Term
| Neutrophilic Leukocytosis |
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Definition
Definition: Differential Dx associated with neutrophilic leukocytosis.
1. Infection by bacteria, appendicitis, pneumonia, septicemia, etc. E.g. Staph aureus [normal flora] (induces infiltration of neutrophils to the site of infection), [strept hemolyticus, and Diplococcus pneumoniae.]--> pus forming bacteria. 90% pus due to staph
2.Metabolic or drug intoxication.
3. Necrosis of tissue as a result of MI, extensive burns, and degeneration of benign neoplasms, etc.
4. Hemorrhage (prevalent in truck driver and pregnant women), hemolysis
5. Malignancies such as leukemia of neutrophilic type |
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Term
| Eosinophilic Leukocytosis |
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Definition
1. Allergies (asthma, hay fever) to foreign PRO.
2. Chronic skin diseases such as Leprosy
3. Parasitic infestation e.g. Toxoplasmosis (cats and dogs, during pregnancy affect fetus, increase eosinophil.) and schistosomiases. |
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Term
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Definition
1. Chronic Myelocytic Leukemia (CML)
2. Viral Infection eg. Herpes zoster (nerves), Herpes simplex (comes back when immunity is low via AIDS and age) |
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Term
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Definition
1. Acute viral infection e.g. Infectious Mono, Mumps, Chicken Pox, Viral Hepatitis A is okay, C stays in the liver.
2. Chronic infection eg. Syphilis (Treponeme associated with STDs, can take care via pennicilin), (TB, Brucellosis (due to cattle and cows).) --> bacteria
3. Hematopoietic disorders eg. lymphocytic leukemia and lymphomas |
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Term
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Definition
| 1. Infection disease eg. Pulmonary TB, Rickettsial infection, Thyphoid Fever, or lymphoma. |
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Term
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Definition
Two Types of leukopenia
1. Balance Leukopenia: reduction in all types of leukocytes
2. Leukopenia in selected cell types. eg. Neutropenia (most significant), lymphopenia, eosinopenia, basopenia, monocytopenia. |
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Term
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Definition
1. Infections eg. IM, Influenza, Measles, Typhoid Fever
2. Hematopoietic disorders eg. Anemia, leukemia of lymphocytic type.
3. Chemical Agent eg. Penicillin, Streptomycin
4. Physical Agent eg. Ionizing Radiation |
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Term
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Definition
1. Diseases eg. Disseminated Lupus Erythrematosis (DLE), Systemic Lupus Erythrematosis (SLE)
SLE manifest as BUTTERFLY RASH on the face involves in production of auto-antibodies includinng:
-Auto anti-DNA abs
-Auto anti-RNA abs
-Auto anti-Proteins abs
-Auto anti-WBC abs
-Auto anti-RBC abs: Abs binds to RBC and signal for complements to lyse the RBC. --> pale looking
Control via Steroids to decrease production of auto-antibodies.
2. Stress: constant stress affect lymphocytes. IBS
3. AIDS: affect T4 lymphocytes or T helper cells leading to caposi sarcoma, pneumonia.
Usually viral infection doctor don't recommend antibiotic due to virus stimulating lymphocytosis which increase in lymphocytes to fight of the infection.
In the case of AIDS the virus induces lymphopenia which decreases the amount of lymphocytes hindering the host ability to fight off the infection. Which results in lost of weight and generalized lymphadenopathy. |
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Term
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Definition
1. Stress
2. Administration of certain hormones |
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