulation of these cause?
Definition
normally contracted (closed) stimulation causes to relax (open)
Term
45. Which esophageal sphincter is skeletal muscle?
Definition
upper esophageal sphincter
Term
46. Which esophageal sphincter prevents acid reflux into esophagus?
Definition
lower esophageal sphincter (cardiac sphincter)
Term
47. What is it called when the contents of the esophagus reflux into the pharynx or oral cavity (you know - when you throw up a little in your mouth)?
Definition
laryngopharyngeal reflux (LPR)
Term
48. What is it called when the contents of the stomach reflux into the esophagus irritating the walls, causing heartburn or possibly an ulcer?
Definition
gastroesophageal reflux disease (GERD)
Term
49. What causes the pyloric sphincter to open so the stomach contents can empty into the duodenum?
Definition
peristaltic contractions in stomach
Term
50. About how much stomach contents does each peristaltic wave cause to empty out of stomach?
Definition
about 1% with each wave of contraction
Term
51. What determines how fast the stomach empties its contents?
Definition
content of stomach chyme (high in carbs - faster)(high in lipids - slower)
Term
52. What stimulates gastric emptying?
Definition
lots of stuff in stomach, increased fluidity of chyme, parasympathetics, and gastrin
Term
53. What is the most potent inhibitor of gastric emptying and why?
Definition
lipids in duodenum (CCK and secretin released) lipids slow to digest in duodenum so, they hold off emptying for a minute or two
Term
54. What other things will inhibit gastric emptying?
Definition
decreased fluidity in chyme, chyme pH < 2.0, sympathetics
Term
55. What type of movement occurs more often in the small intestine, segmentation (mixing) or peristalsis?
Definition
segmentation (mixing)
Term
56. About how long does it take for chyme to move through the small intestine?
Definition
about 3-5 hours
Term
57. What stimulates motility in the small intestine?
Definition
distention, hypertonic or hypotonic chyme, low pH in chyme, protein and enzymes that digest it
Term
58. Why do the enzymes that digest protein have to be mixed continuously in the small intestine?
Definition
if not mixed, they will start to digest the small intestine
Term
59. Do the parasympathetics play a larger role in stomach motility or small intestinal motility?
Definition
play a role in both but much larger role in stomach motility
Term
60. What happens to most of the chyme that enters the large intestine?
Definition
90% of volume is reabsorbed
Term
61. Mixing in the small intestine is called segmentation, what is mixing in the large intestine?
Definition
haustrations
Term
62. What is the point of mixing in the large intestine (it's not digestion)?
Definition
mixing to form feces
Term
63. What type of movements propel contents through the large intestine?
Definition
mass movements (moving a lot at once)
Term
64. What is the initiation of mass movement due to food in stomach called?
Definition
gastrocolic reflex
Term
65. What is the initiation of mass movement due to chyme in duodenum called?
Definition
duodenocolic reflex
Term
66. About how long does it take for contents to move through the large intestine?
Definition
about 18-24 hours
Term
67. What stimulates the defecation reflex?
Definition
distension of the rectum
Term
68. In the defecation reflex, what causes contraction of rectal walls and relaxation of internal anal sphincter?
Definition
parasympathetics
Term
69. What type of muscle is the internal anal sphincter and is it voluntary or involuntary?
Definition
smooth muscle / involuntary
Term
70. What type of muscle is the external anal sphincter and is it voluntary or involuntary?
Definition
skeletal muscle / voluntary
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