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Digestive System
Digestive physiology
66
Physiology
Undergraduate 3
04/19/2013

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Cards

Term
Mastication
Definition
Chewing
Term
What is the mechanical digestion of food?
Definition
Chewing food (mastication)
Term
What is the chemical digestion in mouth?
Definition
salivary amylase in saliva
Term
Salivary amylase (3)
Definition
begins to digest carbs as they enter mouth

In saliva

Needs a pH of 7
Term
What absorption occurs in the mouth?
Definition
None, no absorption in mouth
Term
Esophagus
Definition
Connects mouth to stomach
Term
Hypopharyngeal sphincter
Definition
Top of esophagus

Keeps air out unless you swallow
Term
Gastroesophageal sphincter
Definition
Bottom of esophagus

Keeps acid out of esophagus and in stomach

Prevents regurgitation
Term
Can you live without your stomach?
Definition
Yes, you can live without your stomach
Term
Purposes of Stomach (4)
Definition
STORAGE TANK (main purpose)

Makes gastric juice

mixes food

Intrinsic factor (serves a a carrier to ileum, allows body to absorb vit B12)
Term
What disease would you get if you didn't have a stomach?
Definition
Pernicious Anemia
-Your body couldn't absorb B 12
Term
Intrinsic Factor
Definition
Helps absorb vitamin B 12
Term
What does the stomach digest?
Definition
Protein (20%)
Term
How much protein does the stomach digest (%)
Definition
20%
Term
Purpose of stomach lining
Definition
protects stomach from gastric acid
Term
Mucus cells
Definition
Produce mucus in stomach

Alkaline to neutralize pH
Term
Purpose of mucus
Definition
Protects stomach wall from acid

Reduces friction in digestive tract
Term
What do parietal cells produce (2)
Definition
Produce HCL and Intrinsic factor
Term
What do chief cells produce
Definition
Pepsinogen
Term
Pepsinogen
Definition
Mixes with HCL to produce pepsin

Bottom layer
Term
Hydrochloric acid
Definition
Kills bacteria & organisms that could potentially be in food

Secreted in parietal cells
Term
Deglutition
Definition
Swallowing
Term
3 layers of stomach lining
Definition
Mucus

Parietal

Chief cells
Term
What drugs are absorbed in the stomach (2)
Definition
Aspirin and Alcohol
Term
Why can aspirin and alcohol produce ulcers?
Definition
Take off mucus covering in stomach
Term
Ulcers
Definition
Acid eats away stomach lining

Happens when mucus doesn't protect stomach
Term
pH of the stomach
Definition
pH 1-2
Term
Ways the stomach's emptying is influenced by the small intestine
Definition
FAT (most influential)
Acidity
Osmolarity
Distention
Hormonal
Term
Role in how fat controls stomach's emptying
Definition
An increase in fat in the small intestine decreases the amount stomach empties
Term
Role in how acidity of small intestine controls stomach's emptying
Definition
More acidic chyme that goes into small intestine, less stomach emptying
Term
Role in how osmolarity controls stomach's emptying
Definition
The more contents that are in the stomach, the greater the rate of emptying
Term
Role in how distention controls stomach's emptying
Definition
Stretching of small intestine means less emptying in the stomach

Fat increases stomach stretching
Term
Role in how hormones control stomach's emptying
Definition
Cholecystokin and secretin decrease stomach digestion
Term
G cells
Definition
secrete gastrin into the blood

Stomach endothelial cell
Term
D cells
Definition
secrete somatosatin (pancreas secretions)
Term
How much gastrin juice is produced per day?
Definition
2 to 4 liters per day
Term
Ways stomach protects itself from self-digestion (3)
Definition
Mucus production

Tight junctions

Rapid gastric epithelial cell production
Term
Layers of tissue in digestive tract wall (inner to outer)
Definition
Mucosa

Submucosa

muscularis

Serosa
Term
Pancreas (endocrine)
Definition
Islets of Langerhans
Term
Function of islets of Langerhans (2)
Definition
Produce Insulin and Glucagon

Blood sugar control
Term
Pancreas (exocrine)
Definition
Ductal cells

Acinar cells
Term
Fuction of ductal cells
Definition
Alkaline bicarbonate secretion
NaHCO3

neutralized stomach acid for the small intestine
Term
5 secretions of acinar cells
Definition
Pancreatic lipase (Fat digestion)
Pancreatic amylase (Carb digestion)

(Protein digestion)
Trypsin
Chymotrypsin
Carboxypeptidase
Term
Sphincter of Oddi
Definition
Release bile from gall bladder to small intestine
Term
Purpose of gall bladder
Definition
secretion of bile
Term
Liver
Definition
Does alot of things in digestive system
Put it down if you dont know what to do

Biochemical factory
Term
Hepatic portal system
Definition
Blood vessels throughout liver and digestive system
Term
Enterohepatic circulation
Definition
Recycling of blood and nutrients in hepatic portal system
Term
Purpose of enterohepatic circulation
Definition
(SAVES ENERGY)
Term
Functions of liver
Definition
Storage tank for zinc, iron, vitamins

Detox

Protein synthesis

Removes and secretes cholesterol and billirubin

Fat metabolisim

Bile production
Term
Billirubin
Definition
Broken down red blood cells
Term
Bile salts
Definition
emulsify (breakdown) fat in droplets
Term
Small intestine
Definition
primary site of digestion and absorption of nutrients
Term
Regions in small intestine
Definition
duodenum

Jejunum

Ileum -Most important
Term
Purpose of villi and microvilli (2)
Definition
Increase surface area- "ficks law: increases rate of absorbtion of nutrients"

Move food down tract
Term
Goblet cells
Definition
In small intestine on villi

Produce mucus, helps move food
Term
What does ileum (small intestine do)
Definition
Recycles

Allows B 12 to function (intrinsic factor)

Absorbs pancreatic enzymes
Term
Fat digestion in small intestine
Definition
100%
Term
Protein digestion in small intestine
Definition
80%
Term
Carb digestion in small intestine
Definition
whatever carbs that remain
Term
Small intestine secretion
Definition
9500mL and day
Term
How much secretion is absorbed in small intestine
Definition
all but 500mL (9000mL)
Term
Large intestine secretions
Definition
Mucus
Term
Large intestine digestion
Definition
No digestion in large intestine
Term
Absorption in large intestine (2)
Definition
Water and electrolytes
Term
How much is left for defecation?
Definition
150mL
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